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8OOH
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BU of 8ooh by Molmil
Cryo-EM map of the focused refinement of the subfamily III haloalkane dehalogenase from Haloferax mediterranei dimer forming hexameric assembly.
分子名称: Alpha/beta fold hydrolase
著者Polak, M, Novacek, J, Chmelova, K, Marek, M.
登録日2023-04-05
公開日2023-10-11
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography.
Protein Sci., 32, 2023
8A1H
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BU of 8a1h by Molmil
Bacterial 6-4 photolyase from Vibrio cholerase
分子名称: 1-deoxy-1-(6,7-dimethyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-4 photolyase (FeS-BCP, ...
著者Essen, L.-O, Emmerich, H.J.
登録日2022-06-01
公開日2023-02-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and Functional Analysis of a Prokaryotic (6-4) Photolyase from the Aquatic Pathogen Vibrio Cholerae † .
Photochem.Photobiol., 99, 2023
8A67
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Branched Lys48- and Lys63-linked tri-ubiquitin (K48-K63-Ub3) in complex with matured synthetic nanobody NbSL3.3Q (3rd generation)
分子名称: CHLORIDE ION, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Lange, S.M, Kulathu, Y.
登録日2022-06-16
公開日2023-02-15
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献VCP/p97-associated proteins are binders and debranching enzymes of K48-K63-branched ubiquitin chains.
Nat.Struct.Mol.Biol., 2024
7ZPQ
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BU of 7zpq by Molmil
Structure of the RQT-bound 80S ribosome from S. cerevisiae (C1)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
登録日2022-04-28
公開日2023-02-22
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
7ZS5
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BU of 7zs5 by Molmil
Structure of 60S ribosomal subunit from S. cerevisiae with eIF6 and tRNA
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
登録日2022-05-06
公開日2023-02-22
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
7ZRS
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BU of 7zrs by Molmil
Structure of the RQT-bound 80S ribosome from S. cerevisiae (C2) - composite map
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
登録日2022-05-05
公開日2023-02-22
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
7ZUX
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Collided ribosome in a disome unit from S. cerevisiae
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
登録日2022-05-13
公開日2023-02-22
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
7ZUW
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BU of 7zuw by Molmil
Structure of RQT (C1) bound to the stalled ribosome in a disome unit from S. cerevisiae
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
登録日2022-05-13
公開日2023-02-22
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
7ZFR
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BU of 7zfr by Molmil
Crystal structure of HLA-DP (DPA1*02:01-DPB1*01:01) in complex with a peptide bound in the reverse direction
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DP alpha chain (DPA1*02:01), MHC class II HLA-DP beta chain (DPB1*01:01), ...
著者Racle, J, Guillaume, P, Larabi, A, Lau, K, Pojer, F, Gfeller, D.
登録日2022-04-01
公開日2023-04-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes.
Immunity, 56, 2023
7ZJ4
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BU of 7zj4 by Molmil
Ligand bound state of a brocolli-pepper aptamer FRET tile
分子名称: 4-(3,5-difluoro-4-hydroxybenzyl)-1,2-dimethyl-1H-imidazol-5-ol, 4-[(~{Z})-1-cyano-2-[5-[2-hydroxyethyl(methyl)amino]thieno[3,2-b]thiophen-2-yl]ethenyl]benzenecarbonitrile, POTASSIUM ION, ...
著者McRae, E.K.S, Vallina, N.S, Hansen, B.K, Boussebayle, A, Andersen, E.S.
登録日2022-04-08
公開日2023-04-19
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.43 Å)
主引用文献Structure determination of Pepper-Broccoli FRET pair by RNA origami scaffolding
To Be Published
8A58
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BU of 8a58 by Molmil
X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W
分子名称: E3 ubiquitin-protein ligase TRIM21, Ubiquitin-conjugating enzyme E2 W, ZINC ION
著者James, L.C, Kiss, L.
登録日2022-06-14
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
Nat Commun, 14, 2023
7ZIE
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BU of 7zie by Molmil
Gcf1p, multimerizes and bridges the mitochondrial DNA from Candida albicans by a specific mechanism.
分子名称: 20-mer DNA, GLYCEROL, Gcf1p
著者Tarres-Sole, A, Sola, M.
登録日2022-04-07
公開日2023-06-14
最終更新日2024-06-19
実験手法SOLUTION SCATTERING (2.9 Å), X-RAY DIFFRACTION
主引用文献Gcf1p tetramerizes upon DNA binding, revealing a novel compaction method for mitochondrial DNA in Candida albicans.
Nucleic Acids Res., 2023
8A8L
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BU of 8a8l by Molmil
Crystal structure of a staphylococcal orthologue of CYP134A1 (CYPX) in complex with a heme-coordinated fragment
分子名称: 6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole, Cytochrome P450 protein, GLYCEROL, ...
著者Snee, M, Katariya, M, Levy, C.
登録日2022-06-23
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal structure of a staphylococcal orthologue of CYP134A1 (CYPX) in complex with a heme-coordinated fragment
To Be Published
8A6W
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BU of 8a6w by Molmil
Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with cholestenone
分子名称: (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, PROTOPORPHYRIN IX CONTAINING FE, Steroid C26-monooxygenase
著者Snee, M, Amadi, C, Levy, C.
登録日2022-06-20
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with cholestenone
To Be Published
7ZJ5
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BU of 7zj5 by Molmil
Unbound state of a brocolli-pepper aptamer FRET tile.
分子名称: POTASSIUM ION, brocolli-pepper aptamer
著者McRae, E.K.S, Vallina, N.S, Hansen, B.K, Boussebayle, A, Andersen, E.S.
登録日2022-04-08
公開日2023-04-19
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献Structure determination of Pepper-Broccoli FRET pair by RNA origami scaffolding
To Be Published
7ZJV
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BU of 7zjv by Molmil
Structure of human USPL1 in covalent complex with DeltaN-SUMO2/3-PA probe
分子名称: CHLORIDE ION, SUMO-specific isopeptidase USPL1, Small ubiquitin-related modifier 2, ...
著者Zhao, Z, Gersch, M.
登録日2022-04-12
公開日2023-09-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases.
J.Am.Chem.Soc., 145, 2023
7ZJU
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BU of 7zju by Molmil
Structure of human USPL1 in covalent complex with SUMO3-2Br probe
分子名称: 2-bromanylethanamine, CALCIUM ION, CHLORIDE ION, ...
著者Zhao, Z, Gersch, M.
登録日2022-04-12
公開日2023-09-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases.
J.Am.Chem.Soc., 145, 2023
6FOY
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BU of 6foy by Molmil
The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 9
分子名称: 5-[2,3-bis(chloranyl)phenyl]furan-2-carboxylic acid, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Levy, C.W, Leys, D.
登録日2018-02-08
公開日2019-08-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites.
Commun Biol, 2, 2019
2SGP
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BU of 2sgp by Molmil
PRO 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
分子名称: OVOMUCOID INHIBITOR, PHOSPHATE ION, PROTEINASE B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2001-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
2SGQ
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BU of 2sgq by Molmil
GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
分子名称: Ovomucoid, PHOSPHATE ION, Streptogrisin B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
2SGE
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BU of 2sge by Molmil
GLU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7
分子名称: Ovomucoid, PHOSPHATE ION, POTASSIUM ION, ...
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B.
Protein Sci., 4, 1995
2SGF
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BU of 2sgf by Molmil
PHE 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B
分子名称: Ovomucoid, PHOSPHATE ION, Streptogrisin B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs
To be Published
2SGD
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BU of 2sgd by Molmil
ASP 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7
分子名称: Ovomucoid, PHOSPHATE ION, POTASSIUM ION, ...
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs
To be Published
5MLG
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BU of 5mlg by Molmil
Crystal structure of rat prorenin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin
著者Yan, Y, Read, R.
登録日2016-12-06
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of rat prorenin
To Be Published
5MKT
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BU of 5mkt by Molmil
Crystal structure of mouse prorenin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin-1
著者Yan, Y, Read, R.
登録日2016-12-05
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of mouse prorenin
To Be Published

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