1EZX

CRYSTAL STRUCTURE OF A SERPIN:PROTEASE COMPLEX

Summary for 1EZX

Entry DOI	10.2210/pdb1ezx/pdb
Descriptor	ALPHA-1-ANTITRYPSIN, TRYPSIN, ... (4 entities in total)
Functional Keywords	protease-inhibitor complex, serpin, alpha-1-antitrypsin, trypsin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Cellular location	Secreted. Short peptide from AAT: Secreted, extracellular space, extracellular matrix: P01009 P01009 Secreted, extracellular space: P00760
Total number of polymer chains	3
Total formula weight	67277.58
Authors	Huntington, J.A.,Carrell, R.W. (deposition date: 2000-05-12, release date: 2000-10-25, Last modification date: 2011-07-13)
Primary citation	Huntington, J.A.,Read, R.J.,Carrell, R.W. Structure of a serpin-protease complex shows inhibition by deformation. Nature, 407:923-926, 2000 Cited by PubMed: 11057674 DOI: 10.1038/35038119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation