3T3U
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![BU of 3t3u by Molmil](/molmil-images/mine/3t3u) | Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with Bumped Kinase Inhibitor, RM-1-130 | 分子名称: | 1,2-ETHANEDIOL, 3-(6-methoxynaphthalen-2-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1, ... | 著者 | Larson, E.T, Merritt, E.A. | 登録日 | 2011-07-25 | 公開日 | 2012-03-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1. J.Med.Chem., 55, 2012
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7RRE
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![BU of 7rre by Molmil](/molmil-images/mine/7rre) | Carbonic Anhydrase II in complex with Beta-Galactose-2C | 分子名称: | 2-[1-(1,1,3-trioxo-2,3-dihydro-1H-1lambda~6~,2-benzothiazol-6-yl)-1H-1,2,3-triazol-4-yl]ethyl beta-L-gulopyranoside, Carbonic anhydrase 2, GLYCEROL, ... | 著者 | McKenna, R, Combs, J.E. | 登録日 | 2021-08-09 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Inhibition of Carbonic Anhydrase IX and Monocarboxylate Transporters 1 and 4 in breast cancer via novel inhibition with Beta-Galactose 2C To Be Published
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7RRF
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![BU of 7rrf by Molmil](/molmil-images/mine/7rrf) | Carbonic Anhydrase IX-mimic in complex with Beta-Galactose_2C | 分子名称: | 2-[1-(1,1,3-trioxo-2,3-dihydro-1H-1lambda~6~,2-benzothiazol-6-yl)-1H-1,2,3-triazol-4-yl]ethyl beta-L-gulopyranoside, Carbonic anhydrase 2, ZINC ION | 著者 | Combs, J.E, McKenna, R. | 登録日 | 2021-08-09 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Inhibition of Carbonic Anhydrase IX and Monocarboxylate Transporters 1 and 4 in breast cancer via novel inhibition with Beta-Galactose 2C To Be Published
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8SWA
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![BU of 8swa by Molmil](/molmil-images/mine/8swa) | Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with SAM and PPNP | 分子名称: | (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Bruemmer, K.J, Pham, V.N, Toh, J.D.W. | 登録日 | 2023-05-18 | 公開日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | Formaldehyde regulates S -adenosylmethionine biosynthesis and one-carbon metabolism. Science, 382, 2023
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3I7B
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![BU of 3i7b by Molmil](/molmil-images/mine/3i7b) | Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with bumped kinase inhibitor NM-PP1 | 分子名称: | 1,2-ETHANEDIOL, 1-(1-methylethyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1, ... | 著者 | Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) | 登録日 | 2009-07-08 | 公開日 | 2010-02-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.988 Å) | 主引用文献 | Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors. Nat.Struct.Mol.Biol., 17, 2010
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6C7T
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![BU of 6c7t by Molmil](/molmil-images/mine/6c7t) | |
6CAI
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![BU of 6cai by Molmil](/molmil-images/mine/6cai) | |
3UQG
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![BU of 3uqg by Molmil](/molmil-images/mine/3uqg) | |
3UPZ
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![BU of 3upz by Molmil](/molmil-images/mine/3upz) | |
3UQF
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![BU of 3uqf by Molmil](/molmil-images/mine/3uqf) | c-SRC kinase domain in complex with BKI RM-1-89 | 分子名称: | 3-(6-ethoxynaphthalen-2-yl)-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src | 著者 | Merritt, E.A, Larson, E.T. | 登録日 | 2011-11-20 | 公開日 | 2012-03-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012
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3V51
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![BU of 3v51 by Molmil](/molmil-images/mine/3v51) | |
3V5P
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![BU of 3v5p by Molmil](/molmil-images/mine/3v5p) | |
6C8B
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![BU of 6c8b by Molmil](/molmil-images/mine/6c8b) | |
3V5T
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![BU of 3v5t by Molmil](/molmil-images/mine/3v5t) | |
6DKV
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![BU of 6dkv by Molmil](/molmil-images/mine/6dkv) | |
6C7H
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![BU of 6c7h by Molmil](/molmil-images/mine/6c7h) | |
6C7M
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![BU of 6c7m by Molmil](/molmil-images/mine/6c7m) | |
6C7V
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![BU of 6c7v by Molmil](/molmil-images/mine/6c7v) | |
3UPX
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6DC1
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![BU of 6dc1 by Molmil](/molmil-images/mine/6dc1) | Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-nitro-2-oxidanyl-benzenecarbonitrile, ... | 著者 | Jackson, C.J, Hong, N.-S, Carr, P.D. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9, 2018
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6DNJ
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![BU of 6dnj by Molmil](/molmil-images/mine/6dnj) | Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 28 round 5 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-nitro-1,2-benzoxazole, Kemp eliminase KE07 | 著者 | Jackson, C.J, Hong, N.-S, Carr, P.D. | 登録日 | 2018-06-06 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9, 2018
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6CT3
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![BU of 6ct3 by Molmil](/molmil-images/mine/6ct3) | Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 27 round 7-2 | 分子名称: | 5-nitro-2-oxidanyl-benzenecarbonitrile, GLYCEROL, Kemp eliminase, ... | 著者 | Jackson, C.J, Hong, N.-S, Carr, P.D. | 登録日 | 2018-03-22 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9, 2018
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3KFL
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![BU of 3kfl by Molmil](/molmil-images/mine/3kfl) | Leishmania major methionyl-tRNA synthetase in complex with methionyladenylate and pyrophosphate | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, MAGNESIUM ION, ... | 著者 | Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) | 登録日 | 2009-10-27 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate. Biochimie, 93, 2011
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3LC0
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4JBV
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![BU of 4jbv by Molmil](/molmil-images/mine/4jbv) | |