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6L6G
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BU of 6l6g by Molmil
Crystal structure of SeMet_Lpg0189
分子名称: GLYCEROL, Uncharacterized protein Lpg0189
著者Ge, H, Chen, X.
登録日2019-10-29
公開日2019-11-27
最終更新日2020-01-15
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structure of a hypothetical T2SS effector Lpg0189 from Legionella pneumophila reveals a novel protein fold.
Biochem.Biophys.Res.Commun., 521, 2020
6L6H
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BU of 6l6h by Molmil
Crystal structure of Lpg0189
分子名称: ACETATE ION, GLYCEROL, Uncharacterized protein Lpg0189
著者Ge, H, Chen, X.
登録日2019-10-29
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Crystal structure of a hypothetical T2SS effector Lpg0189 from Legionella pneumophila reveals a novel protein fold.
Biochem.Biophys.Res.Commun., 521, 2020
6M4J
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BU of 6m4j by Molmil
SspA in complex with cysteine
分子名称: CYSTEINE, PYRIDOXAL-5'-PHOSPHATE, SspA complex protein
著者Liu, L, Gao, H.
登録日2020-03-07
公開日2020-04-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Analysis of an l-Cysteine Desulfurase from an Ssp DNA Phosphorothioation System.
Mbio, 11, 2020
4BV6
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BU of 4bv6 by Molmil
Refined crystal structure of the human Apoptosis inducing factor
分子名称: APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Martinez-Julvez, M, Herguedas, B, Hermoso, J.A, Ferreira, P, Villanueva, R, Medina, M.
登録日2013-06-25
公開日2014-09-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Insights Into the Coenzyme Mediated Monomer-Dimer Transition of the Pro-Apoptotic Apoptosis Inducing Factor.
Biochemistry, 53, 2014
7CRF
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BU of 7crf by Molmil
Crystal structure of human TLR8 in complex with CU-CPD107
分子名称: 1-[2-(ethoxymethyl)-4-iodanyl-5-phenyl-imidazol-1-yl]-2-methyl-propan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ...
著者Sakaniwa, K, Tanji, H, Ohto, U, Shimizu, T.
登録日2020-08-13
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists.
Nat Commun, 12, 2021
7WXZ
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BU of 7wxz by Molmil
Crystal structure of the recombinant protein HR121 from the S2 protein of SARS-CoV-2
分子名称: Spike protein S2'
著者Zheng, Y.T, Ouyang, S, Pang, W, Lu, Y, Zhao, Y.B.
登録日2022-02-15
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献A variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein.
Cell Res., 32, 2022
5IGX
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BU of 5igx by Molmil
Crystal structure of NIH45-46 Fab germline precursor in complex with 426c.TM1deltaV1-3 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.TM1deltaV1-3 gp120, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scharf, L, Bjorkman, P.J.
登録日2016-02-28
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5I9Q
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BU of 5i9q by Molmil
Crystal structure of 3BNC55 Fab in complex with 426c.TM4deltaV1-3 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC55 Fab heavy chain, ...
著者Scharf, L, Chen, C, Bjorkman, P.J.
登録日2016-02-20
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
6SJ7
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BU of 6sj7 by Molmil
Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and Indisulam
分子名称: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ...
著者Srinivas, H.
登録日2019-08-12
公開日2019-12-18
最終更新日2019-12-25
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
1R7L
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BU of 1r7l by Molmil
2.0 A Crystal Structure of a Phage Protein from Bacillus cereus ATCC 14579
分子名称: Phage protein
著者Zhang, R, Joachimiak, G, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2003-10-21
公開日2004-07-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of phage protein BC1872 from Bacillus cereus, a singleton with new fold
Proteins, 64, 2006
4XAK
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BU of 4xak by Molmil
Crystal structure of potent neutralizing antibody m336 in complex with MERS Co-V RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Heavy chain of neutralizing antibody m336, ...
著者Zhou, T, Dimtrov, D.S, Ying, T.
登録日2014-12-15
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody.
Nat Commun, 6, 2015
5UR1
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BU of 5ur1 by Molmil
FGFR1 kinase domain complex with SN37333 in reversible binding mode
分子名称: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{1-[4-(dimethylamino)but-2-enoyl]piperidin-4-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one, Fibroblast growth factor receptor 1
著者Yosaatmadja, Y, Paik, W.-K, Smaill, J.B, Squire, C.J.
登録日2017-02-09
公開日2017-05-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献2-Oxo-3, 4-dihydropyrimido[4, 5-d]pyrimidinyl derivatives as new irreversible pan fibroblast growth factor receptor (FGFR) inhibitors.
Eur J Med Chem, 135, 2017
7WHK
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BU of 7whk by Molmil
The state 3 complex structure of Omicron spike with Bn03 (2-up RBD, 5 nanobodies)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2021-12-30
公開日2022-05-11
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
7WHI
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BU of 7whi by Molmil
The state 2 complex structure of Omicron spike with Bn03 (2-up RBD, 4 nanobodies)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2021-12-30
公開日2022-05-11
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
7WHJ
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BU of 7whj by Molmil
The state 1 complex structure of Omicron spike with Bn03 (1-up RBD, 3 nanobodies)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2021-12-30
公開日2022-05-11
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
7EZW
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BU of 7ezw by Molmil
Cyclic Peptide that Interacts with the eIF4E Capped-mRNA Binding Site
分子名称: ALA-CYS-GLU-MET-GLY-PHE-PHE-GLN-ASP-CYS-GLY, Eukaryotic translation initiation factor 4E, SODIUM ION
著者Brown, C.J, Ng, S, Frosi, Y.
登録日2021-06-02
公開日2022-06-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Development of a novel peptide aptamer that interacts with the eIF4E capped-mRNA binding site using peptide epitope linker evolution (PELE).
Rsc Chem Biol, 3, 2022
7F07
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BU of 7f07 by Molmil
Autonomous VH domain that interacts with eIF4E at the Capped mRNA Binding site.
分子名称: Eukaryotic translation initiation factor 4E, VH domain (VH-DiFCAP-01)
著者Brown, C.J, Frosi, Y, Ng, S, Lin, Y.C.
登録日2021-06-03
公開日2022-06-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Development of a novel peptide aptamer that interacts with the eIF4E capped-mRNA binding site using peptide epitope linker evolution (PELE).
Rsc Chem Biol, 3, 2022
3WUY
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BU of 3wuy by Molmil
Crystal structure of Nit6803
分子名称: Nitrilase
著者Yuan, Y.A, Yin, B, Wang, C.
登録日2014-05-09
公開日2014-12-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural insights into enzymatic activity and substrate specificity determination by a single amino acid in nitrilase from Syechocystis sp. PCC6803
J.Struct.Biol., 188, 2014
7X4E
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BU of 7x4e by Molmil
Structure of 10635-DndE
分子名称: DNA sulfur modification protein DndE, GLYCEROL
著者Haiyan, G, Wei, H, Chen, S, Wang, L, Wu, G.
登録日2022-03-02
公開日2022-04-20
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural and Functional Analysis of DndE Involved in DNA Phosphorothioation in the Haloalkaliphilic Archaea Natronorubrum bangense JCM10635.
Mbio, 13, 2022
5FA2
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BU of 5fa2 by Molmil
Crystal structure of 426c.TM4deltaV1-3 p120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, THIOCYANATE ION, ...
著者Scharf, L, Bjorkman, P.J.
登録日2015-12-10
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5FEC
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BU of 5fec by Molmil
Crystal structure of 3BNC60 Fab germline precursor in complex with 426c.TM4deltaV1-3 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.TM4deltaV1-3 gp120, ...
著者Scharf, L, Bjorkman, P.J.
登録日2015-12-16
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
4N0A
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BU of 4n0a by Molmil
Crystal structure of Lsm2-3-Pat1C complex from Saccharomyces cerevisiae
分子名称: DNA topoisomerase 2-associated protein PAT1, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3
著者Wu, D.H.
登録日2013-10-01
公開日2013-12-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Lsm2 and Lsm3 bridge the interaction of the Lsm1-7 complex with Pat1 for decapping activation
Cell Res., 24, 2014
7C53
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BU of 7c53 by Molmil
Crystal Structure of SARS-CoV-2 HR1 motif in complex with pan-CoVs inhibitor EK1
分子名称: CALCIUM ION, Spike protein S2',pan-CoVs inhibitor EK1
著者Zhu, Y, Yang, X, Sun, F.
登録日2020-05-19
公開日2021-05-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.278 Å)
主引用文献Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation.
Signal Transduct Target Ther, 6, 2021
7FEM
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BU of 7fem by Molmil
SARS-CoV-2 B.1.1.7 S-ACE2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Wen, Z.L, Zhu, Y, Sun, F.
登録日2021-07-21
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B.1.1.7 variant (Alpha).
Cell Discov, 7, 2021
7FET
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BU of 7fet by Molmil
SARS-CoV-2 B.1.1.7 Spike Glycoprotein trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Wen, Z.L, Zhu, Y, Sun, F.
登録日2021-07-21
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B.1.1.7 variant (Alpha).
Cell Discov, 7, 2021

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