4BV6

Refined crystal structure of the human Apoptosis inducing factor

Summary for 4BV6

Entry DOI	10.2210/pdb4bv6/pdb
Related	4BUR
Descriptor	APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... (4 entities in total)
Functional Keywords	oxidoreductase, apoptosis, nuclear chromatinolysis, dna binding
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Mitochondrion intermembrane space. Isoform 3: Mitochondrion intermembrane space. Isoform 5: Cytoplasm: O95831
Total number of polymer chains	1
Total formula weight	54821.90
Authors	Martinez-Julvez, M.,Herguedas, B.,Hermoso, J.A.,Ferreira, P.,Villanueva, R.,Medina, M. (deposition date: 2013-06-25, release date: 2014-09-17)
Primary citation	Ferreira, P.,Villanueva, R.,Martinez-Julvez, M.,Herguedas, B.,Marcuello, C.,Fernandez-Silva, P.,Cabon, L.,Hermoso, J.A.,Lostao, A.,Susin, S.A.,Medina, M. Structural Insights Into the Coenzyme Mediated Monomer-Dimer Transition of the Pro-Apoptotic Apoptosis Inducing Factor. Biochemistry, 53:4204-, 2014 Cited by PubMed: 24914854 DOI: 10.1021/BI500343R PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation