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2BB7
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BU of 2bb7 by Molmil
Mn Form Of E. coli Methionine Aminopeptidase In Complex With a quinolinyl sulfonamide inhibitor
分子名称: MANGANESE (II) ION, Methionine aminopeptidase, N-(QUINOLIN-8-YL)METHANESULFONAMIDE, ...
著者Ye, Q.Z.
登録日2005-10-17
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Metal mediated inhibition of methionine aminopeptidase by quinolinyl sulfonamides
Biochem.Biophys.Res.Commun., 339, 2006
2P98
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BU of 2p98 by Molmil
E. coli methionine aminopeptidase monometalated with inhibitor YE7
分子名称: IMIDAZO[2,1-A]ISOQUINOLINE-2-CARBOHYDRAZIDE, MANGANESE (II) ION, Methionine aminopeptidase, ...
著者Ye, Q.
登録日2007-03-24
公開日2007-11-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Inhibition of Monometalated Methionine Aminopeptidase: Inhibitor Discovery and Crystallographic Analysis.
J.Med.Chem., 50, 2007
2P9A
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BU of 2p9a by Molmil
E. coli methionine aminopeptidase dimetalated with inhibitor YE6
分子名称: 5-(2-chlorophenyl)furan-2-carbohydrazide, MANGANESE (II) ION, Methionine aminopeptidase, ...
著者Ye, Q.
登録日2007-03-24
公開日2007-11-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inhibition of Monometalated Methionine Aminopeptidase: Inhibitor Discovery and Crystallographic Analysis.
J.Med.Chem., 50, 2007
2P99
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BU of 2p99 by Molmil
E. coli methionine aminopeptidase monometalated with inhibitor YE6
分子名称: 5-(2-chlorophenyl)furan-2-carbohydrazide, MANGANESE (II) ION, Methionine aminopeptidase, ...
著者Ye, Q.
登録日2007-03-24
公開日2007-11-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Inhibition of Monometalated Methionine Aminopeptidase: Inhibitor Discovery and Crystallographic Analysis.
J.Med.Chem., 50, 2007
7CRW
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BU of 7crw by Molmil
Cryo-EM structure of rNLRP1-rDPP9 complex
分子名称: Dipeptidyl peptidase 9, NLR family protein 1
著者Huang, M.H, Zhang, X.X, Wang, J, Chai, J.J.
登録日2020-08-14
公開日2021-03-24
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structural and biochemical mechanisms of NLRP1 inhibition by DPP9.
Nature, 592, 2021
7CRV
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BU of 7crv by Molmil
Crystal structure of rNLRP1-FIIND
分子名称: NLR family protein 1
著者Huang, M.H, Zhang, X.X, Wang, J, Chai, J.J.
登録日2020-08-14
公開日2021-03-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and biochemical mechanisms of NLRP1 inhibition by DPP9.
Nature, 592, 2021
5XGH
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BU of 5xgh by Molmil
Crystal structure of PI3K complex with an inhibitor
分子名称: 3-[(4-fluorophenyl)methylamino]-5-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol, GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, ...
著者Song, K, Yang, X, Zhao, Y, Jian, Z.
登録日2017-04-13
公開日2018-04-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献New Insights into PI3K Inhibitor Design using X-ray Structures of PI3K alpha Complexed with a Potent Lead Compound.
Sci Rep, 7, 2017
3BWH
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BU of 3bwh by Molmil
Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata
分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, beta-D-xylopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L.
登録日2008-01-09
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata.
J.Struct.Biol., 164, 2008
5JFB
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BU of 5jfb by Molmil
Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163
分子名称: Scavenger receptor cysteine-rich type 1 protein M130
著者Ma, H, Jiang, L, Qiao, S, Zhang, G, Li, R.
登録日2016-04-19
公開日2017-03-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of the Fifth Scavenger Receptor Cysteine-Rich Domain of Porcine CD163 Reveals an Important Residue Involved in Porcine Reproductive and Respiratory Syndrome Virus Infection
J. Virol., 91, 2017
3U73
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BU of 3u73 by Molmil
Crystal structure of stabilized human uPAR mutant in complex with ATF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, ...
著者Huang, M.D, Xu, X, Yuan, C.
登録日2011-10-13
公開日2012-04-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal structure of the urokinase receptor in a ligand-free form.
J.Mol.Biol., 416, 2012
6XVD
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BU of 6xvd by Molmil
Crystal structure of complex of urokinase and a upain-1 variant(W3F) in pH7.4 condition
分子名称: Urokinase-type plasminogen activator, upain-1-W3F
著者Xue, G.P, Xie, X, Zhou, Y, Yuan, C, Huang, M.D, Jiang, L.G.
登録日2020-01-21
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Insight to the residue in P2 position prevents the peptide inhibitor from being hydrolyzed by serine proteases.
Biosci.Biotechnol.Biochem., 84, 2020
4N8R
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BU of 4n8r by Molmil
Crystal structure of RXRa LBD complexed with a synthetic modulator K-8008
分子名称: 5-(2-{(1Z)-2-methyl-1-[4-(propan-2-yl)benzylidene]-1H-inden-3-yl}ethyl)-1H-tetrazole, Retinoic acid receptor RXR-alpha
著者Aleshin, A.E, Su, Y, Zhang, X, Liddington, R.C.
登録日2013-10-17
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Sulindac-Derived RXR alpha Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site.
Chem.Biol., 21, 2014
4N5G
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BU of 4n5g by Molmil
Crystal Structure of RXRa LBD complexed with a synthetic modulator K8012
分子名称: 5-(2-{(1Z)-5-fluoro-2-methyl-1-[4-(propan-2-yl)benzylidene]-1H-inden-3-yl}ethyl)-1H-tetrazole, Retinoic acid receptor RXR-alpha
著者Aleshin, A.E, Su, Y, Zhang, X, Liddington, R.C.
登録日2013-10-09
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Sulindac-Derived RXR alpha Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site.
Chem.Biol., 21, 2014
7SUE
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BU of 7sue by Molmil
Crystal Structure of Human Fab S24-188 in the complex with the N-teminal Domain of Nucleocapsid protein from SARS CoV-2
分子名称: Nucleoprotein, S24-188 Fab Heavy chain, S24-188 Fab Light chain
著者Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2021-11-17
公開日2022-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
7STS
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BU of 7sts by Molmil
Crystal Structure of Human Fab S24-1379 in the Complex with the N-teminal Domain of Nucleocapsid Protein from SARS CoV-2
分子名称: Fab S24-1379, heavy chain, light chain, ...
著者Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2021-11-15
公開日2022-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
7STR
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BU of 7str by Molmil
Crystal Structure of Human Fab S24-1063 in the Complex with the N-teminal Domain of Nucleocapsid Protein from SARS CoV-2
分子名称: 1,2-ETHANEDIOL, Fab S24-1063, Heavy chain, ...
著者Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2021-11-15
公開日2022-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
7T3D
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BU of 7t3d by Molmil
CryoEM map of anchor 222-1C06 Fab and lateral patch 2B05 Fab binding H1 HA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 222-1C06 mAb heavy chain, ...
著者Han, J, Ward, A.B.
登録日2021-12-07
公開日2022-01-12
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Broadly neutralizing antibodies target a haemagglutinin anchor epitope.
Nature, 602, 2022
8HWS
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BU of 8hws by Molmil
The complex structure of Omicron BA.4 RBD with BD604, S309, and S304
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD-604 Fab Heavy chain, BD-604 Fab Light chain, ...
著者He, Q.W, Xu, Z.P, Xie, Y.F.
登録日2023-01-02
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.36 Å)
主引用文献An updated atlas of antibody evasion by SARS-CoV-2 Omicron sub-variants including BQ.1.1 and XBB.
Cell Rep Med, 4, 2023
8HWT
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BU of 8hwt by Molmil
SARS-CoV-2 Omicron BA.2 RBD complexed with BD-604 and S304 Fab
分子名称: BD-604 heavy chain, BD-604 light chain, S304 heavy chain, ...
著者He, Q.W, Xie, Y.
登録日2023-01-02
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献An updated atlas of antibody evasion by SARS-CoV-2 Omicron sub-variants including BQ.1.1 and XBB.
Cell Rep Med, 4, 2023
5MH1
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BU of 5mh1 by Molmil
Crystal structure of a DM9 domain containing protein from Crassostrea gigas
分子名称: GLYCEROL, MAGNESIUM ION, Natterin-3, ...
著者Weinert, T, Warkentin, E, Pang, G.
登録日2016-11-22
公開日2017-12-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献DM9 Domain Containing Protein Functions As a Pattern Recognition Receptor with Broad Microbial Recognition Spectrum.
Front Immunol, 8, 2017
5MH3
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Crystal structure of a DM9 domain containing protein from Crassostrea gigas with K43A mutation
分子名称: GLYCEROL, Natterin-3
著者Weinert, T, Warkentin, E, Pang, G.
登録日2016-11-22
公開日2017-12-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献DM9 Domain Containing Protein Functions As a Pattern Recognition Receptor with Broad Microbial Recognition Spectrum.
Front Immunol, 8, 2017
2EVC
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BU of 2evc by Molmil
Crystal structure of E. Coli. methionine amino peptidase in complex with 5-(2-(trifluoromethyl)phenyl)furan-2-carboxylic acid
分子名称: 5-[2-(TRIFLUOROMETHYL)PHENYL]-2-FUROIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ...
著者Huang, W.-J.
登録日2005-10-31
公開日2006-03-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural analysis of metalloform-selective inhibition of methionine aminopeptidase.
Acta Crystallogr.,Sect.D, 62, 2006
2EVM
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BU of 2evm by Molmil
crystal structure of methionine aminopeptidase in complex with 5-(2,5-dichlorophenyl)furan-2-carboxylic acid
分子名称: 5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ...
著者Huang, W.-J.
登録日2005-10-31
公開日2006-03-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural analysis of metalloform-selective inhibition of methionine aminopeptidase.
Acta Crystallogr.,Sect.D, 62, 2006
2EVO
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BU of 2evo by Molmil
crystal structure of methionine amino peptidase in complex with N-cyclopentyl-N-(thiazol-2-yl)oxalamide
分子名称: COBALT (II) ION, Methionine aminopeptidase, N1-CYCLOPENTYL-N2-(THIAZOL-2-YL)OXALAMIDE
著者Huang, W.-J.
登録日2005-10-31
公開日2006-03-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural analysis of metalloform-selective inhibition of methionine aminopeptidase.
Acta Crystallogr.,Sect.D, 62, 2006
1FO0
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BU of 1fo0 by Molmil
MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX
分子名称: NATURALLY PROCESSED OCTAPEPTIDE PBM1, PROTEIN (ALLOGENEIC H-2KB MHC CLASS I MOLECULE), PROTEIN (BETA-2 MICROGLOBULIN), ...
著者Reiser, J.B, Darnault, C, Guimezanes, A, Gregoire, C, Mosser, T, Schmitt-Verhulst, A.-M, Fontecilla-Camps, J.C, Malissen, B, Housset, D, Mazza, G.
登録日2000-08-24
公開日2000-10-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a T cell receptor bound to an allogeneic MHC molecule.
Nat.Immunol., 1, 2000

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