7YFO
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7YFR
| Structure of GluN1a E698C-GluN2D NMDA receptor in cystines non-crosslinked state. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | 著者 | Zhang, J.L, Zhu, S.J, Zhang, M. | 登録日 | 2022-07-09 | 公開日 | 2023-04-12 | 最終更新日 | 2023-08-02 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nat.Struct.Mol.Biol., 30, 2023
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6LOV
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6LOQ
| crystal structure of alpha-momorcharin in complex with cAMP | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Ribosome-inactivating protein momordin I | 著者 | Fan, X, Jin, T. | 登録日 | 2020-01-07 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.331 Å) | 主引用文献 | Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020
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6LOY
| crystal structure of alpha-momorcharin in complex with dAMP | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Ribosome-inactivating protein momordin I | 著者 | Fan, X, Jin, T. | 登録日 | 2020-01-07 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020
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6LOR
| crystal structure of alpha-momorcharin in complex with ADP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Ribosome-inactivating protein momordin I | 著者 | Fan, X, Jin, T. | 登録日 | 2020-01-07 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020
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6LOW
| crystal structure of alpha-momorcharin in complex with GMP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GUANOSINE-5'-MONOPHOSPHATE, Ribosome-inactivating protein momordin I | 著者 | Fan, X, Jin, T. | 登録日 | 2020-01-07 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020
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6LOZ
| crystal structure of alpha-momorcharin in complex with adenine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Ribosome-inactivating protein momordin I | 著者 | Fan, X, Jin, T. | 登録日 | 2020-01-07 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020
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6LP0
| crystal structure of alpha-momorcharin in complex with AMP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, Ribosome-inactivating protein momordin I | 著者 | Fan, X, Jin, T. | 登録日 | 2020-01-07 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.519 Å) | 主引用文献 | Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020
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7EU8
| Structure of the human GluN1-GluN2B NMDA receptor in complex with S-ketamine,glycine and glutamate | 分子名称: | (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Zhang, T, Zhang, Y, Zhu, S. | 登録日 | 2021-05-16 | 公開日 | 2021-07-28 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (4.07 Å) | 主引用文献 | Structural basis of ketamine action on human NMDA receptors. Nature, 596, 2021
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7EU7
| Structure of the human GluN1-GluN2A NMDA receptor in complex with S-ketamine, glycine and glutamate | 分子名称: | (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | 著者 | Zhang, Y, Zhang, T, Zhu, S. | 登録日 | 2021-05-16 | 公開日 | 2021-08-04 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of ketamine action on human NMDA receptors. Nature, 596, 2021
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7CBT
| The crystal structure of SARS-CoV-2 main protease in complex with GC376 | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase | 著者 | Shi, Y, Peng, G. | 登録日 | 2020-06-13 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.346 Å) | 主引用文献 | The preclinical inhibitor GS441524 in combination with GC376 efficaciously inhibited the proliferation of SARS-CoV-2 in the mouse respiratory tract. Emerg Microbes Infect, 10, 2021
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7W5Z
| Cryo-EM structure of Tetrahymena thermophila mitochondrial complex IV, composite dimer model | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-oxoglutarate/malate carrier protein, CARDIOLIPIN, ... | 著者 | Zhou, L, Maldonado, M, Padavannil, A, Letts, J. | 登録日 | 2021-11-30 | 公開日 | 2022-04-06 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism. Science, 376, 2022
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7XJ2
| Structure of human TRPV3_G573S in complex with Trpvicin in C4 symmetry | 分子名称: | Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide | 著者 | Fan, J, Yue, Z, Jiang, D, Lei, X. | 登録日 | 2022-04-14 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | Structural basis of TRPV3 inhibition by an antagonist. Nat.Chem.Biol., 19, 2023
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7XJ1
| Structure of human TRPV3_G573S in complex with Trpvicin in C2 symmetry | 分子名称: | Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | 著者 | Fan, J, Yue, Z, Jiang, D, Lei, X. | 登録日 | 2022-04-14 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structural basis of TRPV3 inhibition by an antagonist. Nat.Chem.Biol., 19, 2023
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7XJ3
| Structure of human TRPV3 | 分子名称: | [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, fusion of transient receptor potential cation channel subfamily V member 3 and 3C-GFP | 著者 | Fan, J, Yue, Z, Jiang, D, Lei, X. | 登録日 | 2022-04-14 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Structural basis of TRPV3 inhibition by an antagonist. Nat.Chem.Biol., 19, 2023
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7XJ0
| Structure of human TRPV3 in complex with Trpvicin | 分子名称: | Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | 著者 | Fan, J, Yue, Z, Jiang, D, Lei, X. | 登録日 | 2022-04-14 | 公開日 | 2022-11-09 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Structural basis of TRPV3 inhibition by an antagonist. Nat.Chem.Biol., 19, 2023
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7Y5N
| Structure of 1:1 PAPP-A.ProMBP complex(half map) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone marrow proteoglycan, ... | 著者 | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | 登録日 | 2022-06-17 | 公開日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2. Cell Discov, 8, 2022
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7Y5Q
| Structure of 1:1 PAPP-A.STC2 complex(half map) | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION | 著者 | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | 登録日 | 2022-06-17 | 公開日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2. Cell Discov, 8, 2022
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7EQ4
| Crystal Structure of the N-terminus of Nonstructural protein 1 from SARS-CoV-2 | 分子名称: | Host translation inhibitor nsp1 | 著者 | Liu, Y, Ke, Z, Hu, H, Zhao, K, Xiao, J, Xia, Y, Li, Y. | 登録日 | 2021-04-29 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structural Basis and Function of the N Terminus of SARS-CoV-2 Nonstructural Protein 1. Microbiol Spectr, 9, 2021
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7CCF
| Mechanism insights on steroselective oxidation of phosphorylated ethylphenols with cytochrome P450 CreJ | 分子名称: | (3-ethylphenyl) dihydrogen phosphate, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Dong, S, Du, L, Li, S.Y, Feng, Y.G. | 登録日 | 2020-06-17 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis for Selective Oxidation of Phosphorylated Ethylphenols by Cytochrome P450 Monooxygenase CreJ. Appl.Environ.Microbiol., 87, 2021
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5XJD
| TEAD in complex with fragment | 分子名称: | (2S)-2-phenyl-2-pyrrol-1-yl-ethanoic acid, Transcriptional enhancer factor TEF-3 | 著者 | Kaan, H.Y.K, Sim, A.Y.L, Tan, S.K.J, Verma, C, Song, H. | 登録日 | 2017-05-01 | 公開日 | 2018-01-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches. PLoS ONE, 12, 2017
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