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2ZFY
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BU of 2zfy by Molmil
Crystal structure of human Otubain 1
分子名称: Ubiquitin thioesterase OTUB1
著者Akutsu, M, Walker, J.R, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-01-16
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural basis and specificity of human otubain 1-mediated deubiquitination.
Biochem.J., 418, 2009
3C8X
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BU of 3c8x by Molmil
Crystal structure of the ligand binding domain of human Ephrin A2 (Epha2) receptor protein kinase
分子名称: Ephrin type-A receptor 2
著者Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-02-14
公開日2008-03-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3BRB
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BU of 3brb by Molmil
Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ...
著者Walker, J.R, Huang, X, Finerty Jr, P.J, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-12-21
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the inhibited states of the Mer receptor tyrosine kinase.
J.Struct.Biol., 165, 2009
2F4W
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BU of 2f4w by Molmil
Human ubiquitin-conjugating enzyme E2 J2
分子名称: ubiquitin-conjugating enzyme E2, J2
著者Walker, J.R, Avvakumov, G.V, Xue, S, Finerty Jr, P.J, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2005-11-24
公開日2005-12-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
3B7Y
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BU of 3b7y by Molmil
Crystal structure of the C2 Domain of the E3 Ubiquitin-Protein Ligase NEDD4
分子名称: CALCIUM ION, E3 ubiquitin-protein ligase NEDD4
著者Walker, J.R, Ruzanov, M, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-10-31
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献C2 Domain of the Human E3 Ubiquitin-Protein Ligase NEDD4.
To be Published
3B7X
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BU of 3b7x by Molmil
Crystal structure of human FK506-Binding Protein 6
分子名称: FK506-binding protein 6
著者Walker, J.R, Davis, T, Butler-Cole, C, Paramanathan, R, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-10-31
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human FK506-Binding Protein 6.
To be Published
3C5K
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BU of 3c5k by Molmil
Crystal structure of human HDAC6 zinc finger domain
分子名称: Histone deacetylase 6, ZINC ION
著者Dong, A, Ravichandran, M, Schuetz, A, Loppnau, P, Li, Y, MacKenzie, F, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Dhe-Paganon, S, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2008-01-31
公開日2008-02-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal Structure of Human HDAC6 zinc finger domain.
To be Published
2KLC
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BU of 2klc by Molmil
NMR solution structure of human ubiquitin-like domain of ubiquilin 1, Northeast Structural Genomics Consortium (NESG) target HT5A
分子名称: Ubiquilin-1
著者Doherty, R.S, Dhe-Paganon, S, Fares, C, Lemak, S, Gutmanas, A, Garcia, M, Yee, A, Montelione, G.T, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC), Ontario Centre for Structural Proteomics (OCSP)
登録日2009-06-30
公開日2009-07-14
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of ubiquitin-like domain of ubiquilin 1
To be Published
3BPR
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BU of 3bpr by Molmil
Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52
分子名称: 2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE, CHLORIDE ION, Proto-oncogene tyrosine-protein kinase MER, ...
著者Walker, J.R, Huang, X, Finerty Jr, P.J, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-12-19
公開日2008-01-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into the inhibited states of the Mer receptor tyrosine kinase.
J.Struct.Biol., 165, 2009
2KVR
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BU of 2kvr by Molmil
Solution NMR structure of human ubiquitin specific protease Usp7 UBL domain (residues 537-664). NESG target hr4395c/ SGC-Toronto
分子名称: Ubiquitin carboxyl-terminal hydrolase 7
著者Bezsonova, I, Lemak, A, Avvakumov, G, Xue, S, Dhe-Paganon, S, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)
登録日2010-03-25
公開日2010-04-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献solution structure of the ubiquitin specific protease Usp7 ubiquitin-like domain
To be Published
3CZU
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BU of 3czu by Molmil
Crystal structure of the human ephrin A2- ephrin A1 complex
分子名称: Ephrin type-A receptor 2, Ephrin-A1, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Wikstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-04-30
公開日2008-08-12
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
2NQ3
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BU of 2nq3 by Molmil
Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
分子名称: CHLORIDE ION, Itchy homolog E3 ubiquitin protein ligase
著者Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-10-30
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
To be Published
2L76
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BU of 2l76 by Molmil
Solution NMR structure of human NFATC2IP ubiquitin-like domain, NFATC2IP_244_338, NESG target HT65A/OCSP target hs00387_244_338/SGC-toronto
分子名称: NFATC2-interacting protein
著者Wu, B, Yee, A, Houliston, S, Doherty, R, Semesi, A, Dhe-Paganon, S, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP)
登録日2010-12-03
公開日2010-12-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Human NFATC2IP ubiquitin-like domains
To be Published
2HQ6
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BU of 2hq6 by Molmil
Structure of the Cyclophilin_CeCYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 from Homo Sapiens
分子名称: GLYCEROL, IODIDE ION, Serologically defined colon cancer antigen 10
著者Walker, J.R, Davis, T, Paramanathan, R, Newman, E.M, Finerty Jr, P.J, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-07-18
公開日2006-08-01
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.
PLoS Biol., 8, 2010
2L7R
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BU of 2l7r by Molmil
Solution NMR structure of N-terminal Ubiquitin-like domain of FUBI, a ribosomal protein S30 precursor from Homo sapiens. NorthEast Structural Genomics consortium (NESG) target HR6166
分子名称: Ubiquitin-like protein FUBI
著者Lemak, A, Yee, A, Houliston, S, Semesi, A, Doherty, R, Dhe-Paganon, S, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)
登録日2010-12-20
公開日2011-01-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution NMR structure of N-terminal Ubiquitin-like domain of FUBI, a ribosomal protein S30 precursor from Homo sapiens. NorthEast Structural Genomics consortium (NESG) target HR6166
To be Published
2LVA
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BU of 2lva by Molmil
NMR solution structure of the N-terminal domain of human USP28, Northeast structural genomics consortium target HT8470A
分子名称: Ubiquitin carboxyl-terminal hydrolase 28
著者Lemak, A, Yee, A, Houliston, S, Garcia, M, Dhe-Paganon, S, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)
登録日2012-06-29
公開日2012-07-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR solution structure of the N-terminal domain of human USP28
To be Published
2GFO
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BU of 2gfo by Molmil
Structure of the Catalytic Domain of Human Ubiquitin Carboxyl-terminal Hydrolase 8
分子名称: Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION
著者Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-03-22
公開日2006-04-04
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
2JXX
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BU of 2jxx by Molmil
NMR solution structure of Ubiquitin-like domain of NFATC2IP. Northeast Structural Genomics Consortium target HR5627
分子名称: NFATC2-interacting protein
著者Doherty, R.S, Dhe-Paganon, S, Fares, C, Lemak, A, Butler, C, Srisailam, S, Karra, M, Yee, A, Edwards, A.M, Weigelt, J, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)
登録日2007-11-30
公開日2007-12-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of Ubiquitin-like domain of NFATC2IP.
TO BE PUBLISHED
2FZP
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BU of 2fzp by Molmil
Crystal structure of the USP8 interaction domain of human NRDP1
分子名称: ring finger protein 41 isoform 1
著者Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-02-10
公開日2006-03-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
2L2D
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BU of 2l2d by Molmil
Solution NMR Structure of human UBA-like domain of OTUD7A_11_83, NESG target HT6304A/OCSP target OTUD7A_11_83/SGC-Toronto
分子名称: OTU domain-containing protein 7A
著者Wu, B, Yee, A, Lemak, A, Gutmanas, A, Houliston, S, Semesi, A, Dhe-Paganon, S, Montelione, G.T, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP), Structural Genomics Consortium (SGC)
登録日2010-08-17
公開日2010-09-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The amino-terminal UBA domain of OTUD7A
To be Published
2GWF
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BU of 2gwf by Molmil
Structure of a USP8-NRDP1 complex
分子名称: RING finger protein 41, Ubiquitin carboxyl-terminal hydrolase 8
著者Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-05-04
公開日2006-06-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
2LC3
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BU of 2lc3 by Molmil
Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A
分子名称: E3 ubiquitin-protein ligase HECTD1
著者Lemak, A, Yee, A, Houliston, S, Garcia, M, Arrowsmith, C, Dhe-Paganon, S, Montelione, G.T, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)
登録日2011-04-15
公開日2011-06-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR solution structure of a helical bundle from the E3 ligase HECTD1
To be Published
2KZR
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BU of 2kzr by Molmil
Solution NMR Structure of Ubiquitin thioesterase OTU1 (EC 3.1.2.-) from Mus musculus, Northeast Structural Genomics Consortium Target MmT2A
分子名称: Ubiquitin thioesterase OTU1
著者Chitayat, S, Gutmanas, A, Lemak, A, Yee, A, Bezsonova, I, Wu, B, Doherty, R.S, Semesi, A, Montelione, G.T, Arrowsmith, C.H, Dhe-Paganon, S, Northeast Structural Genomics Consortium (NESG)
登録日2010-06-23
公開日2010-07-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Northeast Structural Genomics Consortium Target MmT2A
To be Published
2I6T
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BU of 2i6t by Molmil
Orthorhombic Structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A
分子名称: GLYCEROL, SULFATE ION, UBIQUITIN-CONJUGATING ENZYME E2-LIKE ISOFORM A
著者Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Tempel, W, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S.
登録日2006-08-29
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Investigation into the L-lactate Dehydrogenase Domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A
To be Published
1ZKC
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BU of 1zkc by Molmil
Crystal Structure of the cyclophiln_RING domain of human peptidylprolyl isomerase (cyclophilin)-like 2 isoform b
分子名称: BETA-MERCAPTOETHANOL, Peptidyl-prolyl cis-trans isomerase like 2
著者Walker, J.R, Davis, T, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2005-05-02
公開日2005-08-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.
PLoS Biol., 8, 2010

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