2FZP

Crystal structure of the USP8 interaction domain of human NRDP1

Summary for 2FZP

Entry DOI	10.2210/pdb2fzp/pdb
Descriptor	ring finger protein 41 isoform 1 (2 entities in total)
Functional Keywords	e3 ligase, protein ubiquitination, structural genomics, structural genomics consortium, sgc, ligase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	16172.34
Authors	Walker, J.R.,Avvakumov, G.V.,Xue, S.,Newman, E.M.,Butler-Cole, C.,Finerty Jr., P.J.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2006-02-10, release date: 2006-03-28, Last modification date: 2024-02-14)
Primary citation	Avvakumov, G.V.,Walker, J.R.,Xue, S.,Finerty Jr., P.J.,Mackenzie, F.,Newman, E.M.,Dhe-Paganon, S. Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8). J.Biol.Chem., 281:38061-38070, 2006 Cited by PubMed: 17035239 DOI: 10.1074/jbc.M606704200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.87 Å)

Structure validation