2GWF
Structure of a USP8-NRDP1 complex
Summary for 2GWF
Entry DOI | 10.2210/pdb2gwf/pdb |
Related | 1WHB 2A9U 2FZP 2GFO |
Descriptor | Ubiquitin carboxyl-terminal hydrolase 8, RING finger protein 41 (3 entities in total) |
Functional Keywords | protein-protein complex, e3 ligase, protein ubiquitination, hydrolase, protease, ubl conjugation pathway, structural genomics, structural genomics consortium, sgc, hydrolase-ligase complex, hydrolase/ligase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P40818 |
Total number of polymer chains | 6 |
Total formula weight | 98292.61 |
Authors | Walker, J.R.,Avvakumov, G.V.,Xue, S.,Newman, E.M.,Butler-Cole, C.,Finerty Jr., P.J.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2006-05-04, release date: 2006-06-06, Last modification date: 2024-02-14) |
Primary citation | Avvakumov, G.V.,Walker, J.R.,Xue, S.,Finerty Jr., P.J.,Mackenzie, F.,Newman, E.M.,Dhe-Paganon, S. Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8). J.Biol.Chem., 281:38061-38070, 2006 Cited by PubMed: 17035239DOI: 10.1074/jbc.M606704200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report