3C8X

Crystal structure of the ligand binding domain of human Ephrin A2 (Epha2) receptor protein kinase

Summary for 3C8X

• Entry DOI: 10.2210/pdb3c8x/pdb
• Related: 1MQB
• Descriptor: Ephrin type-A receptor 2 (2 entities in total)
• Functional Keywords: atp-binding, kinase, nucleotide-binding, receptor, transferase, phosphorylation, transmembrane, tyrosine-protein kinase, glycoprotein, structural genomics consortium, sgc, phosphoprotein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane ; Single-pass type I membrane protein : P29317
• Total number of polymer chains: 1
• Total formula weight: 23568.52

Authors

Walker, J.R.,Yermekbayeva, L.,Seitova, A.,Butler-Cole, C.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2008-02-14, release date: 2008-03-25, Last modification date: 2023-08-30)

• Primary citation: Himanen, J.P.,Yermekbayeva, L.,Janes, P.W.,Walker, J.R.,Xu, K.,Atapattu, L.,Rajashankar, K.R.,Mensinga, A.,Lackmann, M.,Nikolov, D.B.,Dhe-Paganon, S.; Architecture of Eph receptor clusters.; Proc.Natl.Acad.Sci.USA, 107:10860-10865, 2010; PubMed: 20505120; DOI: 10.1073/pnas.1004148107

Experimental method

X-RAY DIFFRACTION (1.95 Å)