3C8X

Crystal structure of the ligand binding domain of human Ephrin A2 (Epha2) receptor protein kinase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Ephrin type-A receptor 2	polymer	206	23568.5	1	UniProt (P29317) Pfam (PF01404)	Homo sapiens (human)	Tyrosine-protein kinase receptor ECK, Epithelial cell kinase
2	B (A)	water	water		18.0	110	Chemie (HOH)

Sequence modifications

A: 23 - 202 (UniProt: P29317)

PDB	External Database	Details
Ala -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
Asp 6	-	expression tag
Tyr 7	-	expression tag
Asp 8	-	expression tag
Ile 9	-	expression tag
Pro 10	-	expression tag
Thr 11	-	expression tag
Thr 12	-	expression tag
Glu 13	-	expression tag
Asn 14	-	expression tag
Leu 15	-	expression tag
Tyr 16	-	expression tag
Phe 17	-	expression tag
Gln 18	-	expression tag
Gly 19	-	expression tag
Ala 20	-	expression tag
Met 21	-	expression tag
Asp 22	-	expression tag
Ile 94	Asn 94	SEE REMARK 999
Phe 95	Asn 95	SEE REMARK 999
Ile 96	Phe 96	SEE REMARK 999
Lys 99	Asn 99	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23568.5
All*	Total formula weight	23568.5

*Water molecules are not included.