8X55
| BA.2.86 Spike Trimer with T356K mutation (3 RBD down) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yue, C, Liu, P. | 登録日 | 2023-11-16 | 公開日 | 2024-06-26 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8WHW
| Spike Trimer of BA.2.86 with single RBD up | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yue, C, Liu, P. | 登録日 | 2023-09-23 | 公開日 | 2024-07-03 | 最終更新日 | 2024-08-21 | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8WHU
| Spike Trimer of BA.2.86 in complex with two hACE2s | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Processed angiotensin-converting enzyme 2, ... | 著者 | Yue, C, Liu, P. | 登録日 | 2023-09-23 | 公開日 | 2024-07-03 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8X5R
| SARS-CoV-2 BA.2.75 Spike with K356T mutation (1 RBD up) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yue, C, Liu, P. | 登録日 | 2023-11-17 | 公開日 | 2024-07-03 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8WHV
| Spike Trimer of BA.2.86 with three RBDs down | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yue, C, Liu, P. | 登録日 | 2023-09-23 | 公開日 | 2024-07-03 | 最終更新日 | 2024-08-21 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8XUR
| BA.2.86 Spike Trimer in complex with heparan sulfate | 分子名称: | 2-O-sulfo-beta-L-altropyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yue, C, Liu, P. | 登録日 | 2024-01-14 | 公開日 | 2024-07-03 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8XUU
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8X50
| BA.2.86 Spike Trimer with ins483V mutation (1 RBD up) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yue, C, Liu, P. | 登録日 | 2023-11-16 | 公開日 | 2024-06-26 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8XUT
| XBB.1.5 Spike Trimer in complex with heparan sulfate | 分子名称: | 2-O-sulfo-beta-L-altropyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yue, C, Liu, P, Mao, X. | 登録日 | 2024-01-14 | 公開日 | 2024-07-03 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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4X9Z
| Dimeric conotoxin alphaD-GeXXA | 分子名称: | alphaD-conotoxin GeXXA from the venom of Conus generalis | 著者 | Xu, S, Zhang, T, Kompella, S, Adams, D, Ding, J, Wang, C. | 登録日 | 2014-12-12 | 公開日 | 2015-12-02 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Conotoxin alpha D-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors Sci Rep, 5, 2015
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4M5C
| Crystal Structure of an Truncated Transition metal Transporter | 分子名称: | COBALT (II) ION, Cobalamin biosynthesis protein CbiM, HEXANE-1,6-DIOL | 著者 | Yu, Y, Zhou, M.Z, Gu, J.K. | 登録日 | 2013-08-08 | 公開日 | 2014-03-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Planar substrate-binding site dictates the specificity of ECF-type nickel/cobalt transporters Cell Res., 24, 2014
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5IH8
| MELK in complex with NVS-MELK1 | 分子名称: | Maternal embryonic leucine zipper kinase, N-[(pyridin-2-yl)methyl]-4-[4-(pyridin-4-yl)-1H-pyrazol-1-yl]benzamide | 著者 | Sprague, E.R, Puleo, D.E. | 登録日 | 2016-02-29 | 公開日 | 2016-06-01 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight. J.Med.Chem., 59, 2016
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5IH9
| MELK in complex with NVS-MELK8A | 分子名称: | 1-methyl-4-[4-(4-{3-[(piperidin-4-yl)methoxy]pyridin-4-yl}-1H-pyrazol-1-yl)phenyl]piperazine, Maternal embryonic leucine zipper kinase | 著者 | Sprague, E.R, Puleo, D.E. | 登録日 | 2016-02-29 | 公開日 | 2016-06-01 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight. J.Med.Chem., 59, 2016
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6RU3
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6RU5
| human complement C3 in complex with the hC3Nb1 nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Jensen, R.K, Andersen, G.R. | 登録日 | 2019-05-27 | 公開日 | 2019-08-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6RUR
| Structure of the SCIN stabilized C3bBb convertase bound to properdin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, ... | 著者 | Pedersen, D.V, Gadeberg, T.A.F, Andersen, G.R. | 登録日 | 2019-05-29 | 公開日 | 2019-08-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (6 Å) | 主引用文献 | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6RUS
| Structure of a functional properdin monomer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, SULFATE ION, ... | 著者 | Pedersen, D.V, Andersen, G.R. | 登録日 | 2019-05-29 | 公開日 | 2019-08-21 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6RUV
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6LB9
| Magnesium ion-bound SspB crystal structure | 分子名称: | DUF4007 domain-containing protein, MAGNESIUM ION | 著者 | Liqiong, L, Yubing, Z. | 登録日 | 2019-11-13 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.227 Å) | 主引用文献 | SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities. Nat Microbiol, 5, 2020
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6SKB
| Crystal Structure of Human Kallikrein 6 (N217D/I218Y/K224R) in complex with GSK3496783A | 分子名称: | 4-[(3~{R})-1-oxidanyl-3,4-dihydro-2,1-benzoxaborinin-3-yl]-2-(pyridin-3-ylmethoxy)benzenecarboximidamide, 4-[(3~{S})-1-oxidanyl-3,4-dihydro-2,1-benzoxaborinin-3-yl]-2-(pyridin-3-ylmethoxy)benzenecarboximidamide, GLYCEROL, ... | 著者 | Thorpe, J.H. | 登録日 | 2019-08-15 | 公開日 | 2019-09-25 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors. Bioorg.Med.Chem.Lett., 29, 2019
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6SEJ
| Structure of a functional monomeric properdin lacking TSR3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, alpha-D-mannopyranose, ... | 著者 | Pedersen, D.V, Andersen, G.R. | 登録日 | 2019-07-30 | 公開日 | 2019-08-21 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.501 Å) | 主引用文献 | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6LNA
| YdiU complex with AMPNPP and Mn2+ | 分子名称: | CALCIUM ION, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Li, B, Yang, Y, Ma, Y. | 登録日 | 2019-12-28 | 公開日 | 2020-12-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | The YdiU Domain Modulates Bacterial Stress Signaling through Mn 2+ -Dependent UMPylation. Cell Rep, 32, 2020
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4M58
| Crystal Structure of an transition metal transporter | 分子名称: | Cobalamin biosynthesis protein CbiM, NICKEL (II) ION | 著者 | Yu, Y, Yan, C.Y, Zhang, B, Li, X.L, Gu, J.K. | 登録日 | 2013-08-08 | 公開日 | 2014-03-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Planar substrate-binding site dictates the specificity of ECF-type nickel/cobalt transporters Cell Res., 24, 2014
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6M3B
| hAPC-c25k23 Fab complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Vitamin K-dependent protein C heavy chain, Vitamin K-dependent protein C light chain, ... | 著者 | Wang, X, Li, L, Zhao, X, Egner, U. | 登録日 | 2020-03-03 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia. Nat Commun, 11, 2020
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7MLM
| Crystal structure of mouse TLR4/MD-2 in complex with sulfatides | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Su, L, Beutler, B. | 登録日 | 2021-04-28 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | Sulfatides are endogenous ligands for the TLR4-MD-2 complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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