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7LVA
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BU of 7lva by Molmil
Solution structure of the HIV-1 PBS-segment
分子名称: RNA (103-MER)
著者Heng, X, Song, Z.
登録日2021-02-24
公開日2021-03-17
最終更新日2024-05-15
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献The three-way junction structure of the HIV-1 PBS-segment binds host enzyme important for viral infectivity.
Nucleic Acids Res., 49, 2021
1GIS
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BU of 1gis by Molmil
A TRICHOSANTHIN(TCS) MUTANT(E85Q) COMPLEX STRUCTURE WITH 2'-DEOXY-ADENOSIN-5'-MONOPHOSPHATE
分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN
著者Guo, Q, Liu, Y, Dong, Y, Rao, Z.
登録日2001-03-15
公開日2003-06-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants.
Protein Eng., 16, 2003
1GYA
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BU of 1gya by Molmil
N-GLYCAN AND POLYPEPTIDE NMR SOLUTION STRUCTURES OF THE ADHESION DOMAIN OF HUMAN CD2
分子名称: HUMAN CD2, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Wyss, D.F, Choi, J.S, Wagner, G.
登録日1995-05-26
公開日1996-11-08
最終更新日2020-07-29
実験手法SOLUTION NMR
主引用文献Conformation and function of the N-linked glycan in the adhesion domain of human CD2.
Science, 269, 1995
4F1P
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BU of 4f1p by Molmil
Crystal Structure of mutant S554D for ArfGAP and ANK repeat domain of ACAP1
分子名称: Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1, SULFATE ION, ...
著者Sun, F, Pang, X, Zhang, K, Ma, J, Zhou, Q.
登録日2012-05-07
公開日2012-07-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanistic insights into regulated cargo binding by ACAP1 protein
J.Biol.Chem., 287, 2012
7JOV
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BU of 7jov by Molmil
CRYSTAL STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE 2 (ROCK2) IN COMPLEX WITH A PHENYLPYRAZOLE AMIDE INHIBITOR
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, N-[(1S)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1H-pyrazol-4-yl)benzamide, ...
著者Muckelbauer, J.K.
登録日2020-08-07
公開日2020-09-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.586 Å)
主引用文献Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies.
Bioorg.Med.Chem.Lett., 30, 2020
7YDQ
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BU of 7ydq by Molmil
Structure of PfNT1(Y190A)-GFP in complex with GSK4
分子名称: 5-methyl-N-[2-(2-oxidanylideneazepan-1-yl)ethyl]-2-phenyl-1,3-oxazole-4-carboxamide, Nucleoside transporter 1,Green fluorescent protein
著者Wang, C, Yu, L.Y, Li, J.L, Ren, R.B, Deng, D.
登録日2022-07-04
公開日2023-04-26
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.04 Å)
主引用文献Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
6VUA
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BU of 6vua by Molmil
X-ray structure of human CD38 catalytic domain with 2'-Cl-araNAD+
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, DI(HYDROXYETHYL)ETHER, ...
著者Dai, Z, Zhang, X.N, Nasertorabi, F, Han, G.W, Stevens, R.C, Zhang, Y.
登録日2020-02-14
公開日2020-06-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Synthesis of site-specific antibody-drug conjugates by ADP-ribosyl cyclases.
Sci Adv, 6, 2020
4FZ3
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BU of 4fz3 by Molmil
Crystal structure of SIRT3 in complex with acetyl p53 peptide coupled with 4-amino-7-methylcoumarin
分子名称: NAD-dependent protein deacetylase sirtuin-3, mitochondrial, ZINC ION, ...
著者Liu, D, Wu, J, Zhang, D, Chen, K, Jiang, H, Liu, H.
登録日2012-07-06
公開日2013-03-20
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery and Mechanism Study of SIRT1 Activators that Promote the Deacetylation of Fluorophore-Labeled Substrate
J.Med.Chem., 56, 2013
3HJ2
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BU of 3hj2 by Molmil
Crystal structure of covalent dimer of HNP1
分子名称: HUMAN NEUTROPHIL PEPTIDE 1
著者Lubkowski, J, Pazgier, M, Lu, W.
登録日2009-05-20
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献What Dictates the Multifaced Functions of the Human alpha-Defensin HNP1?
To be Published
3HJD
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BU of 3hjd by Molmil
X-ray structure of monomeric variant of HNP1
分子名称: Human neutrophil peptide 1
著者Lubkowski, J, Pazgier, M, Lu, W.
登録日2009-05-21
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献What Dictates the Multifaced Functions of the Human alpha-Defensin HNP?
To be Published
8IND
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BU of 8ind by Molmil
Crystal structure of UGT74AN3-UDP-RES
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-[(1R,2S,4R,6R,7R,10S,11S,14S,16R)-14-hydroxy-7,11-dimethyl-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-6-yl]pyran-2-one, Glycosyltransferase, ...
著者Huang, W.
登録日2023-03-09
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3
Acs Catalysis, 14, 2024
8INV
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BU of 8inv by Molmil
Crystal structure of UGT74AN3-UDP-BUF
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, ...
著者Long, F, Huang, W.
登録日2023-03-10
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3
Acs Catalysis, 14, 2024
8INA
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BU of 8ina by Molmil
Crystal structure of UGT74AN3-UDP
分子名称: GLYCEROL, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE
著者Long, F, Huang, W.
登録日2023-03-09
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3
Acs Catalysis, 14, 2024
8X17
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BU of 8x17 by Molmil
Cryo-EM structure of adenosine receptor A3AR bound to CF102
分子名称: Adenosine receptor A3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Cai, H, Xu, Y, Xu, H.E.
登録日2023-11-06
公開日2024-04-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Cryo-EM structures of adenosine receptor A 3 AR bound to selective agonists.
Nat Commun, 15, 2024
8XAX
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BU of 8xax by Molmil
Cryo-EM structure of an anti-phage defense complex bound to AMPPNP and DNA at state 2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding protein, DUF4297, ...
著者An, Q, Deng, Z.
登録日2023-12-05
公開日2024-06-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex.
Cell Res., 2024
8INO
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BU of 8ino by Molmil
Crystal structure of UGT74AN3 in complex UDP and PER
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(3S,5S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3,5,14-tris(oxidanyl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, Glycosyltransferase, ...
著者Long, F, Huang, W.
登録日2023-03-10
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3
Acs Catalysis, 14, 2024
8WZB
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BU of 8wzb by Molmil
RS head-neck monomer
分子名称: DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ...
著者Meng, X, Cong, Y.
登録日2023-11-01
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia.
Nat Commun, 15, 2024
8X2U
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BU of 8x2u by Molmil
Radial spoke head-neck dimer
分子名称: DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ...
著者Meng, X, Cong, Y.
登録日2023-11-10
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia.
Nat Commun, 15, 2024
8XAU
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BU of 8xau by Molmil
Cryo-EM structure of HerA
分子名称: ATP-binding protein
著者Wang, Y, Deng, Z.
登録日2023-12-05
公開日2024-06-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex.
Cell Res., 2024
8XAV
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BU of 8xav by Molmil
Cryo-EM structure of an anti-phage defense complex
分子名称: ATP-binding protein, DUF4297
著者Wang, Y, Deng, Z.
登録日2023-12-05
公開日2024-06-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex.
Cell Res., 2024
8FDY
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BU of 8fdy by Molmil
Human GAR transformylase in complex with GAR substrate and AGF132 inhibitor
分子名称: GLYCINAMIDE RIBONUCLEOTIDE, N-{5-[4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl]pyridine-2-carbonyl}-L-glutamic acid, Phosphoribosylglycinamide formyltransferase
著者Wong-Roushar, J, Dann III, C.E.
登録日2022-12-05
公開日2023-05-10
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Multitargeted 6-Substituted Thieno[2,3- d ]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism.
Acs Pharmacol Transl Sci, 6, 2023
8XAW
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BU of 8xaw by Molmil
Cryo-EM structure of an anti-phage defense complex bound to AMPPNP and DNA at state 1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding protein, DUF4297, ...
著者An, Q, Deng, Z.
登録日2023-12-05
公開日2024-06-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex.
Cell Res., 2024
8X16
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BU of 8x16 by Molmil
Cryo-EM structure of adenosine receptor A3AR bound to CF101
分子名称: Adenosine receptor A3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Cai, H, Xu, Y, Xu, H.E.
登録日2023-11-06
公開日2024-04-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Cryo-EM structures of adenosine receptor A 3 AR bound to selective agonists.
Nat Commun, 15, 2024
8WYP
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BU of 8wyp by Molmil
High Resolution Crystal Structure of Brd4 BD-1 in Complex with a Novel Inhibitor Precursor
分子名称: 3-bromanylimidazo[1,2-a]pyridin-6-amine, Bromodomain-containing protein 4
著者Liu, B, Ma, X.
登録日2023-10-31
公開日2024-05-22
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献High resolution crystal structure of BRD4-BD1 in complex with a novel inhibitor precursor.
Biochem.Biophys.Res.Commun., 690, 2024
8XAY
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BU of 8xay by Molmil
Cryo-EM structure of an anti-phage defense complex bound to ATPrS and DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding protein, DUF4297, ...
著者An, Q, Deng, Z.
登録日2023-12-05
公開日2024-06-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex.
Cell Res., 2024

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