8X16

Cryo-EM structure of adenosine receptor A3AR bound to CF101

Summary for 8X16

• Entry DOI: 10.2210/pdb8x16/pdb
• EMDB information: 37985
• Descriptor: Adenosine receptor A3, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
• Functional Keywords: gpcr, adenosine a3 receptor, ligand selectivity, cf101, membrane protein, membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 149223.75

Authors

Cai, H.,Xu, Y.,Xu, H.E. (deposition date: 2023-11-06, release date: 2024-04-24, Last modification date: 2024-05-08)

• Primary citation: Cai, H.,Guo, S.,Xu, Y.,Sun, J.,Li, J.,Xia, Z.,Jiang, Y.,Xie, X.,Xu, H.E.; Cryo-EM structures of adenosine receptor A 3 AR bound to selective agonists.; Nat Commun, 15:3252-3252, 2024; PubMed: 38627384; DOI: 10.1038/s41467-024-47207-6

Experimental method

ELECTRON MICROSCOPY (3.29 Å)