5C4L
 
 | | Conformational alternate of sisomicin in complex with APH(2")-IVa | | 分子名称: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, (2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-ol, APH(2'')-Id | | 著者 | Kaplan, E, Guichou, J.F, Berrou, K, Chaloin, L, Leban, N, Lallemand, P, Barman, T, Serpersu, E.H, Lionne, C. | | 登録日 | 2015-06-18 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Aminoglycoside binding and catalysis specificity of aminoglycoside 2-phosphotransferase IVa: A thermodynamic, structural and kinetic study.
Biochim.Biophys.Acta, 1860, 2016
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3S9S
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3NOL
 | | Crystal structure of Zymomonas mobilis Glutaminyl Cyclase (trigonal form) | | 分子名称: | CALCIUM ION, GLYCEROL, Glutamine cyclotransferase, ... | | 著者 | Parthier, C, Carrillo, D.R, Stubbs, M.T. | | 登録日 | 2010-06-25 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus
Biol.Chem., 391, 2010
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3NOK
 | | Crystal structure of Myxococcus xanthus Glutaminyl Cyclase | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, ... | | 著者 | Parthier, C, Carrillo, D.R, Stubbs, M.T. | | 登録日 | 2010-06-25 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus
Biol.Chem., 391, 2010
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3NOM
 | | Crystal Structure of Zymomonas mobilis Glutaminyl Cyclase (monoclinic form) | | 分子名称: | CALCIUM ION, GLYCEROL, Glutamine cyclotransferase, ... | | 著者 | Parthier, C, Carrillo, D.R, Stubbs, M.T. | | 登録日 | 2010-06-25 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus
Biol.Chem., 391, 2010
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1AYN
 | | HUMAN RHINOVIRUS 16 COAT PROTEIN | | 分子名称: | HUMAN RHINOVIRUS 16 COAT PROTEIN, LAURIC ACID, MYRISTIC ACID, ... | | 著者 | Hadfield, A.T, Oliveira, M.A, Zhao, R, Rossmann, M.G. | | 登録日 | 1997-11-06 | | 公開日 | 1998-01-21 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The structure of human rhinovirus 16.
Structure, 1, 1993
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6I9B
 | | NMR structure of the La module from human LARP4A | | 分子名称: | La-related protein 4 | | 著者 | Conte, M.R, Martino, L, Atkinson, R.A, Kelly, G, Cruz-Gallardo, I, De Tito, S, Trotta, R. | | 登録日 | 2018-11-22 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.
Nucleic Acids Res., 47, 2019
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5B0V
 | | Crystal Structure of Marburg virus VP40 Dimer | | 分子名称: | ETHANOL, Matrix protein VP40 | | 著者 | Oda, S, Bornholdt, Z.A, Abelson, D.M, Saphire, E.O. | | 登録日 | 2015-11-05 | | 公開日 | 2016-01-20 | | 最終更新日 | 2016-03-09 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression
J.Virol., 90, 2015
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2G8X
 | | Escherichia coli Y209W apoprotein | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CARBONATE ION, PHOSPHATE ION, ... | | 著者 | Lee, T.T, Finer-Moore, J.S, Stroud, R.M. | | 登録日 | 2006-03-03 | | 公開日 | 2006-03-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | The role of protein dynamics in thymidylate synthase catalysis: Variants of conserved dUMP-binding Tyr-261
TO BE PUBLISHED
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1C8M
 | | REFINED CRYSTAL STRUCTURE OF HUMAN RHINOVIRUS 16 COMPLEXED WITH VP63843 (PLECONARIL), AN ANTI-PICORNAVIRAL DRUG CURRENTLY IN CLINICAL TRIALS | | 分子名称: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, HUMAN RHINOVIRUS 16 COAT PROTEIN, ZINC ION | | 著者 | Chakravarty, S, Bator, C.M, Pevear, D.C, Diana, G.D, Rossmann, M.G. | | 登録日 | 2000-05-26 | | 公開日 | 2000-11-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | THE REFINED STRUCTURE OF A PICORNAVIRUS INHIBITOR CURRENTLY IN CLINICAL TRIALS, WHEN COMPLEXED WITH HUMAN RHINOVIRUS 16
to be published
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5CKA
 | | Human beta-2 microglobulin double mutant W60G-N83V | | 分子名称: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | | 登録日 | 2015-07-15 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
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5CKG
 | | Human beta-2 microglobulin mutant V85E | | 分子名称: | ACETATE ION, Beta-2-microglobulin, GLYCEROL | | 著者 | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | | 登録日 | 2015-07-15 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
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7PUX
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5CFH
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3ISW
 | | Crystal structure of filamin-A immunoglobulin-like repeat 21 bound to an N-terminal peptide of CFTR | | 分子名称: | Cystic fibrosis transmembrane conductance regulator, Filamin-A | | 著者 | Xu, Z, Page, R, Qin, J, Ithychanda, S.S, Liu, J.M, Misra, S. | | 登録日 | 2009-08-27 | | 公開日 | 2010-04-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Biochemical basis of the interaction between cystic fibrosis transmembrane conductance regulator and immunoglobulin-like repeats of filamin.
J.Biol.Chem., 285, 2010
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6FIB
 | | Structure of human 4-1BB ligand | | 分子名称: | Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor ligand superfamily member 9,4-1BBL -CH/CL fusion, Tumor necrosis factor ligand superfamily member 9,Uncharacterized protein | | 著者 | Joseph, C, Claus, C, Ferrara, C, von Hirschheydt, T, Prince, C, Funk, D, Klein, C, Benz, J. | | 登録日 | 2018-01-17 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.
Sci Transl Med, 11, 2019
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7QGQ
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3IHG
 | | Crystal structure of a ternary complex of aklavinone-11 hydroxylase with FAD and aklavinone | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, RdmE, SULFATE ION, ... | | 著者 | Lindqvist, Y, Koskiniemi, H, Jansson, A, Sandalova, T, Schneider, G. | | 登録日 | 2009-07-30 | | 公開日 | 2009-09-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Structural basis for substrate recognition and specificity in aklavinone-11-hydroxylase from rhodomycin biosynthesis.
J.Mol.Biol., 393, 2009
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8ETN
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5CSG
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8FQ4
 | | AAV1 VP3 Only Capsid | | 分子名称: | Capsid protein | | 著者 | Mietzsch, M, McKenna, R. | | 登録日 | 2023-01-05 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | | 主引用文献 | Production and characterization of an AAV1-VP3-only capsid: An analytical benchmark standard.
Mol Ther Methods Clin Dev, 29, 2023
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5CSB
 | | The crystal structure of beta2-microglobulin D76N mutant at room temperature | | 分子名称: | Beta-2-microglobulin | | 著者 | de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S. | | 登録日 | 2015-07-23 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.719 Å) | | 主引用文献 | Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
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5CS7
 | | The crystal structure of wt beta2-microglobulin at room temperature | | 分子名称: | Beta-2-microglobulin | | 著者 | de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S. | | 登録日 | 2015-07-23 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
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2G8A
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8D9N
 | | CryoEM structures of bAE1 captured in multiple states. | | 分子名称: | Anion exchange protein | | 著者 | Zhekova, H.R, Wang, W.G, Jiang, J.S, Tsirulnikov, K, Muhammad-Khan, G.H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Tieleman, P, Zhou, Z.H, Pushkin, A, Kurtz, I. | | 登録日 | 2022-06-10 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations.
Commun Biol, 5, 2022
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