4OEO
 
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6ENY
 | | Structure of the human PLC editing module | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ... | | 著者 | Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R. | | 登録日 | 2017-10-07 | | 公開日 | 2017-11-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | Structure of the human MHC-I peptide-loading complex.
Nature, 551, 2017
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7ZBU
 | | CryoEM structure of SARS-CoV-2 spike monomer in complex with neutralising antibody P008_60 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-2-[[5-[(3-ethyl-4-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, P008_60 antibody, ... | | 著者 | Rosa, A, Pye, V.E, Cronin, N, Cherepanov, P. | | 登録日 | 2022-03-24 | | 公開日 | 2022-08-17 | | 最終更新日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (4.31 Å) | | 主引用文献 | A neutralizing epitope on the SD1 domain of SARS-CoV-2 spike targeted following infection and vaccination.
Cell Rep, 40, 2022
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6I2D
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2RHL
 | | Synthetic Gene Encoded Bacillus Subtilis FtsZ NCS Dimer with Bound GDP | | 分子名称: | Cell Division Protein ftsZ, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Lovell, S, Halloran, Z, Hjerrild, K, Sheridan, D, Burgin, A, Stewart, L, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | | 登録日 | 2007-10-09 | | 公開日 | 2008-10-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer.
BMC Biotechnol., 9, 2009
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4Y37
 | | Endothiapepsin in complex with fragement 305 | | 分子名称: | 4-chloro-2-methylthieno[2,3-d][1,2,3]diazaborinin-1(2H)-ol, ACETATE ION, Endothiapepsin, ... | | 著者 | Krimmer, S.G, Heine, A, Klebe, G. | | 登録日 | 2015-02-10 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Crystallographic Fragment Screening of an Entire Library
To Be Published
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6EQT
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6P2K
 | | Crystal structure of AFV00434, an ancestral GH74 enzyme | | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Stogios, P.J, Skarina, T, Arnal, G, Brumer, H, Savchenko, A. | | 登録日 | 2019-05-21 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74.
J.Biol.Chem., 294, 2019
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1F06
 | | THREE DIMENSIONAL STRUCTURE OF THE TERNARY COMPLEX OF CORYNEBACTERIUM GLUTAMICUM DIAMINOPIMELATE DEHYDROGENASE NADPH-L-2-AMINO-6-METHYLENE-PIMELATE | | 分子名称: | L-2-AMINO-6-METHYLENE-PIMELIC ACID, MESO-DIAMINOPIMELATE D-DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Cirilli, M, Scapin, G, Sutherland, A, Caplan, J.F, Vederas, J.C, Blanchard, J.S. | | 登録日 | 2000-05-14 | | 公開日 | 2001-05-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The three-dimensional structure of the ternary complex of Corynebacterium glutamicum diaminopimelate dehydrogenase-NADPH-L-2-amino-6-methylene-pimelate.
Protein Sci., 9, 2000
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5I17
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV3-20 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, SULFATE ION | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2016-08-03 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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6P6U
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1F39
 | | CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR C-TERMINAL DOMAIN | | 分子名称: | REPRESSOR PROTEIN CI | | 著者 | Bell, C.E, Frescura, P, Hochschild, A, Lewis, M. | | 登録日 | 2000-06-01 | | 公開日 | 2000-07-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the lambda repressor C-terminal domain provides a model for cooperative operator binding.
Cell(Cambridge,Mass.), 101, 2000
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2RD3
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6P57
 | | Crystal Structure of the Beta Subunit of Luteinizing Hormone | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Lutropin subunit beta, alpha-D-mannopyranose, ... | | 著者 | McPherson, A. | | 登録日 | 2019-05-29 | | 公開日 | 2019-12-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | | 主引用文献 | The Crystal Structure of the Beta Subunit of Luteinizing Hormone and a Model for the Intact Hormone
Curr Res Struct Biol, 2019
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6I8Y
 | | Crystal structure of Spindlin1 in complex with the Methyltransferase inhibitor A366 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 5'-methoxy-6'-[3-(pyrrolidin-1-yl)propoxy]spiro[cyclobutane-1,3'-indol]-2'-amine, ... | | 著者 | Srikannathasan, V, Johansson, C, Gileadi, C, Shrestha, L, Sorrell, F.J, Krojer, T, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. | | 登録日 | 2018-11-21 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.
J.Med.Chem., 62, 2019
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4PPZ
 | | Crystal structure of zinc-bound succinyl-diaminopimelate desuccinylase from Neisseria meningitidis MC58 | | 分子名称: | PHOSPHATE ION, Succinyl-diaminopimelate desuccinylase, ZINC ION | | 著者 | Nocek, B, Holz, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-02-27 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.
Biochemistry, 54, 2015
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6TXQ
 | | The high resolution structure of the FERM domain and helical linker of human moesin | | 分子名称: | ACETATE ION, Moesin | | 著者 | Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2020-01-14 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J.Biol.Chem., 299, 2023
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2RFL
 | | Crystal structure of the putative phosphohistidine phosphatase SixA from Agrobacterium tumefaciens | | 分子名称: | ACETIC ACID, GLYCEROL, Putative phosphohistidine phosphatase SixA, ... | | 著者 | Kim, Y, Binkowski, T, Xu, X, Edwards, A.M, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-10-01 | | 公開日 | 2007-10-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal Structure of the Putative Phosphohistidine Phosphatase SixA from
Agrobacterium tumefaciens.
To be Published
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6PAE
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1OAJ
 | | Active site copper and zinc ions modulate the quaternary structure of prokaryotic Cu,Zn superoxide dismutase | | 分子名称: | COPPER (II) ION, SUPEROXIDE DISMUTASE, ZINC ION | | 著者 | Cioni, P, Pesce, A, Rocca, B.M.D, Castelli, S, Falconi, M, Parrilli, L, Bolognesi, M, Strambini, G, Desideri, A. | | 登録日 | 2003-01-14 | | 公開日 | 2003-02-27 | | 最終更新日 | 2019-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Active-Site Copper and Zinc Ions Modulate the Quaternary Structure of Prokaryotic Cu,Zn Superoxide Dismutase
J.Mol.Biol., 326, 2003
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7YXP
 | | Crystal structure of WT AncGR2-LBD WT bound to dexamethasone and SHP coregulator fragment | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Ancestral Glucocorticoid Receptor2, DEXAMETHASONE, ... | | 著者 | Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P. | | 登録日 | 2022-02-16 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | | 主引用文献 | The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Nucleic Acids Res., 50, 2022
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1NMN
 | | Structure of yqgF from Escherichia coli, a hypothetical protein | | 分子名称: | Hypothetical protein yqgF | | 著者 | Galkin, A, Sarikaya, E, Krajewski, W, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) | | 登録日 | 2003-01-10 | | 公開日 | 2004-03-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of yqgF from Escherichia coli, a hypothetical protein
To be Published
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6I2B
 | | Crystal Structure of the Protein-Kinase A catalytic subunit from Cricetulus Griseus in complex with compounds RKp153 and RKp117 | | 分子名称: | UPF0418 protein FAM164A, [2-[(4-isoquinolin-5-ylsulfonyl-1,4-diazepan-1-yl)methyl]phenyl]boronic acid, beta-D-ribopyranose, ... | | 著者 | Mueller, J.M, Heine, A, Klebe, G. | | 登録日 | 2018-11-01 | | 公開日 | 2019-05-15 | | 最終更新日 | 2021-03-17 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage
Acs Omega, 2019
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6P6C
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7YXR
 | | Crystal structure of mutant AncGR2-LBD (Y545A) bound to dexamethasone and SHP coregulator fragment | | 分子名称: | Ancestral Glucocorticoid Receptor2, DEXAMETHASONE, FORMIC ACID, ... | | 著者 | Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P. | | 登録日 | 2022-02-16 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Nucleic Acids Res., 50, 2022
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