6K3N
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7WKU
| Structure of PDCoV Mpro in complex with an inhibitor | 分子名称: | N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, Peptidase C30 | 著者 | Wang, F.H, Yang, H.T. | 登録日 | 2022-01-11 | 公開日 | 2022-05-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals. Viruses, 14, 2022
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7WCY
| Crystal Structure of H-2Kb with Cryptosporidium parvum gp40/15 epitope | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | 著者 | Wang, Y.L, Gao, M.H, Zhang, L.X, Fan, S.H. | 登録日 | 2021-12-20 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structural Analyses of a Dominant Cryptosporidium parvum Epitope Presented by H-2K b Offer New Options To Combat Cryptosporidiosis. Mbio, 14, 2023
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7VUE
| Structural insight of the molecular mechanism of cilofexor bound to FXR | 分子名称: | 2-[3-[4-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-2-chloranyl-phenyl]-3-oxidanyl-azetidin-1-yl]pyridine-4-carboxylic acid, Bile acid receptor, Peptide from Nuclear receptor coactivator 2 | 著者 | Jiang, L, Chen, Y.C. | 登録日 | 2021-11-02 | 公開日 | 2022-03-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | Structural insight into the molecular mechanism of cilofexor binding to the farnesoid X receptor. Biochem.Biophys.Res.Commun., 595, 2022
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7XVN
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7Y3Y
| Crystal structure of BTG13 mutant (T299V) | 分子名称: | FE (III) ION, GLYCEROL, questin oxidase BTG13 | 著者 | Hou, X.D, Fu, K, Rao, Y.J. | 登録日 | 2022-06-13 | 公開日 | 2022-09-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Discovery of the Biosynthetic Pathway of Beticolin 1 Reveals a Novel Non-Heme Iron-Dependent Oxygenase for Anthraquinone Ring Cleavage. Angew.Chem.Int.Ed.Engl., 61, 2022
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7Y3X
| Crystal structure of BTG13 mutant (H58F) | 分子名称: | FE (III) ION, GLYCEROL, Questin oxidase | 著者 | Hou, X.D, Rao, Y.J. | 登録日 | 2022-06-13 | 公開日 | 2022-09-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Discovery of the Biosynthetic Pathway of Beticolin 1 Reveals a Novel Non-Heme Iron-Dependent Oxygenase for Anthraquinone Ring Cleavage. Angew.Chem.Int.Ed.Engl., 61, 2022
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7Y3W
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7X4B
| Crystal Structure of An Anti-CRISPR Protein | 分子名称: | Anti-CRISPR protein (AcrIIC1), SULFATE ION | 著者 | Hu, J, Zhang, S, Gao, J.Y, Liu, X, Liu, J. | 登録日 | 2022-03-02 | 公開日 | 2022-10-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1. Nat Commun, 13, 2022
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8GL6
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8GLJ
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8GLK
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8GLN
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8GL8
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8GLM
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8JMT
| Structure of the adhesion GPCR ADGRL3 in the apo state | 分子名称: | Adhesion G protein-coupled receptor L3,Soluble cytochrome b562 | 著者 | Tao, Y, Guo, Q, He, B, Zhong, Y. | 登録日 | 2023-06-05 | 公開日 | 2023-09-06 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
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8JJ8
| Cryo-EM structure of the beta2AR-mBRIL/1b3 Fab/Glue complex with a partial agonist | 分子名称: | Beta-2 adrenergic receptor,Soluble cytochrome b562, ~{N}-[5-[(1~{R})-2-[[(2~{R})-1-(4-methoxyphenyl)propan-2-yl]amino]-1-oxidanyl-ethyl]-2-oxidanyl-phenyl]methanamide | 著者 | He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. | 登録日 | 2023-05-29 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
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8JJL
| cryo-EM structure of the beta2-AR-mBRIL/1b3 Fab/Glue complex with a full agonist | 分子名称: | Beta-2 adrenergic receptor,Soluble cytochrome b562, Olodaterol | 著者 | He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. | 登録日 | 2023-05-30 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
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8J7E
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8JJO
| Cryo-EM structure of the beta2AR-mBRIL/1b3 Fab/Glue complex with an antagonist | 分子名称: | (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol, Beta-2 adrenergic receptor,Beta-2 adrenergic receptor,Soluble cytochrome b562 | 著者 | He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. | 登録日 | 2023-05-31 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
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7DNJ
| K63-polyUb MDA5CARDs complex | 分子名称: | Interferon-induced helicase C domain-containing protein 1, Ubiquitin | 著者 | Song, B, Chen, Y, Luo, D.H, Zheng, J. | 登録日 | 2020-12-09 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains. Immunity, 54, 2021
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7DNI
| MDA5 CARDs-MAVS CARD polyUb complex | 分子名称: | Interferon-induced helicase C domain-containing protein 1, Mitochondrial antiviral-signaling protein, Ubiquitin | 著者 | Song, B, Chen, Y, Luo, D.H, Zheng, J. | 登録日 | 2020-12-09 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains. Immunity, 54, 2021
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7DN9
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7DN8
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7C4O
| Solution structure of the Orange domain from human protein HES1 | 分子名称: | Transcription factor HES-1 | 著者 | Fan, J.S, Nayak, A, Swaminathan, K. | 登録日 | 2020-05-18 | 公開日 | 2021-05-19 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Induction of Transcriptional Inhibitor Hairy and Enhancer of Split Homolog-1 and the Related Repression of Tumor-Suppressor Thioredoxin-Interacting Protein Are Important Components of Cell-Transformation Program Imposed by Oncogenic Kinase Nucleophosmin-Anaplastic Lymphoma Kinase. Am J Pathol, 2022
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