7WKU
Structure of PDCoV Mpro in complex with an inhibitor
Summary for 7WKU
Entry DOI | 10.2210/pdb7wku/pdb |
Related PRD ID | PRD_002214 |
Descriptor | Peptidase C30, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE (3 entities in total) |
Functional Keywords | virus, viral protease, drug design, inhibitor, broad-spectrum antivirals, viral protein |
Biological source | Porcine deltacoronavirus More |
Total number of polymer chains | 12 |
Total formula weight | 212101.30 |
Authors | Wang, F.H.,Yang, H.T. (deposition date: 2022-01-11, release date: 2022-05-25, Last modification date: 2023-11-29) |
Primary citation | Wang, F.,Chen, C.,Wang, Z.,Han, X.,Shi, P.,Zhou, K.,Liu, X.,Xiao, Y.,Cai, Y.,Huang, J.,Zhang, L.,Yang, H. The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals. Viruses, 14:-, 2022 Cited by PubMed: 35336895DOI: 10.3390/v14030486 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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