2KBF
 
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2F90
 | | Crystal structure of bisphosphoglycerate mutase in complex with 3-phosphoglycerate and AlF4- | | 分子名称: | 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, TETRAFLUOROALUMINATE ION | | 著者 | Wang, Y, Liu, L, Wei, Z, Gong, W. | | 登録日 | 2005-12-05 | | 公開日 | 2006-10-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase
J.Biol.Chem., 281, 2006
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3BHK
 | | Crystal structure of R49K mutant of monomeric sarcosine oxidase crystallized in phosphate as precipitant | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Hassan-Abdallah, A, Zhao, G, Chen, Z, Mathews, F.S, Jorns, M.S. | | 登録日 | 2007-11-28 | | 公開日 | 2008-02-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Arginine 49 is a bifunctional residue important in catalysis and biosynthesis of monomeric sarcosine oxidase: a context-sensitive model for the electrostatic impact of arginine to lysine mutations.
Biochemistry, 47, 2008
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1M15
 | | Transition state structure of arginine kinase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ARGININE, MAGNESIUM ION, ... | | 著者 | Yousef, M.S, Fabiola, F, Gattis, J.L, Somasundaram, T, Chapman, M.S. | | 登録日 | 2002-06-17 | | 公開日 | 2002-12-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Refinement of the arginine kinase transition-state analogue complex at 1.2 A resolution: mechanistic insights.
Acta Crystallogr.,Sect.D, 58, 2002
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5K7X
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3BHF
 | | Crystal structure of R49K mutant of Monomeric Sarcosine Oxidase crystallized in PEG as precipitant | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Monomeric sarcosine oxidase | | 著者 | Hassan-Abdallah, A, Zhao, G, Chen, Z, Mathews, F.S, Jorns, M.S. | | 登録日 | 2007-11-28 | | 公開日 | 2008-02-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Arginine 49 is a bifunctional residue important in catalysis and biosynthesis of monomeric sarcosine oxidase: a context-sensitive model for the electrostatic impact of arginine to lysine mutations.
Biochemistry, 47, 2008
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4XT9
 | | RORgamma (263-509) complexed with GSK2435341A and SRC2 | | 分子名称: | LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, N-[4-(2,5-dichlorophenyl)-5-phenyl-1,3-thiazol-2-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide, Nuclear receptor ROR-gamma, ... | | 著者 | Wang, Y, Ma, Y. | | 登録日 | 2015-01-23 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent ROR gamma t inverse agonists
Bioorg.Med.Chem., 23, 2015
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6MEV
 | | Structure of JMJD6 bound to Mono-Methyl Arginine. | | 分子名称: | (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, 2-OXOGLUTARIC ACID, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, ... | | 著者 | Lee, S, Zhang, G. | | 登録日 | 2018-09-07 | | 公開日 | 2019-09-18 | | 最終更新日 | 2020-04-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes.
Elife, 9, 2020
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2H4X
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2H5E
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7FAP
 | | Structure of VAR2CSA-CSA 3D7 | | 分子名称: | 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-3)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, Erythrocyte membrane protein 1, PfEMP1 | | 著者 | Wang, L, Wang, Z. | | 登録日 | 2021-07-07 | | 公開日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum.
Cell Discov, 7, 2021
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2H4Z
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5E7R
 | | Crystal structure of TL10-81 bound to TAK1-TAB1 | | 分子名称: | 2-chloro-N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}acetamide, TAK1 kinase - TAB1 chimera fusion protein | | 著者 | Gurbani, D, Hunter, J.C, Tan, L, Chen, Z, Westover, K.D. | | 登録日 | 2015-10-13 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Structure-guided development of covalent TAK1 inhibitors.
Bioorg. Med. Chem., 25, 2017
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2HHJ
 | | Human bisphosphoglycerate mutase complexed with 2,3-bisphosphoglycerate (15 days) | | 分子名称: | (2R)-2,3-diphosphoglyceric acid, 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, ... | | 著者 | Wang, Y, Gong, W. | | 登録日 | 2006-06-28 | | 公開日 | 2006-10-24 | | 最終更新日 | 2016-07-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase.
J.Biol.Chem., 281, 2006
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3KWW
 | | Crystal structure of the 'restriction triad' mutant of HLA B*3508, beta-2-microglobulin and EBV peptide | | 分子名称: | ACETIC ACID, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Archbold, J.K, Tynan, F.E, Gras, S, Rossjohn, J. | | 登録日 | 2009-12-01 | | 公開日 | 2010-06-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability
Proc.Natl.Acad.Sci.USA, 2010
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5GNF
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5GQH
 | | Cryo-EM structure of PaeCas3-AcrF3 complex | | 分子名称: | CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, anti-CRISPR protein 3 | | 著者 | Zhang, X, Ma, J, Wang, Y, Wang, J. | | 登録日 | 2016-08-07 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
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5U6Q
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7EAX
 | | Crystal complex of p53-V272M and antimony ion | | 分子名称: | ANTIMONY (III) ION, Cellular tumor antigen p53, ZINC ION | | 著者 | Lu, M, Tang, Y. | | 登録日 | 2021-03-08 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations.
Cell Rep, 39, 2022
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7BV7
 | | INTS3 complexed with INTS6 | | 分子名称: | Integrator complex subunit 3, Integrator complex subunit 6 | | 著者 | Jia, Y, Bharath, S.R, Song, H. | | 登録日 | 2020-04-09 | | 公開日 | 2021-07-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the INTS3/INTS6 complex reveals the functional importance of INTS3 dimerization in DSB repair.
Cell Discov, 7, 2021
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3MGO
 | | Crystal structure of a H5-specific CTL epitope derived from H5N1 influenza virus in complex with HLA-A*0201 | | 分子名称: | 10-meric peptide from Hemagglutinin, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Sun, Y, Liu, J, Yang, M, Gao, F, Zhou, J, Kitamura, Y. | | 登録日 | 2010-04-07 | | 公開日 | 2010-05-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.297 Å) | | 主引用文献 | Identification and structural definition of H5-specific CTL epitopes restricted by HLA-A*0201 derived from the H5N1 subtype of influenza A viruses
J.Gen.Virol., 91, 2010
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5U1R
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7CBY
 | | Structure of FOXG1 DNA binding domain bound to DBE2 DNA site | | 分子名称: | DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), ... | | 著者 | Dai, S.Y, Li, J, Chen, Y.H. | | 登録日 | 2020-06-15 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.646 Å) | | 主引用文献 | Structural Basis for DNA Recognition by FOXG1 and the Characterization of Disease-causing FOXG1 Mutations.
J.Mol.Biol., 432, 2020
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7D57
 | | C-Src in complex with FIIN-2 | | 分子名称: | N-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)propanamide, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION | | 著者 | Chen, Y.H, Qu, L.Z. | | 登録日 | 2020-09-25 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | | 主引用文献 | Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors
Commun Chem, 5, 2022
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7D5O
 | | C-Src in complex with TAS-120 | | 分子名称: | 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one, Proto-oncogene tyrosine-protein kinase Src | | 著者 | Qu, L.Z, Chen, Y.H. | | 登録日 | 2020-09-27 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors
Commun Chem, 5, 2022
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