3Q9H
| LVFFA segment from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold | 分子名称: | 1,4-BUTANEDIOL, Cyclic pseudo-peptide LVFFA(ORN)(HAO)LK(ORN), GLYCEROL, ... | 著者 | Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J. | 登録日 | 2011-01-07 | 公開日 | 2011-06-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics. J.Am.Chem.Soc., 133, 2011
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6ISL
| SnoaL-like cyclase XimE with its product xiamenmycin B | 分子名称: | (2R,3S)-2-methyl-2-(4-methylpent-3-enyl)-3-oxidanyl-3,4-dihydrochromene-6-carboxylic acid, XimE, SnoaL-like domain protein | 著者 | He, B, Zhou, T, Bu, X, Weng, J, Xu, J, Lin, S, Zheng, J, Zhao, Y, Xu, M. | 登録日 | 2018-11-16 | 公開日 | 2019-11-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Enzymatic Pyran Formation Involved in Xiamenmycin Biosynthesis Acs Catalysis, 9, 2019
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6ISK
| SnoaL-like cyclase XimE | 分子名称: | 1,2-ETHANEDIOL, MALONIC ACID, XimE, ... | 著者 | He, B, Zhou, T, Bu, X, Weng, J, Xu, J, Lin, S, Zheng, J, Zhao, Y, Xu, M. | 登録日 | 2018-11-16 | 公開日 | 2019-11-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Enzymatic Pyran Formation Involved in Xiamenmycin Biosynthesis Acs Catalysis, 9, 2019
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6KJ7
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6KJ9
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6KJ8
| E. coli ATCase holoenzyme mutant - G166P (catalytic chain) | 分子名称: | Aspartate carbamoyltransferase catalytic subunit, Aspartate carbamoyltransferase regulatory chain, ZINC ION | 著者 | Lei, Z, Zheng, J, Jia, Z.C. | 登録日 | 2019-07-22 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.011 Å) | 主引用文献 | New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development. Febs J., 287, 2020
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6KJA
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8H8C
| Type VI secretion system effector RhsP in its post-autoproteolysis and dimeric form | 分子名称: | C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein | 著者 | Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. | 登録日 | 2022-10-22 | 公開日 | 2023-01-18 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
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8H8B
| Type VI secretion system effector RhsP in its pre-autoproteolysis and monomeric form | 分子名称: | Putative Rhs-family protein | 著者 | Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. | 登録日 | 2022-10-22 | 公開日 | 2023-01-18 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
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8H8A
| Type VI secretion system effector RhsP in its post-autoproteolysis and monomeric form | 分子名称: | C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein | 著者 | Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. | 登録日 | 2022-10-22 | 公開日 | 2023-01-18 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
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8YL5
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5AYW
| Structure of a membrane complex | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | 著者 | Huang, Y, Han, L, Zheng, J. | 登録日 | 2015-09-14 | 公開日 | 2016-02-24 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.555 Å) | 主引用文献 | Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins Nat.Struct.Mol.Biol., 23, 2016
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6IIH
| crystal structure of mitochondrial calcium uptake 2(MICU2) | 分子名称: | CALCIUM ION, Endolysin,Calcium uptake protein 2, mitochondrial | 著者 | Shen, Q, Wu, W, Zheng, J, Jia, Z. | 登録日 | 2018-10-06 | 公開日 | 2019-08-14 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.958 Å) | 主引用文献 | The crystal structure of MICU2 provides insight into Ca2+binding and MICU1-MICU2 heterodimer formation. Embo Rep., 20, 2019
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6IYO
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6J0U
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6IYT
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6K5L
| The crystal structure of isocitrate dehydrogenase kinase/phosphatase wtih two Mn2+ from E. coli | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ... | 著者 | Zhang, X, Lei, Z, Zheng, J, Jia, Z. | 登録日 | 2019-05-29 | 公開日 | 2019-07-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Characterization of metal binding of bifunctional kinase/phosphatase AceK and implication in activity modulation. Sci Rep, 9, 2019
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6IYR
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6KJB
| wild-type apo-form E. coli ATCase holoenzyme with an unusual open conformation of R167 | 分子名称: | Aspartate carbamoyltransferase catalytic subunit, Aspartate carbamoyltransferase regulatory chain, ZINC ION | 著者 | Wang, N, Lei, Z, Zheng, J, Jia, Z.C. | 登録日 | 2019-07-22 | 公開日 | 2020-06-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Conformational Plasticity of the Active Site Entrance inE. coliAspartate Transcarbamoylase and Its Implication in Feedback Regulation. Int J Mol Sci, 21, 2020
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8IA9
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8IAA
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8HVR
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7VX0
| The structure of GdmN complex with ATP | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, FE (III) ION, ... | 著者 | Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L. | 登録日 | 2021-11-12 | 公開日 | 2022-11-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies. Nat Commun, 13, 2022
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7VZN
| The structure of GdmN in complex with carbamoyl adenylate intermediate and 20-O-methyl-19-chloroproansamitocin | 分子名称: | (5~{S},6~{E},8~{S},9~{S},12~{R},15~{E})-21-chloranyl-12,20-dimethoxy-6,8,16-trimethyl-5,9-bis(oxidanyl)-2-azabicyclo[16.3.1]docosa-1(21),6,15,18(22),19-pentaene-3,11-dione, 1,2-ETHANEDIOL, 5'-O-[(S)-(carbamoyloxy)(hydroxy)phosphoryl]adenosine, ... | 著者 | Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L. | 登録日 | 2021-11-16 | 公開日 | 2022-11-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies. Nat Commun, 13, 2022
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7VZQ
| The structure of GdmN V24Y/G157A/R158A/G188R mutant in complex with carbamoyl adenylate intermediate | 分子名称: | 1,2-ETHANEDIOL, 5'-O-[(S)-(carbamoyloxy)(hydroxy)phosphoryl]adenosine, CHLORIDE ION, ... | 著者 | Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L. | 登録日 | 2021-11-16 | 公開日 | 2022-11-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies. Nat Commun, 13, 2022
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