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8J54
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Crystal structure of RXR/DR2 complex
分子名称: DNA (5'-D(*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Retinoic acid receptor RXR, ...
著者Chen, Y, Jiang, L.
登録日2023-04-21
公開日2024-01-17
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma.
Structure, 32, 2024
6OSY
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BU of 6osy by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
分子名称: 0PV-a.01 Heavy, 0PV-a.01 Light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorman, J, Kwong, P.D.
登録日2019-05-02
公開日2019-07-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6OT1
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BU of 6ot1 by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
分子名称: 0PV-b.01 heavy, 0PV-b.01 light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorman, J, Kwong, P.D.
登録日2019-05-02
公開日2019-08-07
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6M2Z
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BU of 6m2z by Molmil
Crystal structure of a formolase, BFD variant M3 from Pseudomonas putida
分子名称: Benzoylformate decarboxylase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
著者Wei, H.L, Liu, W.D, Li, T.Z, Zhu, L.L.
登録日2020-03-02
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Totally atom-economical synthesis of lactic acid from formaldehyde: combined bio-carboligation and chemo-rearrangement without the isolation of intermediate.
Green Chem, 22, 2020
6M2Y
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BU of 6m2y by Molmil
Crystal structure of a formolase, BFD variant M6 from Pseudomonas putida
分子名称: Benzoylformate decarboxylase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
著者Wei, H.L, Liu, W.D, Li, T.Z, Zhu, L.L.
登録日2020-03-02
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Totally atom-economical synthesis of lactic acid from formaldehyde: combined bio-carboligation and chemo-rearrangement without the isolation of intermediate.
Green Chem, 22, 2020
5H9D
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BU of 5h9d by Molmil
Crystal structure of Heptaprenyl Diphosphate Synthase from Staphylococcus aureus
分子名称: C-terminal peptide from Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 family protein, Farnesyl pyrophosphate synthetase, Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 family protein, ...
著者Wei, H.L, Liu, W.D, Zheng, Y.Y, Ko, T.P, Chen, C.C, Guo, R.T.
登録日2015-12-28
公開日2016-12-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structure, Function, and Inhibition of Staphylococcus aureus Heptaprenyl Diphosphate Synthase
ChemMedChem, 11, 2016
7W1I
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BU of 7w1i by Molmil
Crystal structure of carboxylesterase mutant from Thermobifida fusca with C8X and C9C
分子名称: 4-(2-hydroxyethyloxycarbonyl)benzoic acid, Carboxylesterase, bis(2-hydroxyethyl) benzene-1,4-dicarboxylate
著者Han, X, Gerlis, H, Li, Z, Gao, J, Wei, R, Liu, W.
登録日2021-11-19
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization
Acs Catalysis, 12, 2022
7W1K
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BU of 7w1k by Molmil
Crystal structure of carboxylesterase from Thermobifida fusca
分子名称: Carboxylesterase
著者Han, X, Gerlis, H, Li, Z, Gao, J, Wei, R, Liu, W.
登録日2021-11-19
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization
Acs Catalysis, 12, 2022
7W1J
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BU of 7w1j by Molmil
Crystal structure of carboxylesterase from Thermobifida fusca with J1K
分子名称: 4-(2-hydroxyethylcarbamoyl)benzoic acid, Carboxylesterase
著者Han, X, Gerlis, H, Li, Z, Gao, J, Wei, R, Liu, W.
登録日2021-11-19
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization
Acs Catalysis, 12, 2022
7W1L
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BU of 7w1l by Molmil
Crystal structure of carboxylesterase mutant from Thermobifida fusca with C8X
分子名称: Carboxylesterase, bis(2-hydroxyethyl) benzene-1,4-dicarboxylate
著者Han, X, Gerlis, H, Li, Z, Gao, J, Wei, R, Liu, W.
登録日2021-11-19
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization
Acs Catalysis, 12, 2022
6L6L
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BU of 6l6l by Molmil
Structural basis of NR4A2 homodimers binding to selective Nur-responsive elements
分子名称: DNA (5'-D(*AP*AP*AP*GP*GP*TP*CP*AP*AP*AP*CP*TP*GP*TP*GP*AP*CP*CP*TP*AP*T)-3'), DNA (5'-D(P*TP*AP*TP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*TP*TP*GP*AP*CP*CP*TP*T)-3'), Nuclear receptor related 1, ...
著者Jiang, L, Chen, Y.
登録日2019-10-29
公開日2019-11-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.781 Å)
主引用文献Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements.
J.Biol.Chem., 294, 2019
7XVN
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BU of 7xvn by Molmil
Structural basis for DNA recognition feature of retinoid-related orphan receptors
分子名称: DNA (5'-D(P*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Nuclear receptor ROR-gamma, ...
著者Chen, Y, Jiang, L.
登録日2022-05-24
公開日2023-11-29
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma.
Structure, 32, 2024
6L6Q
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BU of 6l6q by Molmil
Structural basis of NR4A2 homodimers binding to selective Nur-responsive elements
分子名称: DNA (5'-D(P*AP*GP*TP*GP*AP*CP*CP*TP*TP*TP*AP*AP*AP*GP*GP*TP*CP*AP*CP*T)-3'), Nuclear receptor related 1, ZINC ION
著者Jiang, L, Chen, Y.
登録日2019-10-29
公開日2019-11-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements.
J.Biol.Chem., 294, 2019
6LC1
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BU of 6lc1 by Molmil
Structural basis of NR4A1 bound to the human pituitary proopiomelanocortin gene promoter
分子名称: DNA, DNA (25-MER), Nuclear receptor subfamily 4 group A member 1, ...
著者Jiang, L, Chen, Y.
登録日2019-11-16
公開日2019-12-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Structural basis of NR4A1 bound to the human pituitary proopiomelanocortin gene promoter.
Biochem.Biophys.Res.Commun., 523, 2020
6XOS
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BU of 6xos by Molmil
CryoEM structure of human presequence protease in partial open state 1
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOU
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BU of 6xou by Molmil
CryoEM structure of human presequence protease in open state
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOV
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BU of 6xov by Molmil
CryoEM structure of human presequence protease in partial closed state 1
分子名称: Amyloid-beta precursor protein, Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOT
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BU of 6xot by Molmil
CryoEM structure of human presequence protease in partial open state 2
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6VAC
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BU of 6vac by Molmil
Mouse retromer (VPS26/VPS35/VPS29) heterotrimer
分子名称: Vacuolar protein sorting-associated protein 26A, Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35
著者Kendall, A.K, Jackson, L.P.
登録日2019-12-17
公開日2020-02-19
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Mammalian Retromer Is an Adaptable Scaffold for Cargo Sorting from Endosomes.
Structure, 28, 2020
7XUZ
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BU of 7xuz by Molmil
Crystal structure of a HDAC4-MEF2A-DNA ternary complex
分子名称: DNA (5'-D(*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*T)-3'), DNA (5'-D(P*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*A)-3'), Histone deacetylase 4, ...
著者Dai, S.Y, Guo, L, Dey, R, Guo, M, Bates, D, Cayford, J, Chen, X.J, Wei, X.D, Chen, L, Chen, Y.H.
登録日2022-05-20
公開日2023-11-29
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.591 Å)
主引用文献Structural insights into the HDAC4-MEF2A-DNA complex and its implication in long-range transcriptional regulation.
Nucleic Acids Res., 52, 2024
8K79
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BU of 8k79 by Molmil
Crystal structure of c-SRC kinase domain bound by TPX-0022
分子名称: Elzovantinib, Proto-oncogene tyrosine-protein kinase Src
著者Qu, L.Z, Chen, Y.H.
登録日2023-07-26
公開日2024-07-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insight into the macrocyclic inhibitor TPX-0022 of c-Met and c-Src.
Comput Struct Biotechnol J, 21, 2023
8K78
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BU of 8k78 by Molmil
Crystal structure of cMET kinase domain bound by TPX-0022
分子名称: Elzovantinib, Hepatocyte growth factor receptor
著者Qu, L.Z, Chen, Y.H.
登録日2023-07-26
公開日2024-07-31
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural insight into the macrocyclic inhibitor TPX-0022 of c-Met and c-Src.
Comput Struct Biotechnol J, 21, 2023
6GY1
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BU of 6gy1 by Molmil
rat COMT in complex with inhibitor
分子名称: 7-fluoranyl-5-(4-methylphenyl)sulfonyl-quinolin-8-ol, Catechol O-methyltransferase, DIMETHYL SULFOXIDE, ...
著者Schulze, M.-S.
登録日2018-06-27
公開日2018-10-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase.
J. Med. Chem., 61, 2018
6MQC
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BU of 6mqc by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-c.01 in complex with FP (residue 512-519)
分子名称: 0PV-C.01 antibody Fab heavy chain, 0PV-C.01 antibody Fab light chain, HIV fusion peptide residue 512-519
著者Xu, K, Wang, Y, Kwong, P.D.
登録日2018-10-09
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MPH
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BU of 6mph by Molmil
Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DF1W-a.01 Light chain, ...
著者Acharya, P, Xu, K, Kwong, P.D.
登録日2018-10-06
公開日2019-07-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019

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件を2024-10-09に公開中

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