3WEH
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![BU of 3weh by Molmil](/molmil-images/mine/3weh) | Crystal structure of the human squalene synthase in complex with presqualene pyrophosphate | 分子名称: | MAGNESIUM ION, Squalene synthase, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | 登録日 | 2013-07-07 | 公開日 | 2014-02-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structural insights into the catalytic mechanism of human squalene synthase. Acta Crystallogr.,Sect.D, 70, 2014
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3WEK
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![BU of 3wek by Molmil](/molmil-images/mine/3wek) | Crystal structure of the human squalene synthase F288L mutant in complex with presqualene pyrophosphate | 分子名称: | MAGNESIUM ION, Squalene synthase, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | 登録日 | 2013-07-07 | 公開日 | 2014-02-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural insights into the catalytic mechanism of human squalene synthase. Acta Crystallogr.,Sect.D, 70, 2014
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3W52
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![BU of 3w52 by Molmil](/molmil-images/mine/3w52) | Zinc-dependent bifunctional nuclease | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Endonuclease 2, ... | 著者 | Chou, T.L, Ko, T.P, Ko, C.Y, Shaw, J.F, Wang, A.H.J. | 登録日 | 2013-01-18 | 公開日 | 2013-04-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Mechanistic insights to catalysis by a zinc-dependent bi-functional nuclease from Arabidopsis thaliana BIOCATAL AGRIC BIOTECHNOL, 2013
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3WEF
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![BU of 3wef by Molmil](/molmil-images/mine/3wef) | Crystal structure of the human squalene synthase in complex with farnesyl thiopyrophosphate | 分子名称: | S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Squalene synthase | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | 登録日 | 2013-07-07 | 公開日 | 2014-02-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural insights into the catalytic mechanism of human squalene synthase. Acta Crystallogr.,Sect.D, 70, 2014
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3VJA
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![BU of 3vja by Molmil](/molmil-images/mine/3vja) | Crystal structure of the human squalene synthase | 分子名称: | NICKEL (II) ION, Squalene synthase | 著者 | Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J. | 登録日 | 2011-10-14 | 公開日 | 2012-04-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase J.Biol.Chem., 287, 2012
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3WEJ
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![BU of 3wej by Molmil](/molmil-images/mine/3wej) | Crystal structure of the human squalene synthase F288A mutant in complex with presqualene pyrophosphate | 分子名称: | MAGNESIUM ION, Squalene synthase, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | 登録日 | 2013-07-07 | 公開日 | 2014-02-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into the catalytic mechanism of human squalene synthase. Acta Crystallogr.,Sect.D, 70, 2014
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3WEG
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![BU of 3weg by Molmil](/molmil-images/mine/3weg) | Crystal structure of the human squalene synthase in complex with farnesyl thiopyrophosphate and magnesium ion | 分子名称: | MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Squalene synthase | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | 登録日 | 2013-07-07 | 公開日 | 2014-02-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural insights into the catalytic mechanism of human squalene synthase. Acta Crystallogr.,Sect.D, 70, 2014
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4QI1
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![BU of 4qi1 by Molmil](/molmil-images/mine/4qi1) | Crystal structure of H. walsbyi bacteriorhodopsin | 分子名称: | Bacteriorhodopsin-I, GLYCEROL, RETINAL, ... | 著者 | Wang, A.H.J, Hsu, M.F, Yang, C.S, Fu, H.Y. | 登録日 | 2014-05-30 | 公開日 | 2015-07-29 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural and Functional Studies of a Newly Grouped Haloquadratum walsbyi Bacteriorhodopsin Reveal the Acid-resistant Light-driven Proton Pumping Activity. J. Biol. Chem., 290, 2015
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3X0U
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![BU of 3x0u by Molmil](/molmil-images/mine/3x0u) | Crystal structure of PirB | 分子名称: | Uncharacterized protein | 著者 | Wang, H.C, Ko, T.P, Wang, A.H.J, Lo, C.F. | 登録日 | 2014-10-22 | 公開日 | 2015-08-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin. Proc.Natl.Acad.Sci.USA, 112, 2015
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2DF7
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![BU of 2df7 by Molmil](/molmil-images/mine/2df7) | Crystal structure of infectious bursal disease virus VP2 subviral particle | 分子名称: | CALCIUM ION, CHLORIDE ION, structural polyprotein VP2 | 著者 | Ko, T.P, Lee, C.C, Wang, M.Y, Wang, A.H. | 登録日 | 2006-02-27 | 公開日 | 2006-06-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6A resolution: Implications in virion assembly and immunogenicity. J.Struct.Biol., 155, 2006
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1KUF
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![BU of 1kuf by Molmil](/molmil-images/mine/1kuf) | High-resolution Crystal Structure of a Snake Venom Metalloproteinase from Taiwan Habu | 分子名称: | CADMIUM ION, metalloproteinase | 著者 | Huang, K.F, Chiou, S.H, Ko, T.P, Yuann, J.M, Wang, A.H.J. | 登録日 | 2002-01-21 | 公開日 | 2002-07-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The 1.35 A structure of cadmium-substituted TM-3, a snake-venom metalloproteinase from Taiwan habu: elucidation of a TNFalpha-converting enzyme-like active-site structure with a distorted octahedral geometry of cadmium. Acta Crystallogr.,Sect.D, 58, 2002
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1KUK
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![BU of 1kuk by Molmil](/molmil-images/mine/1kuk) | Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with pEKW. | 分子名称: | CADMIUM ION, EKW, metalloproteinase | 著者 | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | 登録日 | 2002-01-22 | 公開日 | 2002-07-10 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues. Eur.J.Biochem., 269, 2002
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1KUG
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![BU of 1kug by Molmil](/molmil-images/mine/1kug) | Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with its endogenous inhibitor pENW | 分子名称: | CADMIUM ION, ENW, metalloproteinase | 著者 | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | 登録日 | 2002-01-22 | 公開日 | 2002-07-10 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues. Eur.J.Biochem., 269, 2002
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3LEE
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![BU of 3lee by Molmil](/molmil-images/mine/3lee) | |
7DOH
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![BU of 7doh by Molmil](/molmil-images/mine/7doh) | |
3IWZ
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![BU of 3iwz by Molmil](/molmil-images/mine/3iwz) | The c-di-GMP Responsive Global Regulator CLP Links Cell-Cell Signaling to Virulence Gene Expression in Xanthomonas campestris | 分子名称: | Catabolite activation-like protein | 著者 | Chin, K.H, Tu, Z.L, Tseng, Y.H, Dow, J.M, Wang, A.H.J, Chou, S.H. | 登録日 | 2009-09-03 | 公開日 | 2009-12-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The cAMP receptor-like protein CLP is a novel c-di-GMP receptor linking cell-cell signaling to virulence gene expression in Xanthomonas campestris. J.Mol.Biol., 396, 2010
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1JP3
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![BU of 1jp3 by Molmil](/molmil-images/mine/1jp3) | Structure of E.coli undecaprenyl pyrophosphate synthase | 分子名称: | 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, undecaprenyl pyrophosphate synthase | 著者 | Ko, T.P, Chen, Y.K, Robinson, H, Tsai, P.C, Gao, Y.G, Chen, A.P.C, Wang, A.H.J, Liang, P.H. | 登録日 | 2001-07-31 | 公開日 | 2001-08-15 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis. J.Biol.Chem., 276, 2001
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1KUI
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![BU of 1kui by Molmil](/molmil-images/mine/1kui) | Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with pEQW. | 分子名称: | CADMIUM ION, EQW, metalloproteinase | 著者 | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | 登録日 | 2002-01-22 | 公開日 | 2002-07-10 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues. Eur.J.Biochem., 269, 2002
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3LGZ
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![BU of 3lgz by Molmil](/molmil-images/mine/3lgz) | Crystal structure of dehydrosqualene synthase Y129A from S. aureus complexed with presqualene pyrophosphate | 分子名称: | Dehydrosqualene synthase, MAGNESIUM ION, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | 著者 | Lin, F.-Y, Liu, Y.-L, Liu, C.-I, Wang, A.H.J, Oldfield, E. | 登録日 | 2010-01-21 | 公開日 | 2010-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Mechanism of action and inhibition of dehydrosqualene synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
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5AYR
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![BU of 5ayr by Molmil](/molmil-images/mine/5ayr) | The crystal structure of SAUGI/human UDG complex | 分子名称: | MAGNESIUM ION, Uncharacterized protein, Uracil-DNA glycosylase | 著者 | Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J. | 登録日 | 2015-09-02 | 公開日 | 2016-06-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase. Nucleic Acids Res., 44, 2016
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5AYS
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![BU of 5ays by Molmil](/molmil-images/mine/5ays) | Crystal structure of SAUGI/HSV UDG complex | 分子名称: | Uncharacterized protein, Uracil-DNA glycosylase | 著者 | Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J. | 登録日 | 2015-09-02 | 公開日 | 2016-06-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase. Nucleic Acids Res., 44, 2016
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3B01
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![BU of 3b01 by Molmil](/molmil-images/mine/3b01) | Crystal structure of the laminarinase catalytic domain from Thermotoga maritima MSB8 | 分子名称: | CALCIUM ION, CHLORIDE ION, Laminarinase, ... | 著者 | Jeng, W.Y, Wang, N.C, Wang, A.H.J. | 登録日 | 2011-06-03 | 公開日 | 2011-11-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: essential residues for beta-1,3 and beta-1,4 glucan selection. J.Biol.Chem., 286, 2011
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3AZX
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![BU of 3azx by Molmil](/molmil-images/mine/3azx) | Crystal structure of the laminarinase catalytic domain from Thermotoga maritima MSB8 | 分子名称: | CALCIUM ION, Laminarinase | 著者 | Jeng, W.Y, Wang, N.C, Wang, A.H.J. | 登録日 | 2011-06-03 | 公開日 | 2011-11-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: essential residues for beta-1,3 and beta-1,4 glucan selection. J.Biol.Chem., 286, 2011
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3AZZ
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![BU of 3azz by Molmil](/molmil-images/mine/3azz) | Crystal structure of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with gluconolactone | 分子名称: | CALCIUM ION, D-glucono-1,5-lactone, Laminarinase, ... | 著者 | Jeng, W.Y, Wang, N.C, Wang, A.H.J. | 登録日 | 2011-06-03 | 公開日 | 2011-11-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: essential residues for beta-1,3 and beta-1,4 glucan selection. J.Biol.Chem., 286, 2011
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3AZY
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![BU of 3azy by Molmil](/molmil-images/mine/3azy) | Crystal structure of the laminarinase catalytic domain from Thermotoga maritima MSB8 | 分子名称: | CALCIUM ION, Laminarinase, SULFATE ION | 著者 | Jeng, W.Y, Wang, N.C, Wang, A.H.J. | 登録日 | 2011-06-03 | 公開日 | 2011-11-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: essential residues for beta-1,3 and beta-1,4 glucan selection. J.Biol.Chem., 286, 2011
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