3WEH
 
 | | Crystal structure of the human squalene synthase in complex with presqualene pyrophosphate | | 分子名称: | MAGNESIUM ION, Squalene synthase, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | | 登録日 | 2013-07-07 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structural insights into the catalytic mechanism of human squalene synthase.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
3WEK
 | | Crystal structure of the human squalene synthase F288L mutant in complex with presqualene pyrophosphate | | 分子名称: | MAGNESIUM ION, Squalene synthase, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | | 登録日 | 2013-07-07 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural insights into the catalytic mechanism of human squalene synthase.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
3W52
 | | Zinc-dependent bifunctional nuclease | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Endonuclease 2, ... | | 著者 | Chou, T.L, Ko, T.P, Ko, C.Y, Shaw, J.F, Wang, A.H.J. | | 登録日 | 2013-01-18 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Mechanistic insights to catalysis by a zinc-dependent bi-functional nuclease from Arabidopsis thaliana
BIOCATAL AGRIC BIOTECHNOL, 2013
|
|
3WEF
 | | Crystal structure of the human squalene synthase in complex with farnesyl thiopyrophosphate | | 分子名称: | S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Squalene synthase | | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | | 登録日 | 2013-07-07 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural insights into the catalytic mechanism of human squalene synthase.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
3VJA
 | | Crystal structure of the human squalene synthase | | 分子名称: | NICKEL (II) ION, Squalene synthase | | 著者 | Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J. | | 登録日 | 2011-10-14 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
|
|
3WEJ
 | | Crystal structure of the human squalene synthase F288A mutant in complex with presqualene pyrophosphate | | 分子名称: | MAGNESIUM ION, Squalene synthase, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | | 登録日 | 2013-07-07 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into the catalytic mechanism of human squalene synthase.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
3WEG
 | | Crystal structure of the human squalene synthase in complex with farnesyl thiopyrophosphate and magnesium ion | | 分子名称: | MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Squalene synthase | | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | | 登録日 | 2013-07-07 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural insights into the catalytic mechanism of human squalene synthase.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
4QI1
 | | Crystal structure of H. walsbyi bacteriorhodopsin | | 分子名称: | Bacteriorhodopsin-I, GLYCEROL, RETINAL, ... | | 著者 | Wang, A.H.J, Hsu, M.F, Yang, C.S, Fu, H.Y. | | 登録日 | 2014-05-30 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and Functional Studies of a Newly Grouped Haloquadratum walsbyi Bacteriorhodopsin Reveal the Acid-resistant Light-driven Proton Pumping Activity.
J. Biol. Chem., 290, 2015
|
|
3X0U
 | | Crystal structure of PirB | | 分子名称: | Uncharacterized protein | | 著者 | Wang, H.C, Ko, T.P, Wang, A.H.J, Lo, C.F. | | 登録日 | 2014-10-22 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
2DF7
 | | Crystal structure of infectious bursal disease virus VP2 subviral particle | | 分子名称: | CALCIUM ION, CHLORIDE ION, structural polyprotein VP2 | | 著者 | Ko, T.P, Lee, C.C, Wang, M.Y, Wang, A.H. | | 登録日 | 2006-02-27 | | 公開日 | 2006-06-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6A resolution: Implications in virion assembly and immunogenicity.
J.Struct.Biol., 155, 2006
|
|
1KUF
 | | High-resolution Crystal Structure of a Snake Venom Metalloproteinase from Taiwan Habu | | 分子名称: | CADMIUM ION, metalloproteinase | | 著者 | Huang, K.F, Chiou, S.H, Ko, T.P, Yuann, J.M, Wang, A.H.J. | | 登録日 | 2002-01-21 | | 公開日 | 2002-07-03 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | The 1.35 A structure of cadmium-substituted TM-3, a snake-venom metalloproteinase from Taiwan habu: elucidation of a TNFalpha-converting enzyme-like active-site structure with a distorted octahedral geometry of cadmium.
Acta Crystallogr.,Sect.D, 58, 2002
|
|
1KUK
 | | Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with pEKW. | | 分子名称: | CADMIUM ION, EKW, metalloproteinase | | 著者 | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | | 登録日 | 2002-01-22 | | 公開日 | 2002-07-10 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues.
Eur.J.Biochem., 269, 2002
|
|
1KUG
 | | Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with its endogenous inhibitor pENW | | 分子名称: | CADMIUM ION, ENW, metalloproteinase | | 著者 | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | | 登録日 | 2002-01-22 | | 公開日 | 2002-07-10 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues.
Eur.J.Biochem., 269, 2002
|
|
3LEE
 | |
7DOH
 | |
3IWZ
 | | The c-di-GMP Responsive Global Regulator CLP Links Cell-Cell Signaling to Virulence Gene Expression in Xanthomonas campestris | | 分子名称: | Catabolite activation-like protein | | 著者 | Chin, K.H, Tu, Z.L, Tseng, Y.H, Dow, J.M, Wang, A.H.J, Chou, S.H. | | 登録日 | 2009-09-03 | | 公開日 | 2009-12-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The cAMP receptor-like protein CLP is a novel c-di-GMP receptor linking cell-cell signaling to virulence gene expression in Xanthomonas campestris.
J.Mol.Biol., 396, 2010
|
|
1JP3
 | | Structure of E.coli undecaprenyl pyrophosphate synthase | | 分子名称: | 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, undecaprenyl pyrophosphate synthase | | 著者 | Ko, T.P, Chen, Y.K, Robinson, H, Tsai, P.C, Gao, Y.G, Chen, A.P.C, Wang, A.H.J, Liang, P.H. | | 登録日 | 2001-07-31 | | 公開日 | 2001-08-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis.
J.Biol.Chem., 276, 2001
|
|
1KUI
 | | Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with pEQW. | | 分子名称: | CADMIUM ION, EQW, metalloproteinase | | 著者 | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | | 登録日 | 2002-01-22 | | 公開日 | 2002-07-10 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues.
Eur.J.Biochem., 269, 2002
|
|
3LGZ
 | | Crystal structure of dehydrosqualene synthase Y129A from S. aureus complexed with presqualene pyrophosphate | | 分子名称: | Dehydrosqualene synthase, MAGNESIUM ION, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | | 著者 | Lin, F.-Y, Liu, Y.-L, Liu, C.-I, Wang, A.H.J, Oldfield, E. | | 登録日 | 2010-01-21 | | 公開日 | 2010-12-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Mechanism of action and inhibition of dehydrosqualene synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
5AYR
 | | The crystal structure of SAUGI/human UDG complex | | 分子名称: | MAGNESIUM ION, Uncharacterized protein, Uracil-DNA glycosylase | | 著者 | Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J. | | 登録日 | 2015-09-02 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase.
Nucleic Acids Res., 44, 2016
|
|
5AYS
 | | Crystal structure of SAUGI/HSV UDG complex | | 分子名称: | Uncharacterized protein, Uracil-DNA glycosylase | | 著者 | Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J. | | 登録日 | 2015-09-02 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase.
Nucleic Acids Res., 44, 2016
|
|
3B01
 | | Crystal structure of the laminarinase catalytic domain from Thermotoga maritima MSB8 | | 分子名称: | CALCIUM ION, CHLORIDE ION, Laminarinase, ... | | 著者 | Jeng, W.Y, Wang, N.C, Wang, A.H.J. | | 登録日 | 2011-06-03 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: essential residues for beta-1,3 and beta-1,4 glucan selection.
J.Biol.Chem., 286, 2011
|
|
3AZX
 | | Crystal structure of the laminarinase catalytic domain from Thermotoga maritima MSB8 | | 分子名称: | CALCIUM ION, Laminarinase | | 著者 | Jeng, W.Y, Wang, N.C, Wang, A.H.J. | | 登録日 | 2011-06-03 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: essential residues for beta-1,3 and beta-1,4 glucan selection.
J.Biol.Chem., 286, 2011
|
|
3AZZ
 | | Crystal structure of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with gluconolactone | | 分子名称: | CALCIUM ION, D-glucono-1,5-lactone, Laminarinase, ... | | 著者 | Jeng, W.Y, Wang, N.C, Wang, A.H.J. | | 登録日 | 2011-06-03 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: essential residues for beta-1,3 and beta-1,4 glucan selection.
J.Biol.Chem., 286, 2011
|
|
3AZY
 | | Crystal structure of the laminarinase catalytic domain from Thermotoga maritima MSB8 | | 分子名称: | CALCIUM ION, Laminarinase, SULFATE ION | | 著者 | Jeng, W.Y, Wang, N.C, Wang, A.H.J. | | 登録日 | 2011-06-03 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: essential residues for beta-1,3 and beta-1,4 glucan selection.
J.Biol.Chem., 286, 2011
|
|
