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5YCL
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BU of 5ycl by Molmil
Crystal structure of HigBA complex from Shigella flexneri
分子名称: Antitoxin HigA, mRNA interferase HigB
著者Youn, W.S, Seok, S.H, Seo, M.D.
登録日2017-09-07
公開日2018-09-19
最終更新日2019-09-04
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Structural changes of antitoxin HigA from Shigella flexneri by binding of its cognate toxin HigB.
Int.J.Biol.Macromol., 130, 2019
5KU6
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BU of 5ku6 by Molmil
Crystal structure for the complex of human carbonic anhydrase IV and methazolamide
分子名称: ACETATE ION, Carbonic anhydrase 4, GLYCEROL, ...
著者Chen, Z, Waheed, A, Di Cera, E, Sly, W.S.
登録日2016-07-12
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur. Biophys. J., 47, 2018
3V3X
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BU of 3v3x by Molmil
Nitroxide Spin Labels in Protein GB1: N8/K28 Double Mutant
分子名称: ACETATE ION, GLYCEROL, Immunoglobulin G-binding protein G, ...
著者Cunningham, T.F, McGoff, M.S, Sengupta, I, Jaroniec, C.P, Horne, W.S, Saxena, S.K.
登録日2011-12-14
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献High-resolution structure of a protein spin-label in a solvent-exposed beta-sheet and comparison with DEER spectroscopy.
Biochemistry, 51, 2012
6AP0
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BU of 6ap0 by Molmil
Crystal structure of human FLASH N-terminal domain C54S/C83A (Crystal form 2)
分子名称: CASP8-associated protein 2
著者Aik, W.S, Tong, L.
登録日2017-08-16
公開日2017-11-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.581 Å)
主引用文献The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing.
PLoS ONE, 12, 2017
6ANO
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BU of 6ano by Molmil
Crystal structure of human FLASH N-terminal domain
分子名称: CASP8-associated protein 2
著者Aik, W.S, Tong, L.
登録日2017-08-14
公開日2017-11-15
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing.
PLoS ONE, 12, 2017
2DW6
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BU of 2dw6 by Molmil
Crystal structure of the mutant K184A of D-Tartrate Dehydratase from Bradyrhizobium japonicum complexed with Mg++ and D-tartrate
分子名称: Bll6730 protein, D(-)-TARTARIC ACID, L(+)-TARTARIC ACID, ...
著者Fedorov, A.A, Fedorov, E.V, Yew, W.S, Wood, B.M, Gerlt, J.A, Almo, S.C.
登録日2006-08-07
公開日2006-12-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Evolution of Enzymatic Activities in the Enolase Superfamily: d-Tartrate Dehydratase from Bradyrhizobium japonicum
Biochemistry, 45, 2006
6CU7
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BU of 6cu7 by Molmil
Alpha Synuclein fibril formed by full length protein - Rod Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
6BTH
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BU of 6bth by Molmil
Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with 2-arachidonoylglycerol (2-AG)
分子名称: 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, DI(HYDROXYETHYL)ETHER, Retinol-binding protein 2
著者Silvaroli, J.A, Blaner, W.S, Lodowski, D.T, Golczak, M.
登録日2017-12-06
公開日2018-12-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight.
Sci Adv, 6, 2020
3ZXJ
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BU of 3zxj by Molmil
Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, HIAXHD3, ...
著者McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J.
登録日2011-08-11
公開日2012-04-18
最終更新日2012-05-02
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains.
Proc.Natl.Acad.Sci.USA, 109, 2012
3ZXK
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BU of 3zxk by Molmil
Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIAXHD3, alpha-L-arabinofuranose-(1-2)-[beta-D-xylopyranose-(1-4)]beta-D-xylopyranose-(1-4)-beta-D-xylopyranose
著者McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J.
登録日2011-08-11
公開日2012-04-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains.
Proc.Natl.Acad.Sci.USA, 109, 2012
6D08
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BU of 6d08 by Molmil
Crystal structure of an engineered bump-hole complex of mutant human chromobox homolog 1 (CBX1) with H3K9bn peptide
分子名称: Chromobox protein homolog 1, GLYCEROL, Histone H3.1, ...
著者Arora, S, Horne, W.S, Islam, K.
登録日2018-04-10
公開日2019-04-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Engineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions.
J.Am.Chem.Soc., 141, 2019
3ZXL
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BU of 3zxl by Molmil
Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HIAXHD3
著者McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J.
登録日2011-08-11
公開日2012-04-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.871 Å)
主引用文献Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains.
Proc.Natl.Acad.Sci.USA, 109, 2012
6CU8
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BU of 6cu8 by Molmil
Alpha Synuclein fibril formed by full length protein - Twister Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
6AOZ
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BU of 6aoz by Molmil
Crystal structure of human FLASH N-terminal domain C54S/C83A (Crystal form 1)
分子名称: 1,2-ETHANEDIOL, CASP8-associated protein 2
著者Aik, W.S, Tong, L.
登録日2017-08-16
公開日2017-11-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing.
PLoS ONE, 12, 2017
2AG3
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BU of 2ag3 by Molmil
Heterocyclic Peptide Backbone Modification in Gcn4-pLI Based Coiled Coils: Substitution of the K(15)-L(16) amide with a triazole
分子名称: GCN4-pLI
著者Horne, W.S, Ghadiri, M.R.
登録日2005-07-26
公開日2006-08-08
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Copper-Catalyzed Azide-Alkyne Cycloaddition as a Non-native Ligation Strategy toward Backbone-Modified Peptides
To be Published
8T0H
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BU of 8t0h by Molmil
Backbone Dialkylation in Peptide Hairpins: (S)-Ethylpropylglycine variant
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Horne, W.S, Lengyel, G.A.
登録日2023-06-01
公開日2023-08-16
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
8T0I
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BU of 8t0i by Molmil
Backbone Dialkylation in Peptide Hairpins: (R)-Ethylpropylglycine variant
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Horne, W.S, Lengyel, G.A.
登録日2023-06-01
公開日2023-08-16
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
8T0G
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BU of 8t0g by Molmil
Backbone Dialkylation in Peptide Hairpins: Natural Backbone Prototype
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Horne, W.S, Lengyel, G.A.
登録日2023-06-01
公開日2023-08-16
実験手法SOLUTION NMR
主引用文献Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
6BTI
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BU of 6bti by Molmil
Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with N-arachidonoylethanolamine (AEA)
分子名称: (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide, DI(HYDROXYETHYL)ETHER, Retinol-binding protein 2
著者Silvaroli, J.A, Blaner, W.S, Lodowski, D.T, Golczak, M.
登録日2017-12-06
公開日2018-12-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight.
Sci Adv, 6, 2020
8UM7
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BU of 8um7 by Molmil
Site-specific Aspartic Acid Dehydration and Isomerization in Streptococcal Protein GB1: Wild-type Protein
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Guseman, A.J, Gronenborn, A.M, Horne, W.S.
登録日2023-10-17
公開日2024-05-01
実験手法SOLUTION NMR
主引用文献Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis.
Protein Sci., 33, 2024
8UM9
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BU of 8um9 by Molmil
Site-specific Aspartic Acid Dehydration and Isomerization in Streptococcal Protein GB1: D-Asp40 Variant
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Guseman, A.J, Gronenborn, A.M, Horne, W.S.
登録日2023-10-17
公開日2024-05-01
実験手法SOLUTION NMR
主引用文献Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis.
Protein Sci., 33, 2024
8UMA
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BU of 8uma by Molmil
Site-specific Aspartic Acid Dehydration and Isomerization in Streptococcal Protein GB1: D-isoAsp40 Variant
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Guseman, A.J, Gronenborn, A.M, Horne, W.S.
登録日2023-10-17
公開日2024-05-01
実験手法SOLUTION NMR
主引用文献Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis.
Protein Sci., 33, 2024
8UMS
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BU of 8ums by Molmil
Site-specific Aspartic Acid Dehydration and Isomerization in Streptococcal Protein GB1: L-isoAsp40 Variant
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Guseman, A.J, Gronenborn, A.M, Horne, W.S.
登録日2023-10-18
公開日2024-05-01
実験手法SOLUTION NMR
主引用文献Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis.
Protein Sci., 33, 2024
8UMB
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BU of 8umb by Molmil
Site-specific Aspartic Acid Dehydration and Isomerization in Streptococcal Protein GB1: L-Aspartyl Succinimide 40-41 Variant
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Guseman, A.J, Gronenborn, A.M, Horne, W.S.
登録日2023-10-17
公開日2024-05-01
実験手法SOLUTION NMR
主引用文献Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis.
Protein Sci., 33, 2024
2AHP
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BU of 2ahp by Molmil
GCN4 leucine zipper, mutation of Lys15 to epsilon-azido-Lys
分子名称: General control protein GCN4
著者Horne, W.S, Ghadiri, M.R.
登録日2005-07-28
公開日2006-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献GCN4 leucine zipper, mutation of Lys15 to epsilon-azido-Lys
To be Published

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件を2024-06-12に公開中

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