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Human ABCA4 structure in the unbound state
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ...
著者	Scortecci, J.F, Van Petegem, F, Molday, R.S.
登録日	2021-03-14
公開日	2021-09-08
最終更新日	2021-10-20
実験手法	ELECTRON MICROSCOPY (3.6 Å)
主引用文献	Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease. Nat Commun, 12, 2021

7KR6

Glycoside hydrolase family 16 endo-glucanase from Bacteroides ovatus in complex with G4G3G-2F-DNP
分子名称:	Glycoside hydrolase family 16 protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-2-deoxy-2-fluoro-alpha-D-glucopyranose
著者	Tamura, K, Brumer, H, van Petegem, F.
登録日	2020-11-18
公開日	2021-05-19
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (1.56 Å)
主引用文献	Orthogonal Active-Site Labels for Mixed-Linkage endo-beta-Glucanases. Acs Chem.Biol., 16, 2021

6B27

Crystal structure of human STAC2 Tandem SH3 Domains (296-411) in complex with a CaV1.1 II-III loop peptide
分子名称:	CHLORIDE ION, SH3 and cysteine-rich domain-containing protein 2, SULFATE ION, ...
著者	Wong King Yuen, S.M, Van Petegem, F.
登録日	2017-09-19
公開日	2017-10-25
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (1.73 Å)
主引用文献	Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

6B28

Crystal structure of human STAC2 Tandem SH3 Domains Q347I (296-411)
分子名称:	SH3 and cysteine-rich domain-containing protein 2
著者	Wong King Yuen, S.M, Tung, C.C, Van Petegem, F.
登録日	2017-09-19
公開日	2017-10-25
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

6B26

Crystal structure of human STAC2 Tandem SH3 Domains (296-411)
分子名称:	SH3 and cysteine-rich domain-containing protein 2
著者	Wong King Yuen, S.M, Van Petegem, F.
登録日	2017-09-19
公開日	2017-10-25
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.2 Å)
主引用文献	Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

6B25

Crystal structure of human STAC1 Tandem SH3 Domains (288-402)
分子名称:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SH3 and cysteine-rich domain-containing protein
著者	Wong King Yuen, S.M, Van Petegem, F.
登録日	2017-09-19
公開日	2017-10-25
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.39 Å)
主引用文献	Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

6B29

Crystal structure of the second SH3 domain of STAC3 (309-364)
分子名称:	SH3 and cysteine-rich domain-containing protein 3
著者	Wong King Yuen, S.M, Van Petegem, F.
登録日	2017-09-19
公開日	2017-10-25
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (1.3 Å)
主引用文献	Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

6DAF

2.4 Angstrom crystal structure of the F141L Ca/CaM:CaV1.2 IQ domain complex
分子名称:	CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者	Wang, K, Van Petegem, F.
登録日	2018-05-01
公開日	2018-10-17
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

6DAE

2.0 Angstrom crystal structure of the D95V Ca/CaM:CaV1.2 IQ domain complex
分子名称:	CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者	Wang, K, Lu, J, Van Petegem, F.
登録日	2018-05-01
公開日	2018-10-17
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

6DAD

1.65 Angstrom crystal structure of the N97I Ca/CaM:CaV1.2 IQ domain complex
分子名称:	CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者	Wang, K, Van Petegem, F.
登録日	2018-05-01
公開日	2018-10-17
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

6DAH

2.5 Angstrom crystal structure of the N97S CaM mutant
分子名称:	CALCIUM ION, Calmodulin-1
著者	Wang, K, Van Petegem, F.
登録日	2018-05-01
公開日	2018-10-17
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.502 Å)
主引用文献	Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

5SV8

Crystal Structure of the catalytic nucleophile and surface cysteine mutant of VvEG16 in complex with a xyloglucan oligosaccharide
分子名称:	alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, probable xyloglucan endotransglucosylase/hydrolase protein 19
著者	McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H.
登録日	2016-08-05
公開日	2016-09-21
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.588 Å)
主引用文献	Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases. Plant J., 89, 2017

5VSN

Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080-1253) disease mutant P1124L
分子名称:	GLYCEROL, POTASSIUM ION, Ryanodine receptor 2
著者	Yuchi, Z, Van Petegem, F.
登録日	2017-05-12
公開日	2018-05-23
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.439 Å)
主引用文献	Cardiac hypertrophy and arrhythmia in mice induced by a mutation in ryanodine receptor 2. JCI Insight, 5, 2019

3QR5

Structure of the first domain of a cardiac Ryanodine Receptor mutant with exon 3 deleted
分子名称:	Cardiac Ca2+ release channel
著者	Lobo, P.A, Van Petegem, F.
登録日	2011-02-17
公開日	2011-06-08
最終更新日	2023-07-26
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	The deletion of exon 3 in the cardiac ryanodine receptor is rescued by beta strand switching. Structure, 19, 2011

4MZ2

Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain
分子名称:	Sodium channel subunit beta-4
著者	Das, S, Van Petegem, F.
登録日	2013-09-28
公開日	2013-12-04
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.722 Å)
主引用文献	Crystallographic insights into sodium-channel modulation by the beta 4 subunit. Proc.Natl.Acad.Sci.USA, 110, 2013

4MZ3

Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W mutant
分子名称:	Sodium channel subunit beta-4
著者	Das, S, Van Petegem, F.
登録日	2013-09-28
公開日	2013-12-04
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.741 Å)
主引用文献	Crystallographic insights into sodium-channel modulation by the beta 4 subunit. Proc.Natl.Acad.Sci.USA, 110, 2013

3ILA

Crystal structure of rabbit ryanodine receptor 1 N-terminal domain (9-205)
分子名称:	Ryanodine receptor 1
著者	Lobo, P.A, Van Petegem, F.
登録日	2009-08-06
公開日	2009-11-17
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations. Structure, 17, 2009

4P9I

Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253)
分子名称:	Ryanodine receptor 2
著者	Lau, K, Van Petegem, F.
登録日	2014-04-04
公開日	2014-11-05
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (1.3401 Å)
主引用文献	Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain. Nat Commun, 5, 2014

3DVE

Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain complex
分子名称:	CALCIUM ION, Calmodulin, NICKEL (II) ION, ...
著者	Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日	2008-07-18
公開日	2008-11-04
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.35 Å)
主引用文献	Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation. Structure, 16, 2008

3DVM

Crystal Structure of Ca2+/CaM-CaV2.1 IQ domain complex
分子名称:	CALCIUM ION, Calmodulin, Voltage-dependent P/Q-type calcium channel subunit alpha-1A
著者	Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日	2008-07-18
公開日	2008-11-04
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation. Structure, 16, 2008

3DVK

Crystal Structure of Ca2+/CaM-CaV2.3 IQ domain complex
分子名称:	CALCIUM ION, Calmodulin, Voltage-dependent R-type calcium channel subunit alpha-1E
著者	Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日	2008-07-18
公開日	2008-11-04
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation. Structure, 16, 2008

3FYQ

Structure of Drosophila melanogaster talin IBS2 domain (residues 1981-2168)
分子名称:	CG6831-PA (Talin)
著者	Cheung, T.Y.S, Fairchild, M.J, Zarivach, R, Tanentzapf, G, Van Petegem, F.
登録日	2009-01-22
公開日	2009-02-03
最終更新日	2018-01-24
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Crystal structure of the talin integrin binding domain 2. J.Mol.Biol., 387, 2009

3DVJ

Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain (without cloning artifact, HM to TV) complex
分子名称:	CALCIUM ION, Calmodulin, Voltage-dependent N-type calcium channel subunit alpha-1B
著者	Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日	2008-07-18
公開日	2008-11-04
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation. Structure, 16, 2008

4I8M

Crystal structure of rabbit Ryanodine receptor 1 (residues 1-536) disease mutant V219I
分子名称:	GLYCEROL, Ryanodine receptor 1
著者	Kimlicka, L, Van Petegem, F.
登録日	2012-12-03
公開日	2013-02-20
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface. Nat Commun, 4, 2013

4I1E

Crystal structure of Rabbit Ryanodine Receptor 1 (residues 1-536) disease mutant G249R
分子名称:	Ryanodine receptor 1
著者	Kimlicka, L, Van Petegem, F.
登録日	2012-11-20
公開日	2013-02-20
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface. Nat Commun, 4, 2013

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