6A68
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a68 by Molmil](/molmil-images/mine/6a68) | the crystal structure of rat calcium-dependent activator protein for secretion (CAPS) DAMH domain | 分子名称: | Calcium-dependent secretion activator 1, POTASSIUM ION | 著者 | Zhou, H, Wei, Z.Q, Yao, D.Q, Zhang, R.G, Ma, C. | 登録日 | 2018-06-26 | 公開日 | 2019-03-13 | 最終更新日 | 2019-11-20 | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | 主引用文献 | Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis. Cell Rep, 26, 2019
|
|
6A30
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a30 by Molmil](/molmil-images/mine/6a30) | Crystal Structure of Munc13-1 MUN Domain and Synaptobrevin-2 Juxtamembrane Linker Region | 分子名称: | Protein unc-13 homolog A, Synaptobrevin-2 juxtamembrane linker peptide | 著者 | Wang, S, Li, Y, Gong, J.H, Ye, S, Yang, X.F, Zhang, R.G, Ma, C. | 登録日 | 2018-06-14 | 公開日 | 2019-01-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.793 Å) | 主引用文献 | Munc18 and Munc13 serve as a functional template to orchestrate neuronal SNARE complex assembly. Nat Commun, 10, 2019
|
|
3SI8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3si8 by Molmil](/molmil-images/mine/3si8) | Human DNA polymerase eta - DNA ternary complex with the 5'T of a CPD in the active site (TT2) | 分子名称: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, ... | 著者 | Biertumpfel, C, Zhao, Y, Kondo, Y, Ramon-Maiques, S, Gregory, M, Lee, J.Y, Masutani, C, Lehmann, A.R, Hanaoka, F, Yang, W. | 登録日 | 2011-06-17 | 公開日 | 2011-08-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
|
|
5GSQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gsq by Molmil](/molmil-images/mine/5gsq) | Crystal structure of IgG Fc with a homogeneous glycoform and Antibody-Dependent Cellular Cytotoxicity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, C.-L, Hsu, J.-C, Lin, C.-W, Wu, C.-Y, Wong, C.-H, Ma, C. | 登録日 | 2016-08-17 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of a Homogeneous IgG-Fc Glycoform with the N-Glycan Designed to Maximize the Antibody Dependent Cellular Cytotoxicity ACS Chem. Biol., 12, 2017
|
|
7WG3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wg3 by Molmil](/molmil-images/mine/7wg3) | Structural basis of interleukin-17B receptor in complex with a neutralizing antibody D9 for guiding humanization and affinity maturation for cancer therapy | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D9 Fab, IL17RB protein, ... | 著者 | Lee, W.H, Chen, X.R, Liu, I.J, Lee, J.H, Hu, C.M, Wu, H.C, Wang, S.K, Lee, W.H, Ma, C. | 登録日 | 2021-12-28 | 公開日 | 2022-11-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation. Cell Rep, 41, 2022
|
|
7VS3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vs3 by Molmil](/molmil-images/mine/7vs3) | The crystal structure of rat calcium-dependent activator protein for secretion (CAPS) C2PH | 分子名称: | Calcium-dependent secretion activator 1, SULFATE ION | 著者 | Zhou, H, Wei, Z.Q, Zhang, L, Ren, Y.J, Ma, C. | 登録日 | 2021-10-25 | 公開日 | 2023-02-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | 主引用文献 | The C 2 and PH domains of CAPS constitute an effective PI(4,5)P2-binding unit essential for Ca 2+ -regulated exocytosis. Structure, 31, 2023
|
|
5E4E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e4e by Molmil](/molmil-images/mine/5e4e) | Engineered Interleukin-13 bound to receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13, Interleukin-13 receptor subunit alpha-1, ... | 著者 | Moraga, I, Thomas, C, Jude, K.M, Garcia, K.C. | 登録日 | 2015-10-05 | 公開日 | 2015-12-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency. Sci.Signal., 8, 2015
|
|
4QFT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qft by Molmil](/molmil-images/mine/4qft) | |
2XA8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xa8 by Molmil](/molmil-images/mine/2xa8) | Crystal structure of the Fab domain of omalizumab at 2.41A | 分子名称: | OMALIZUMAB HEAVY CHAIN, OMALIZUMAB LIGHT CHAIN | 著者 | Huang, C.H, Hung, F.H.A, Lim, C, Chang, T.W, Ma, C. | 登録日 | 2010-03-30 | 公開日 | 2011-05-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structural and Physical Basis for Anti-IgE Therapy. Sci Rep, 5, 2015
|
|
7VQ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vq1 by Molmil](/molmil-images/mine/7vq1) | Structure of Apo-hsTRPM2 channel | 分子名称: | Transient receptor potential cation channel subfamily M member 2 | 著者 | Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W. | 登録日 | 2021-10-18 | 公開日 | 2021-12-22 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel. Cell Rep, 37, 2021
|
|
7VQ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vq2 by Molmil](/molmil-images/mine/7vq2) | Structure of Apo-hsTRPM2 channel TM domain | 分子名称: | Transient receptor potential cation channel subfamily M member 2 | 著者 | Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W. | 登録日 | 2021-10-18 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel. Cell Rep, 37, 2021
|
|
1R3B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1r3b by Molmil](/molmil-images/mine/1r3b) | Solution structure of xenopus laevis Mob1 | 分子名称: | MOB1 | 著者 | Ponchon, L, Dumas, C, Kajava, A.V, Fesquet, D, Padilla, A. | 登録日 | 2003-10-01 | 公開日 | 2004-09-28 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of Mob1, a mitotic exit network protein and its interaction with an NDR kinase peptide J.Mol.Biol., 337, 2004
|
|
1T7H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t7h by Molmil](/molmil-images/mine/1t7h) | X-ray structure of [Lys(-2)-Arg(-1)-des(17-21)]-endothelin-1 peptide | 分子名称: | Endothelin-1 | 著者 | Hoh, F, Cerdan, R, Kaas, Q, Nishi, Y, Chiche, L, Kubo, S, Chino, N, Kobayashi, Y, Dumas, C, Aumelas, A. | 登録日 | 2004-05-10 | 公開日 | 2004-12-21 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | High-resolution X-ray structure of the unexpectedly stable dimer of the [Lys(-2)-Arg(-1)-des(17-21)]endothelin-1 peptide Biochemistry, 43, 2004
|
|
1TUK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tuk by Molmil](/molmil-images/mine/1tuk) | Crystal structure of liganded type 2 non specific lipid transfer protein from wheat | 分子名称: | 1-MYRISTOYL-2-HYDROXY-SN-GLYCERO-3-[PHOSPHO-RAC-(1-GLYCEROL)], IODIDE ION, Nonspecific lipid-transfer protein 2G | 著者 | Hoh, F, Pons, J.L, Gautier, M.F, De Lamotte, F, Dumas, C. | 登録日 | 2004-06-25 | 公開日 | 2005-04-05 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Structure of a liganded type 2 non-specific lipid-transfer protein from wheat and the molecular basis of lipid binding. Acta Crystallogr.,Sect.D, 61, 2005
|
|
1ZXO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zxo by Molmil](/molmil-images/mine/1zxo) | X-ray Crystal Structure of Protein Q8A1P1 from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium Target BtR25. | 分子名称: | conserved hypothetical protein Q8A1P1 | 著者 | Kuzin, A.P, Yong, W, Forouhar, F, Vorobiev, S, Xiao, R, Ma, C, Acton, T, Montelione, G.T, Hunt, J, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2005-06-08 | 公開日 | 2005-07-05 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | X-Ray structure of the hypothetical protein Q8A1P1 at the resolution 3.2A. Northeast Structural Genomics Consortium target BtR25. To be Published
|
|
3S83
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s83 by Molmil](/molmil-images/mine/3s83) | EAL domain of phosphodiesterase PdeA | 分子名称: | GGDEF family protein, POTASSIUM ION | 著者 | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Massa, C, Schirmer, T, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2011-05-27 | 公開日 | 2011-06-29 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Crystal structure of EAL domain from Caulobacter crescentus CB15 To be Published
|
|
1T6F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t6f by Molmil](/molmil-images/mine/1t6f) | Crystal Structure of the Coiled-coil Dimerization Motif of Geminin | 分子名称: | Geminin | 著者 | Thepaut, M, Maiorano, D, Guichou, J.-F, Auge, M.-T, Dumas, C, Mechali, M, Padilla, A. | 登録日 | 2004-05-06 | 公開日 | 2004-07-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Crystal Structure of the Coiled-coil Dimerization Motif of Geminin: Structural and Functional Insights on DNA Replication Regulation J.Mol.Biol., 342, 2004
|
|
3U2E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u2e by Molmil](/molmil-images/mine/3u2e) | EAL domain of phosphodiesterase PdeA in complex with 5'-pGpG and Mg++ | 分子名称: | GGDEF family protein, MAGNESIUM ION, RNA (5'-R(P*GP*G)-3') | 著者 | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Massa, C, Schirmer, T, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2011-10-03 | 公開日 | 2011-10-12 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | EAL domain from Caulobacter crescentus in complex with 5'-pGpG and Mg++ To be Published
|
|
3GR4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gr4 by Molmil](/molmil-images/mine/3gr4) | Activator-Bound Structure of Human Pyruvate Kinase M2 | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2009-03-24 | 公開日 | 2009-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Activator-Bound Structures of Human Pyruvate Kinase M2 to be published
|
|
3GQY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gqy by Molmil](/molmil-images/mine/3gqy) | Activator-Bound Structure of Human Pyruvate Kinase M2 | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine, L(+)-TARTARIC ACID, ... | 著者 | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2009-03-24 | 公開日 | 2009-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Activator-Bound Structures of Human Pyruvate Kinase M2 to be published
|
|
3F6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f6n by Molmil](/molmil-images/mine/3f6n) | |
4NPN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4npn by Molmil](/molmil-images/mine/4npn) | Crystal structure of human tetra-SUMO-2 | 分子名称: | Small ubiquitin-related modifier 2 | 著者 | Kung, C.C.-H, Naik, M.T, Chen, C.L, Ma, C, Huang, T.H. | 登録日 | 2013-11-22 | 公開日 | 2014-10-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.633 Å) | 主引用文献 | Structural analysis of poly-SUMO chain recognition by the RNF4-SIMs domain. Biochem.J., 462, 2014
|
|
4D8D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4d8d by Molmil](/molmil-images/mine/4d8d) | |
3BRW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3brw by Molmil](/molmil-images/mine/3brw) | Structure of the Rap-RapGAP complex | 分子名称: | BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Scrima, A, Thomas, C, Deaconescu, D, Wittinghofer, A. | 登録日 | 2007-12-21 | 公開日 | 2008-03-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues Embo J., 27, 2008
|
|
3FWL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fwl by Molmil](/molmil-images/mine/3fwl) | Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli | 分子名称: | MOENOMYCIN, Penicillin-binding protein 1B | 著者 | Sung, M.T, Lai, Y.T, Huang, C.Y, Chou, L.Y, Wong, C.H, Ma, C. | 登録日 | 2009-01-19 | 公開日 | 2009-06-02 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (3.086 Å) | 主引用文献 | Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|