1T7H
X-ray structure of [Lys(-2)-Arg(-1)-des(17-21)]-endothelin-1 peptide
Summary for 1T7H
Entry DOI | 10.2210/pdb1t7h/pdb |
Descriptor | Endothelin-1 (2 entities in total) |
Functional Keywords | endothelin, dimer, salt bridge, cysteine stabilized helical motif, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P05305 |
Total number of polymer chains | 2 |
Total formula weight | 4287.11 |
Authors | Hoh, F.,Cerdan, R.,Kaas, Q.,Nishi, Y.,Chiche, L.,Kubo, S.,Chino, N.,Kobayashi, Y.,Dumas, C.,Aumelas, A. (deposition date: 2004-05-10, release date: 2004-12-21, Last modification date: 2017-10-11) |
Primary citation | Hoh, F.,Cerdan, R.,Kaas, Q.,Nishi, Y.,Chiche, L.,Kubo, S.,Chino, N.,Kobayashi, Y.,Dumas, C.,Aumelas, A. High-resolution X-ray structure of the unexpectedly stable dimer of the [Lys(-2)-Arg(-1)-des(17-21)]endothelin-1 peptide Biochemistry, 43:15154-15168, 2004 Cited by PubMed: 15568807DOI: 10.1021/bi049098a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.13 Å) |
Structure validation
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