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8CKL
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BU of 8ckl by Molmil
Semaphorin-5A TSR 3-4 domains in complex with sucrose octasulfate (SOS)
分子名称: 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose-(1-2)-1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose, Semaphorin-5A, alpha-D-mannopyranose
著者Nagy, G.N, Duman, R, Harlos, K, El Omari, K, Wagner, A, Jones, E.Y.
登録日2023-02-15
公開日2024-02-28
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Semaphorin-5A TSR 3-4 domains in complex with sucrose octasulfate (SOS)
To Be Published
5BQ8
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Crystal structure of Norrin, a Wnt signalling activator, Crystal Form II
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Norrin
著者Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
登録日2015-05-28
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BPB
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BU of 5bpb by Molmil
Crystal structure of the cysteine-rich domain of human Frizzled 4 - Crystal Form I
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4
著者Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
登録日2015-05-27
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BPQ
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BU of 5bpq by Molmil
Crystal structure of the cysteine-rich domain of human Frizzled 4 - Crystal Form II
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Frizzled-4
著者Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
登録日2015-05-28
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BQC
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Crystal structure of Norrin in complex with the cysteine-rich domain of Frizzled 4 and sucrose octasulfate
分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, ...
著者Chang, T.-H, Hsieh, F.-L, Zebisch, M, Harlos, K, Jones, E.Y.
登録日2015-05-28
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
3GJF
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BU of 3gjf by Molmil
Rational development of high-affinity T-cell receptor-like antibodies
分子名称: Antibody heavy chain, Antibody light chain, Beta-2-microglobulin, ...
著者Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E, Kleber, S, Stenner-Liewen, F, Bauer, S, McMichael, A, Knuth, A, Abken, H, Hombach, A.A, Cerundolo, V, Jones, E.Y, Renner, C.
登録日2009-03-08
公開日2009-04-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
3GIV
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BU of 3giv by Molmil
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
分子名称: Beta-2-microglobulin, HIV-1 peptide, HLA class I histocompatibility antigen, ...
著者Stewart-Jones, G, Iversen, A.K.N, Jones, E.Y.
登録日2009-03-06
公開日2009-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Nat.Immunol., 10, 2009
3GJE
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BU of 3gje by Molmil
Rational development of high-affinity T-cell receptor-like antibodies
分子名称: Fab Heavy Chain, Fab Light Chain
著者Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E, Kleber, S, Stenner-Liewen, F, Bauer, S, McMichael, A, Knuth, A, Abken, H, Hombach, A.A, Cerundolo, V, Jones, E.Y, Renner, C.
登録日2009-03-08
公開日2009-04-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
2YPK
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BU of 2ypk by Molmil
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms
分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, ...
著者Stewart-Jones, G.B, Simpson, P, Van Der Merwe, P.A, Easterbrook, P, Mcmichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M.
登録日2012-10-30
公開日2012-11-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
6FKM
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BU of 6fkm by Molmil
Drosophila Plexin A in complex with Semaphorin 1b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MIP07328p, Plexin A, ...
著者Rozbesky, D, Harlos, K, Jones, E.Y.
登録日2018-01-24
公開日2019-02-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Structural basis of semaphorin-plexin cis interaction.
Embo J., 2020
6FKK
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BU of 6fkk by Molmil
Drosophila Semaphorin 1b, extracellular domains 1-2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MIP07328p, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rozbesky, D, Harlos, K, Jones, E.Y.
登録日2018-01-24
公開日2019-02-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning.
Nat Commun, 10, 2019
6FKN
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Drosophila Plexin A in complex with Semaphorin 1b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MIP07328p, Plexin A, ...
著者Rozbesky, D, Harlos, K, Jones, E.Y.
登録日2018-01-24
公開日2019-02-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (4.801 Å)
主引用文献Structural basis of semaphorin-plexin cis interaction.
Embo J., 2020
2YPL
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BU of 2ypl by Molmil
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms
分子名称: AGA T-CELL RECEPTOR ALPHA CHAIN, AGA T-CELL RECEPTOR BETA CHAIN, BETA-2-MICROGLOBULIN, ...
著者Stewart-Jones, G.B, Simpson, P, van der Merwe, P.A, Easterbrook, P, McMichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M.
登録日2012-10-30
公開日2012-11-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
6GBI
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BU of 6gbi by Molmil
Wnt signalling
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ly6/PLAUR domain-containing protein 6, ...
著者Zhao, Y, Jones, E.Y.
登録日2018-04-14
公開日2018-08-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structure of the Wnt signaling enhancer LYPD6 and its interactions with the Wnt coreceptor LRP6.
FEBS Lett., 592, 2018
6GGM
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BU of 6ggm by Molmil
HLA-E*01:03 in complex with the Mtb44 peptide variant: Mtb44*P2-Phe.
分子名称: Beta-2-microglobulin, MHC class I antigen, Mtb44*P2-Phe peptide variant (ARG-PHE-PRO-ALA-LYS-ALA-PRO-LEU-LEU), ...
著者Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K.
登録日2018-05-03
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.734 Å)
主引用文献Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GH4
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HLA-E*01:03 in complex with the Mtb44 peptide variant: Mtb44*P2-Gln.
分子名称: ARG-GLN-PRO-ALA-LYS-ALA-PRO-LEU-LEU, Beta-2-microglobulin, MHC class I antigen, ...
著者Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K.
登録日2018-05-04
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GH1
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BU of 6gh1 by Molmil
HLA-E*01:03 in complex with Mtb44
分子名称: Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], MHC class I antigen, ...
著者Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K.
登録日2018-05-04
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GHN
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BU of 6ghn by Molmil
HLA-E*01:03 in complex with the Mtb44 peptide variant: Mtb44*P9-Phe.
分子名称: ARG-LEU-PRO-ALA-LYS-ALA-PRO-LEU-PHE, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K.
登録日2018-05-08
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.542 Å)
主引用文献Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GL1
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HLA-E*01:03 in complex with the HIV epitope, RL9HIV
分子名称: ARG-MET-TYR-SER-PRO-THR-SER-ILE-LEU, Beta-2-microglobulin, MHC class I antigen, ...
著者Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K.
登録日2018-05-22
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.623 Å)
主引用文献Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
1B98
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NEUROTROPHIN 4 (HOMODIMER)
分子名称: CHLORIDE ION, PROTEIN (NEUROTROPHIN-4)
著者Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S.
登録日1999-02-22
公開日1999-02-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
6TR5
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BU of 6tr5 by Molmil
Melatonin-Notum complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, ...
著者Zhao, Y, Jones, E.Y.
登録日2019-12-17
公開日2020-01-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.509 Å)
主引用文献Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum.
J. Pineal Res., 68, 2020
6TR7
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N-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamide-Notum complex
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Palmitoleoyl-protein carboxylesterase NOTUM, ...
著者Zhao, Y, Jones, E.Y.
登録日2019-12-17
公開日2020-01-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum.
J. Pineal Res., 68, 2020
6TR6
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N-acetylserotonin-Notum complex
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ...
著者Zhao, Y, Jones, E.Y.
登録日2019-12-17
公開日2020-01-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum.
J. Pineal Res., 68, 2020
1B8M
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BU of 1b8m by Molmil
BRAIN DERIVED NEUROTROPHIC FACTOR, NEUROTROPHIN-4
分子名称: PROTEIN (BRAIN DERIVED NEUROTROPHIC FACTOR), PROTEIN (NEUROTROPHIN-4)
著者Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S.
登録日1999-02-01
公開日1999-02-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
1OGA
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BU of 1oga by Molmil
A structural basis for immunodominant human T-cell receptor recognition.
分子名称: BETA-2-MICROGLOBULIN, GILGFVFTL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Stewart-Jones, G.B.E, McMichael, A.J, Bell, J.I, Stuart, D.I, Jones, E.Y.
登録日2003-04-28
公開日2003-06-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A Structural Basis for Immunodominant Human T Cell Receptor Recognition
Nat.Immunol., 4, 2003

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件を2024-09-04に公開中

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