4G8R
 
 | | Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 | | 分子名称: | (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), Plasminogen activator inhibitor-1, SULFATE ION | | 著者 | Stuckey, J.A, Lawrence, D.A, Li, S.-H. | | 登録日 | 2012-07-23 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4G8O
 | | Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 | | 分子名称: | (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), 1,2-ETHANEDIOL, Plasminogen activator inhibitor 1, ... | | 著者 | Stuckey, J.A, Lawrence, D.A, Li, S.-H. | | 登録日 | 2012-07-23 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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5CDZ
 | | Crystal structure of conserpin in the latent state | | 分子名称: | Conserpin in the latent state, GLYCEROL | | 著者 | Porebski, B.T, McGowan, S, Keleher, S, Buckle, A.M. | | 登録日 | 2015-07-06 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.449 Å) | | 主引用文献 | Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
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5CE0
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5CDX
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6NMB
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6OKW
 | | Solution structure of VEK50 | | 分子名称: | Plasminogen-binding group A streptococcal M-like protein PAM | | 著者 | Yuan, Y, Castellino, F.J. | | 登録日 | 2019-04-15 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
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6OQK
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6OQJ
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6OKX
 | | Solution structure of VEK50RH1/AA | | 分子名称: | Plasminogen-binding group A streptococcal M-like protein PAM | | 著者 | Yuan, Y, Castellino, F.J. | | 登録日 | 2019-04-15 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
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6OQ9
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6OKY
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6U2J
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6U2W
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6U23
 | | EM structure of MPEG-1(w.t.) soluble pre-pore | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein | | 著者 | Pang, S.S, Bayly-Jones, C. | | 登録日 | 2019-08-19 | | 公開日 | 2019-09-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
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6U2L
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6U2K
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7THS
 | | Macrocyclic plasmin inhibitor | | 分子名称: | (2S)-butane-1,2-diol, (6S,9R,20R,23S)-N-{[4-(aminomethyl)phenyl]methyl}-20-[(benzenesulfonyl)amino]-3,13,21-trioxo-2,6,9,14,22-pentaazatetracyclo[23.2.2.2~6,9~.2~15,18~]tritriaconta-1(27),15,17,25,28,30-hexaene-23-carboxamide, Plasminogen, ... | | 著者 | Guojie, W. | | 登録日 | 2022-01-12 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors.
Chemmedchem, 18, 2023
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7UAH
 | | Macrocyclic plasmin inhibitor | | 分子名称: | (2~{R})-butane-1,2-diol, (6S,9R,19S,22R)-N-{[4-(aminomethyl)phenyl]methyl}-22-[(3-chlorobenzene-1-sulfonyl)amino]-3,12,21-trioxo-2,6,9,13,20-pentaazatetracyclo[22.2.2.2~6,9~.2~14,17~]dotriaconta-1(26),14,16,24,27,29-hexaene-19-carboxamide, Plasminogen, ... | | 著者 | Guojie, W. | | 登録日 | 2022-03-12 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors.
Chemmedchem, 18, 2023
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2GRV
 | | Crystal Structure of LpqW | | 分子名称: | LpqW | | 著者 | Marland, Z, Rossjohn, J. | | 登録日 | 2006-04-25 | | 公開日 | 2006-07-18 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Hijacking of a Substrate-binding Protein Scaffold for use in Mycobacterial Cell Wall Biosynthesis
J.Mol.Biol., 359, 2006
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6CXO
 | | Complement component-9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement component C9, ... | | 著者 | Law, R.H.P, Spicer, B.A, Caradoc-Davies, T.T. | | 登録日 | 2018-04-03 | | 公開日 | 2018-09-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
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6D3Z
 | | Protease SFTI complex | | 分子名称: | Plasminogen, Trypsin inhibitor 1 | | 著者 | Law, R.H.P, Wu, G. | | 登録日 | 2018-04-17 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma.
J. Med. Chem., 62, 2019
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6DLW
 | | Complement component polyC9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement component C9, beta-D-mannopyranose | | 著者 | Dunstone, M.A, Spicer, B.A, Law, R.H.P. | | 登録日 | 2018-06-03 | | 公開日 | 2018-09-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
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6D40
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6D3Y
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