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5FOG
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BU of 5fog by Molmil
Crystal structure of hte Cryptosporidium muris cytosolic leucyl-tRNA synthetase editing domain complex with a post-transfer editing analogue of norvaline (Nv2AA)
分子名称: 1,2-ETHANEDIOL, 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, LEUCYL-TRNA SYNTHETASE, ...
著者Palencia, A, Liu, R.J, Lukarska, M, Gut, J, Bougdour, A, Touquet, B, Wang, E.D, Alley, M.R.K, Rosenthal, P.J, Hakimi, M.A, Cusack, S.
登録日2015-11-20
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Cryptosporidium and Toxoplasma Parasites are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase.
Antimicrob.Agents Chemother., 60, 2016
5FOL
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BU of 5fol by Molmil
Crystal structure of the Cryptosporidium muris cytosolic leucyl-tRNA synthetase editing domain complex with a post-transfer editing analogue of isoeucine (Ile2AA)
分子名称: 2'-(L-ISOLEUCYL)AMINO-2'-DEOXYADENOSINE, LEUCYL-TRNA SYNTHETASE, PHOSPHATE ION
著者Palencia, A, Liu, R.J, Lukarska, M, Gut, J, Bougdour, A, Touquet, B, Wang, E.D, Alley, M.R.K, Rosenthal, P.J, Hakimi, M.A, Cusack, S.
登録日2015-11-24
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Cryptosporidium and Toxoplasma Parasites are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase.
Antimicrob.Agents Chemother., 60, 2016
5FON
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BU of 5fon by Molmil
Crystal structure of the Cryptosporidium muris cytosolic leucyl-tRNA synthetase editing domain (apo structure)
分子名称: LEUCYL-TRNA SYNTHETASE
著者Palencia, A, Liu, R.J, Lukarska, M, Gut, J, Bougdour, A, Touquet, B, Wang, E.D, Alley, M.R.K, Rosenthal, P.J, Hakimi, M.A, Cusack, S.
登録日2015-11-24
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cryptosporidium and Toxoplasma Parasites are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase.
Antimicrob.Agents Chemother., 60, 2016
8UZH
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BU of 8uzh by Molmil
SUMO fused Trehalose Synthase (TreS) of Mycobacterium tuberculosis
分子名称: CALCIUM ION, SUMO fused Trehalose Synthase (TreS),Trehalose synthase/amylase TreS
著者Pathirage, R, Ronning, D.R.
登録日2023-11-15
公開日2024-03-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Targeting Mycobacterium tuberculosis Persistence through Inhibition of the Trehalose Catalytic Shift.
Acs Infect Dis., 10, 2024
8UQV
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BU of 8uqv by Molmil
Trehalose Synthase (TreS) of Mycobacterium tuberculosis in complex with 6-TreAz compound
分子名称: 6-azido-6-deoxy-alpha-D-glucopyranose, CALCIUM ION, Trehalose synthase/amylase TreS, ...
著者Pathirage, R, Ronning, D.R.
登録日2023-10-24
公開日2024-03-27
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Targeting Mycobacterium tuberculosis Persistence through Inhibition of the Trehalose Catalytic Shift.
Acs Infect Dis., 10, 2024
6TPR
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BU of 6tpr by Molmil
PqsR (MvfR) bound to inhibitory compound 40
分子名称: 2-[(5-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]-~{N}-(4-pyridin-2-yloxyphenyl)ethanamide, Transcriptional regulator MvfR
著者Richardson, W.K, Emsley, J.
登録日2019-12-14
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm GrownPseudomonas aeruginosa.
Front Chem, 8, 2020
7D3Y
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BU of 7d3y by Molmil
Crystal structure of the osPHR2-osSPX2 complex
分子名称: INOSITOL HEXAKISPHOSPHATE, Protein PHOSPHATE STARVATION RESPONSE 2, SPX domain-containing protein 2,Isoform 1 of Core histone macro-H2A.1
著者Zhang, Q.X, Guan, Z.Y, Zuo, J.Q, Zhang, Z.F, Liu, Z.
登録日2020-09-21
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex.
Nat Commun, 13, 2022
7D3T
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BU of 7d3t by Molmil
Crystal structure of OSPHR2 in complex with DNA
分子名称: DNA (5'-D(P*CP*TP*CP*GP*GP*AP*TP*AP*TP*CP*CP*TP*CP*AP*AP*G)-3'), DNA (5'-D(P*GP*CP*TP*TP*GP*AP*GP*GP*AP*TP*AP*TP*CP*CP*GP*A)-3'), Protein PHOSPHATE STARVATION RESPONSE 2
著者Guan, Z.Y, Zhang, Z.F, Liu, Z.
登録日2020-09-20
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex.
Nat Commun, 13, 2022
6IR2
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BU of 6ir2 by Molmil
Crystal structure of red fluorescent protein mCherry complexed with the nanobody LaM2 at 1.4 Angstron resolution
分子名称: MCherry fluorescent protein, mCherry's nanobody LaM2
著者Ding, Y, Wang, Z.Y, Hu, R.T, Chen, X.
登録日2018-11-09
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.393 Å)
主引用文献Structural insights into the binding of nanobodies LaM2 and LaM4 to the red fluorescent protein mCherry.
Protein Sci., 30, 2021
6IR1
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BU of 6ir1 by Molmil
Crystal structure of red fluorescent protein mCherry complexed with the nanobody LaM4 at 1.9 Angstron resolution
分子名称: MCherry fluorescent protein, mCherry's nanobody LaM4
著者Ding, Y, Wang, Z.Y, Hu, R.T, Chen, X.
登録日2018-11-09
公開日2019-11-13
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.919 Å)
主引用文献Structural insights into the binding of nanobodies LaM2 and LaM4 to the red fluorescent protein mCherry.
Protein Sci., 30, 2021
5CI9
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BU of 5ci9 by Molmil
Crystal structure of human Tob in complex with inhibitor fragment 6
分子名称: 1-(propan-2-yl)-1H-benzimidazole-5-carboxylic acid, Protein Tob1, SODIUM ION
著者Bai, Y, Tashiro, S, Nagatoishi, S, Suzuki, T, Tsumoto, K, Bartlam, M, Yamamoto, T.
登録日2015-07-11
公開日2015-11-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach
Protein Cell, 6, 2015
7CVQ
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BU of 7cvq by Molmil
crystal structure of Arabidopsis CO CCT domain in complex with NF-YB2/YC3 and FT CORE1 DNA
分子名称: Chimera of Nuclear transcription factor Y subunit C-3 and Zinc finger protein CONSTANS, FT CORE1 DNA forward strand, FT CORE1 DNA reverse strand, ...
著者Lv, X, Du, J.
登録日2020-08-26
公開日2021-06-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural insights into the multivalent binding of the Arabidopsis FLOWERING LOCUS T promoter by the CO-NF-Y master transcription factor complex.
Plant Cell, 33, 2021
7CVO
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BU of 7cvo by Molmil
crystal structure of Arabidopsis CO CCT domain in complex with NF-YB3/YC4 and FT CORE2 DNA
分子名称: Chimera of Nuclear transcription factor Y subunit C-4 and Zinc finger protein CONSTANS, FT CORE2 DNA forward strand, FT CORE2 DNA reverse strand, ...
著者Lv, X, Du, J.
登録日2020-08-26
公開日2021-06-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into the multivalent binding of the Arabidopsis FLOWERING LOCUS T promoter by the CO-NF-Y master transcription factor complex.
Plant Cell, 33, 2021
5CI8
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BU of 5ci8 by Molmil
Crystal structure of human Tob in complex with inhibitor fragment 1
分子名称: Protein Tob1, pyrrolo[1,2-a]quinoxalin-4(5H)-one
著者Bai, Y, Tashiro, S, Nagatoishi, S, Suzuki, T, Tsumoto, K, Bartlam, M, Yamamoto, T.
登録日2015-07-11
公開日2015-11-18
最終更新日2015-12-09
実験手法X-RAY DIFFRACTION (2.328 Å)
主引用文献Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach
Protein Cell, 6, 2015
4ZHU
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BU of 4zhu by Molmil
Crystal structure of a bacterial repressor protein
分子名称: SULFATE ION, YfiR
著者Li, S, Li, T, Wang, Y, Bartlam, M.
登録日2015-04-27
公開日2016-04-27
実験手法X-RAY DIFFRACTION (2.3968 Å)
主引用文献Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1
Sci Rep, 5, 2015
4ZHW
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BU of 4zhw by Molmil
Crystal structure of a bacterial signalling protein (N-terminal truncation)
分子名称: YfiB
著者Li, S, Li, T, Wang, Y, Bartlam, M.
登録日2015-04-27
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.391 Å)
主引用文献Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1
Sci Rep, 5, 2015
4ZHY
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BU of 4zhy by Molmil
Crystal structure of a bacterial signalling complex
分子名称: FORMIC ACID, SULFATE ION, YfiB, ...
著者Li, S, Li, T, Wang, Y, Bartlam, M.
登録日2015-04-27
公開日2016-04-27
実験手法X-RAY DIFFRACTION (1.969 Å)
主引用文献Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1
Sci Rep, 5, 2015
4WY4
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BU of 4wy4 by Molmil
Crystal structure of autophagic SNARE complex
分子名称: Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8
著者Zhao, M, Brunger, A.T.
登録日2014-11-15
公開日2015-02-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.
Nature, 520, 2015
4Z3D
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BU of 4z3d by Molmil
Human carbonyl reductase 1 with glutathione in a protective configuration
分子名称: Carbonyl reductase [NADPH] 1, GLUTATHIONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Ding, Y, Liang, Q.
登録日2015-03-31
公開日2015-10-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights on the catalytic site protection of human carbonyl reductase 1 by glutathione.
J.Struct.Biol., 192, 2015
4ZHV
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BU of 4zhv by Molmil
Crystal structure of a bacterial signalling protein
分子名称: SULFATE ION, YfiB
著者Li, S, Li, T, Wang, Y, Bartlam, M.
登録日2015-04-27
公開日2016-04-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.585 Å)
主引用文献Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1
Sci Rep, 5, 2015
7X78
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BU of 7x78 by Molmil
L-fuculose 1-phosphate aldolase
分子名称: L-fuculose phosphate aldolase, MAGNESIUM ION, SULFATE ION
著者Lou, X, Zhang, Q, Bartlam, M.
登録日2022-03-09
公開日2022-04-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural characterization of an L-fuculose-1-phosphate aldolase from Klebsiella pneumoniae.
Biochem.Biophys.Res.Commun., 607, 2022
5DJU
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BU of 5dju by Molmil
Crystal structure of LOV2 (C450A) domain in complex with Zdk3
分子名称: CHLORIDE ION, Engineered protein, Zdk3 affibody, ...
著者Tarnawski, M, Wang, H, Yumerefendi, H, Hahn, K.M, Schlichting, I.
登録日2015-09-02
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献LOVTRAP: an optogenetic system for photoinduced protein dissociation.
Nat.Methods, 13, 2016
5DV2
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BU of 5dv2 by Molmil
Crystal structure of human CNOT6L in complex with cytidine-5'-monophosphate
分子名称: CCR4-NOT transcription complex subunit 6-like, CYTIDINE-5'-MONOPHOSPHATE
著者Zhang, Q, Bartlam, M.
登録日2015-09-21
公開日2016-05-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural basis for inhibition of the deadenylase activity of human CNOT6L
Febs Lett., 590, 2016
7YTJ
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BU of 7ytj by Molmil
Cryo-EM structure of VTC complex
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, INOSITOL HEXAKISPHOSPHATE, PHOSPHATE ION, ...
著者Guan, Z.Y, Chen, J, Liu, R.W, Chen, Y.K, Xing, Q, Du, Z.M, Liu, Z.
登録日2022-08-15
公開日2023-02-22
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex.
Nat Commun, 14, 2023
3F38
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BU of 3f38 by Molmil
Apoferritin: complex with 2,6-dimethylphenol
分子名称: 2,6-dimethylphenol, CADMIUM ION, Ferritin light chain, ...
著者Vedula, L.S, Economou, N.J, Rossi, M.J, Eckenhoff, R.G, Loll, P.J.
登録日2008-10-30
公開日2009-07-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A unitary anesthetic binding site at high resolution.
J.Biol.Chem., 284, 2009

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