7Q6C
 
 | | complement C6 FIM1-2 bound to CP010 antibody | | 分子名称: | ACETATE ION, CP010 heavy chain, CP010 light chain, ... | | 著者 | Olesen, H.G, Andersen, G.R. | | 登録日 | 2021-11-06 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.29274 Å) | | 主引用文献 | Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex.
J Innate Immun, 2022
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5O8W
 | | CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA | | 分子名称: | Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ... | | 著者 | Wirth, C, Andersen, G.R, Hunte, C. | | 登録日 | 2017-06-14 | | 公開日 | 2017-08-23 | | 最終更新日 | 2025-04-09 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A.
J. Biol. Chem., 292, 2017
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5NQW
 | | IgE-Fc in complex with single domain antibody 026 | | 分子名称: | 026, GLYCEROL, Immunoglobulin heavy constant epsilon, ... | | 著者 | Laursen, N.S, Jabs, F, Spillner, E, Andersen, G.R. | | 登録日 | 2017-04-21 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts Fc epsilon RI interaction.
Nat Commun, 9, 2018
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1NHY
 | | Crystal Structure of the GST-like Domain of Elongation Factor 1-gamma from Saccharomyces cerevisiae. | | 分子名称: | Elongation factor 1-gamma 1, SULFATE ION | | 著者 | Jeppesen, M.G, Ortiz, P, Kinzy, T.G, Andersen, G.R, Nyborg, J. | | 登録日 | 2002-12-20 | | 公開日 | 2003-01-14 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The Crystal Structure of the Glutathione S-Transferase-like Domain of Elongation Factor 1B{gamma} from Saccharomyces cerevisiae.
J.Biol.Chem., 278, 2003
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1PBU
 | | Solution structure of the C-terminal domain of the human eEF1Bgamma subunit | | 分子名称: | Elongation factor 1-gamma | | 著者 | Vanwetswinkel, S, Kriek, J, Andersen, G.R, Guntert, P, Dijk, J, Canters, G.W, Siegal, G. | | 登録日 | 2003-05-15 | | 公開日 | 2003-07-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 1H, (15)N and (13)C resonance assignments of the highly conserved 19 kDa C-terminal domain from human Elongation Factor 1Bgamma.
J.Biomol.Nmr, 26, 2003
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1PAQ
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1U2R
 | | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Jorgensen, R, Yates, S.P, Nilsson, J, Prentice, G.A, Teal, D.J, Merrill, A.R, Andersen, G.R. | | 登録日 | 2004-07-20 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
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6RU5
 | | human complement C3 in complex with the hC3Nb1 nanobody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Jensen, R.K, Andersen, G.R. | | 登録日 | 2019-05-27 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
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6RU3
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6RUS
 | | Structure of a functional properdin monomer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, SULFATE ION, ... | | 著者 | Pedersen, D.V, Andersen, G.R. | | 登録日 | 2019-05-29 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
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6RUV
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7ASG
 | | TGFBIp mutant R555W | | 分子名称: | Transforming growth factor-beta-induced protein ig-h3 | | 著者 | Nielsen, N.S, Gadeberg, T.A.F, Andersen, G.R. | | 登録日 | 2020-10-27 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy.
J.Biol.Chem., 297, 2021
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1ZM4
 | | Structure of the eEF2-ETA-bTAD complex | | 分子名称: | BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, Elongation factor 2, exotoxin A | | 著者 | Joergensen, R, Merrill, A.R, Yates, S.P, Marquez, V.E, Schwan, A.L, Boesen, T, Andersen, G.R. | | 登録日 | 2005-05-10 | | 公開日 | 2005-05-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.
Nature, 436, 2005
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1ZM2
 | | Structure of ADP-ribosylated eEF2 in complex with catalytic fragment of ETA | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Exotoxin A | | 著者 | Joergensen, R, Merrill, A.R, Yates, S.P, Marquez, V.E, Schwan, A.L, Boesen, T, Andersen, G.R. | | 登録日 | 2005-05-10 | | 公開日 | 2005-05-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.
Nature, 436, 2005
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1ZM3
 | | Structure of the apo eEF2-ETA complex | | 分子名称: | Elongation factor 2, exotoxin A | | 著者 | Joergensen, R, Merrill, A.R, Yates, S.P, Marquez, V.E, Schwan, A.L, Boesen, T, Andersen, G.R. | | 登録日 | 2005-05-10 | | 公開日 | 2005-05-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.
Nature, 436, 2005
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1ZM9
 | | Structure of eEF2-ETA in complex with PJ34 | | 分子名称: | Elongation factor 2, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, exotoxin A | | 著者 | Joergensen, R, Merrill, A.R, Yates, S.P, Marquez, V.E, Schwan, A.L, Boesen, T, Andersen, G.R. | | 登録日 | 2005-05-10 | | 公開日 | 2005-05-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.
Nature, 436, 2005
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8RD2
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6TAV
 | | Crystal structure of endopeptidase-induced alpha2-macroglobulin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... | | 著者 | Gomis-Ruth, F.X, Duquerroy, S, Trapani, S, Marrero, A, Goulas, T, Guevara, T, Andersen, G.A, Sottrup-Jensen, L, Navaza, J. | | 登録日 | 2019-10-30 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Cryo-EM structures shows the mechanistic basis of pan-peptidase inhibition by human alpha2-macroglobulin
Proc.Natl.Acad.Sci.USA, 2022
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7B29
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7B2A
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7B2D
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7B26
 | | CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3 | | 分子名称: | CirpA1, Properdin, alpha-D-mannopyranose, ... | | 著者 | Lea, S.M, Johnson, S, Braunger, K. | | 登録日 | 2020-11-26 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
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7B28
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8PIH
 | | Structure of Api m1 in complex with two nanobodies | | 分子名称: | CHLORIDE ION, Phospholipase A2, nanobdoy AM1-1, ... | | 著者 | Aagaard, J.B, Gandini, R, Spillner, E, Miehe, M, Andersen, G.R. | | 登録日 | 2023-06-21 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Nanobody-based IgG formats as blocking antibodies of the major honeybee venom allergen Api m 1
To be published
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