8RD2
Trypanosoma brucei Invariant Surface Glycoprotein 75 (ISG75)
Summary for 8RD2
| Entry DOI | 10.2210/pdb8rd2/pdb |
| Descriptor | Invariant surface glycoprotein (1 entity in total) |
| Functional Keywords | receptor, inhibitor, immunoglobulin, parasite, invariant, immunosuppressant |
| Biological source | Trypanosoma brucei |
| Total number of polymer chains | 2 |
| Total formula weight | 98441.90 |
| Authors | Stodkilde-Jorgensen, K.,Mikkelsen, J.H. (deposition date: 2023-12-07, release date: 2024-02-14, Last modification date: 2024-04-10) |
| Primary citation | Mikkelsen, J.H.,Stodkilde, K.,Jensen, M.P.,Hansen, A.G.,Wu, Q.,Lorentzen, J.,Graversen, J.H.,Andersen, G.R.,Fenton, R.A.,Etzerodt, A.,Thiel, S.,Andersen, C.B.F. Trypanosoma brucei Invariant Surface Glycoprotein 75 Is an Immunoglobulin Fc Receptor Inhibiting Complement Activation and Antibody-Mediated Cellular Phagocytosis. J Immunol., 212:1334-1344, 2024 Cited by PubMed: 38391367DOI: 10.4049/jimmunol.2300862 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.69 Å) |
Structure validation
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