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8HI4
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BU of 8hi4 by Molmil
Cryo-EM structure of the bi-functional malonyl-CoA reductase from Roseiflexus castenholzii
分子名称: Short-chain dehydrogenase/reductase SDR
著者Zhang, X, Xu, X, Xin, J.
登録日2022-11-18
公開日2023-05-31
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural basis of a bi-functional malonyl-CoA reductase (MCR) from the photosynthetic green non-sulfur bacterium Roseiflexus castenholzii.
Mbio, 14, 2023
8J1T
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BU of 8j1t by Molmil
Local refined cryo-EM structure of Omicron BA.5 RBD in complex with 8-9D Fab
分子名称: 8-9D heavy chain, 8-9D light chain, Spike protein
著者Xiang, Y, Li, R.
登録日2023-04-13
公開日2023-11-29
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A lung-selective delivery of mRNA encoding broadly neutralizing antibody against SARS-CoV-2 infection.
Nat Commun, 14, 2023
8HI6
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BU of 8hi6 by Molmil
Crystal structure of the NADP+ and MSA bound N terminal domain of bi-functional malonyl-CoA reductase from Roseiflexus castenholzii
分子名称: 3-oxidanylidenepropanoic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR
著者Zhang, X, Wu, W.P, Xu, X.
登録日2022-11-18
公開日2023-05-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of a bi-functional malonyl-CoA reductase (MCR) from the photosynthetic green non-sulfur bacterium Roseiflexus castenholzii.
Mbio, 14, 2023
1XML
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BU of 1xml by Molmil
Structure of human Dcps
分子名称: PHOSPHATE ION, heat shock-like protein 1
著者Chen, N, Song, H.
登録日2004-10-04
公開日2005-03-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping.
J.Mol.Biol., 347, 2005
5ZU6
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BU of 5zu6 by Molmil
A CBM32 derived from alginate lyase B (AlyB-OU02)
分子名称: CBM32 domain, SODIUM ION
著者Liu, W, Lyu, Q, Zhang, K.
登録日2018-05-07
公開日2018-06-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and biochemical characterization of a multidomain alginate lyase reveals a novel role of CBM32 in CAZymes
Biochim. Biophys. Acta, 1862, 2018
5ZU5
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BU of 5zu5 by Molmil
Crystal structure of a full length alginate lyase with CBM domain
分子名称: GLYCEROL, SODIUM ION, alginate lyase
著者Liu, W, Lyu, Q, Li, Z.
登録日2018-05-07
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and biochemical characterization of a multidomain alginate lyase reveals a novel role of CBM32 in CAZymes
Biochim. Biophys. Acta, 1862, 2018
6NQD
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BU of 6nqd by Molmil
Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer in complex with 8ANC195 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 heavy chain, ...
著者Fang, Q, Rossmann, M.G.
登録日2019-01-21
公開日2019-03-06
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献A sequestered fusion peptide in the structure of an HIV-1 transmitted founder envelope trimer.
Nat Commun, 10, 2019
1XMM
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BU of 1xmm by Molmil
Structure of human Dcps bound to m7GDP
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, N7-METHYL-GUANOSINE-5'-MONOPHOSPHATE, PHOSPHATE ION, ...
著者Chen, N, Song, H.
登録日2004-10-04
公開日2005-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping.
J.Mol.Biol., 347, 2005
3DBF
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BU of 3dbf by Molmil
Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 562
分子名称: 4-({1-[3-(3-amino-3-oxopropyl)-5-chlorophenyl]-3-methyl-1H-pyrazolo[4,3-c]pyridin-6-yl}amino)-3-methoxy-N-(1-methylpipe ridin-4-yl)benzamide, Polo-like kinase
著者Elling, R.A, Zhu, J, Barr, K.J, Romanowski, M.J.
登録日2008-05-31
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
7DMF
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BU of 7dmf by Molmil
A de novo protein that rigidly extends the structure of tVHS-like domain in tepsin with a new designed domain
分子名称: Designed protein EXTD-3
著者Xu, Y.
登録日2020-12-03
公開日2021-12-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献A backbone-centred energy function of neural networks for protein design.
Nature, 602, 2022
7E74
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BU of 7e74 by Molmil
Crystal structure of ENL YEATS domain T3 mutant in complex with histone H3 acetylation at K27
分子名称: ALA-ALA-ARG-ALY, Protein ENL
著者Li, Y, Li, H.
登録日2021-02-25
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022
7DCY
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BU of 7dcy by Molmil
Apo form of Mycoplasma genitalium RNase R
分子名称: MAGNESIUM ION, Ribonuclease R
著者Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X.
登録日2020-10-27
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.972 Å)
主引用文献Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
7DIC
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BU of 7dic by Molmil
Mycoplasma genitalium RNase R in complex with single-stranded RNA
分子名称: MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), Ribonuclease R
著者Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X.
登録日2020-11-18
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.242 Å)
主引用文献Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
7DOL
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BU of 7dol by Molmil
Mycoplasma genitalium RNase R in complex with double-stranded RNA
分子名称: MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), Ribonuclease R
著者Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X.
登録日2020-12-14
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
7DID
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BU of 7did by Molmil
Mycoplasma genitalium RNase R in complex with ribose methylated single-stranded RNA
分子名称: MAGNESIUM ION, RNA (5'-R(*AP*AP*AP*A)-3'), Ribonuclease R
著者Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X.
登録日2020-11-18
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
8JLW
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BU of 8jlw by Molmil
CCHFV envelope protein Gc in complex with Gc8
分子名称: Glycoprotein C,CCHFV envelope protein Gc fusion loops, Mouse antibody Gc8 heavy chain, Mouse antibody Gc8 light chain
著者Chong, T, Cao, S.
登録日2023-06-03
公開日2024-01-24
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.
Plos Pathog., 20, 2024
8JKD
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BU of 8jkd by Molmil
Cryo-EM structure of CCHFV envelope protein Gc trimer in complex with Gc13 Fab
分子名称: Glycoprotein C
著者Chong, T, Cao, S.
登録日2023-06-01
公開日2024-01-24
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.
Plos Pathog., 20, 2024
5GSA
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BU of 5gsa by Molmil
EED in complex with an allosteric PRC2 inhibitor
分子名称: Histone-lysine N-methyltransferase EZH2, N-(furan-2-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, Polycomb protein EED
著者Zhao, K, Zhao, M, Luo, X, Zhang, H.
登録日2016-08-15
公開日2017-02-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of
Nat. Chem. Biol., 13, 2017
7C00
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BU of 7c00 by Molmil
Crystal structure of the SRCR domain of human SCARA5.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Scavenger receptor class A member 5
著者Yu, B, He, Y.
登録日2020-04-29
公開日2020-09-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Interactions of ferritin with scavenger receptor class A members.
J.Biol.Chem., 295, 2020
2RHP
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BU of 2rhp by Molmil
The Thrombospondin-1 Polymorphism Asn700Ser Associated with Cornoary Artery Disease Causes Local and Long-Ranging Changes in Protein Structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Carlson, C.B, Keck, J.L, Mosher, D.F.
登録日2007-10-09
公開日2008-05-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Influences of the N700S Thrombospondin-1 Polymorphism on Protein Structure and Stability.
J.Biol.Chem., 283, 2008
2RR2
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BU of 2rr2 by Molmil
Structure of O-fucosylated epidermal growth factor-like repeat 12 of mouse Notch-1 receptor
分子名称: Neurogenic locus notch homolog protein 1, alpha-L-fucopyranose
著者Hosoguchi, K, Shimizu, K, Fujitani, N, Nishimura, S.
登録日2010-02-26
公開日2010-10-13
最終更新日2020-07-29
実験手法SOLUTION NMR
主引用文献Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
7BZZ
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BU of 7bzz by Molmil
Crystal structure of the SRCR domain of mouse SCARA5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Scavenger receptor class A member 5
著者Yu, B, He, Y.
登録日2020-04-29
公開日2020-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Interactions of ferritin with scavenger receptor class A members.
J.Biol.Chem., 295, 2020
2RR0
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BU of 2rr0 by Molmil
Structure of epidermal growth factor-like repeat 12 of mouse Notch-1 receptor
分子名称: Neurogenic locus notch homolog protein 1
著者Hosoguchi, K, Shimizu, K, Fujitani, N, Nishimura, S.
登録日2010-02-26
公開日2010-10-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
2RQZ
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BU of 2rqz by Molmil
Structure of sugar modified epidermal growth factor-like repeat 12 of mouse Notch-1 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, Neurogenic locus notch homolog protein 1
著者Shimizu, K, Fujitani, N, Hosoguchi, K, Nishimura, S.
登録日2010-02-26
公開日2010-10-13
最終更新日2020-07-29
実験手法SOLUTION NMR
主引用文献Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
2HIW
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BU of 2hiw by Molmil
Crystal Structure of Inactive Conformation Abl Kinase Catalytic Domain Complexed with Type II Inhibitor
分子名称: 7-AMINO-1-METHYL-3-(2-METHYL-5-{[3-(TRIFLUOROMETHYL)BENZOYL]AMINO}PHENYL)-2-OXO-2,3-DIHYDROPYRIMIDO[4,5-D]PYRIMIDIN-1-IUM, Proto-oncogene tyrosine-protein kinase ABL1
著者Lee, C.
登録日2006-06-29
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A general strategy for creating
Chem.Biol., 13, 2006

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