3L8H
| Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from B. bronchiseptica complexed with magnesium and phosphate | 分子名称: | FORMIC ACID, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Nguyen, H, Peisach, E, Allen, K.N. | 登録日 | 2009-12-31 | 公開日 | 2010-02-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) . Biochemistry, 49, 2010
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7E2Q
| Crystal structure of Mycoplasma pneumoniae Enolase | 分子名称: | Enolase, SULFATE ION | 著者 | Chen, R, Zhang, S, Gan, R, Wang, W, Ran, T, Xiong, Q, Shao, G, Feng, Z. | 登録日 | 2021-02-07 | 公開日 | 2022-02-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Evidence for the Rapid and Divergent Evolution of Mycoplasmas: Structural and Phylogenetic Analysis of Enolases. Front Mol Biosci, 8, 2022
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6M4J
| SspA in complex with cysteine | 分子名称: | CYSTEINE, PYRIDOXAL-5'-PHOSPHATE, SspA complex protein | 著者 | Liu, L, Gao, H. | 登録日 | 2020-03-07 | 公開日 | 2020-04-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Analysis of an l-Cysteine Desulfurase from an Ssp DNA Phosphorothioation System. Mbio, 11, 2020
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8HR2
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7E2P
| The Crystal Structure of Mycoplasma bovis enolase | 分子名称: | Enolase | 著者 | Chen, R, Zhang, S, Gan, R, Wang, W, Ran, T, Shao, G, Xiong, Q, Feng, Z. | 登録日 | 2021-02-07 | 公開日 | 2022-02-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Evidence for the Rapid and Divergent Evolution of Mycoplasmas: Structural and Phylogenetic Analysis of Enolases. Front Mol Biosci, 8, 2022
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8GYB
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8GYA
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8GY4
| Crystal structure of Alongshan virus methyltransferase | 分子名称: | Methyltransferase | 著者 | Chen, H, Lin, S, Lu, G.W. | 登録日 | 2022-09-21 | 公開日 | 2023-09-27 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses. Plos Pathog., 19, 2023
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8GY9
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8H5U
| Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-021 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb-021, ... | 著者 | Yang, J, Lin, S, Lu, G.W. | 登録日 | 2022-10-13 | 公開日 | 2023-10-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Development of a bispecific nanobody conjugate broadly neutralizes diverse SARS-CoV-2 variants and structural basis for its broad neutralization. Plos Pathog., 19, 2023
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8H5T
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6LPM
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3KA0
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3KC3
| MK2 complexed to inhibitor N4-(7-(benzofuran-2-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine | 分子名称: | MAP kinase-activated protein kinase 2, N~4~-[7-(1-benzofuran-2-yl)-1H-indazol-5-yl]pyrimidine-2,4-diamine | 著者 | Argiriadi, M.A, Talanian, R.V, Borhani, D.W. | 登録日 | 2009-10-20 | 公開日 | 2010-01-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | 2,4-Diaminopyrimidine MK2 inhibitors. Part I: Observation of an unexpected inhibitor binding mode. Bioorg.Med.Chem.Lett., 20, 2010
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2OO8
| Synthesis, Structural Analysis, and SAR Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors | 分子名称: | Angiopoietin-1 receptor, N-{3-[3-(DIMETHYLAMINO)PROPYL]-5-(TRIFLUOROMETHYL)PHENYL}-4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]BENZAMIDE | 著者 | Bellon, S.F, Kim, J. | 登録日 | 2007-01-25 | 公開日 | 2007-03-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
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2OPH
| Human dipeptidyl peptidase IV in complex with an alpha amino acid inhibitor | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scapin, G, Weber, A.E, Duffy, J.L. | 登録日 | 2007-01-29 | 公開日 | 2007-05-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | 4-Aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV. Bioorg.Med.Chem.Lett., 17, 2007
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5C0S
| Crystal structure of a generation 4 influenza hemagglutinin stabilized stem in complex with the broadly neutralizing antibody CR6261 | 分子名称: | CR6261 antibody heavy chain, CR6261 antibody light chain, Hemagglutinin, ... | 著者 | Boyington, J.C, Kwong, P.D, Nabel, G.J, Mascola, J.R. | 登録日 | 2015-06-12 | 公開日 | 2015-09-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection. Nat. Med., 21, 2015
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6K7U
| Crystal structure of beta-2 microglobulin (beta2m) of Bat (Pteropus Alecto) | 分子名称: | Bat beta-2-microglobulin | 著者 | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | 登録日 | 2019-06-08 | 公開日 | 2019-09-18 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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2RL5
| Crystal structure of the VEGFR2 kinase domain in complex with a 2,3-dihydro-1,4-benzoxazine inhibitor | 分子名称: | N-(4-CHLOROPHENYL)-7-[(6,7-DIMETHOXYQUINOLIN-4-YL)OXY]-2,3-DIHYDRO-1,4-BENZOXAZINE-4-CARBOXAMIDE, Vascular endothelial growth factor receptor 2 | 著者 | Whittington, D.A, Long, A.M, Rose, P, Zhao, H. | 登録日 | 2007-10-18 | 公開日 | 2008-04-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis. J.Med.Chem., 51, 2008
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4OHL
| LEOPARD Syndrome-Associated SHP2/T468M mutant | 分子名称: | Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | 登録日 | 2014-01-17 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations. Biochemistry, 53, 2014
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4OHH
| LEOPARD Syndrome-Associated SHP2/Q506P mutant | 分子名称: | Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | 登録日 | 2014-01-17 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations. Biochemistry, 53, 2014
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4OHI
| LEOPARD Syndrome-Associated SHP2/Q510E mutant | 分子名称: | Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | 登録日 | 2014-01-17 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations. Biochemistry, 53, 2014
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7E23
| SARS-CoV-2 spike in complex with the CA521 neutralizing antibody Fab (focused refinement on Fab-RBD) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CA521 Heavy Chain, CA521 Light Chain, ... | 著者 | Liu, C, Song, D, Dou, C. | 登録日 | 2021-02-04 | 公開日 | 2021-05-05 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure and function analysis of a potent human neutralizing antibody CA521 FALA against SARS-CoV-2. Commun Biol, 4, 2021
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4OHE
| LEOPARD Syndrome-Associated SHP2/G464A mutant | 分子名称: | Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | 登録日 | 2014-01-17 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | 主引用文献 | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations. Biochemistry, 53, 2014
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8WMF
| Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein (closed-1 state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K. | 登録日 | 2023-10-03 | 公開日 | 2024-04-24 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant. Microbiol Immunol, 2024
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