8GYA

Crystal structure of Alongshan virus methyltransferase bound to Sinefungin

Summary for 8GYA

• Entry DOI: 10.2210/pdb8gya/pdb
• Descriptor: Methyltransferase, SINEFUNGIN (3 entities in total)
• Functional Keywords: methyltransferase, viral protein
• Biological source: Alongshan virus
• Total number of polymer chains: 2
• Total formula weight: 64473.71

Authors

Chen, H.,Lin, S.,Lu, G.W. (deposition date: 2022-09-21, release date: 2023-09-27, Last modification date: 2024-04-10)

• Primary citation: Chen, H.,Lin, S.,Yang, F.,Chen, Z.,Guo, L.,Yang, J.,Lin, X.,Wang, L.,Duan, Y.,Wen, A.,Zhang, X.,Dai, Y.,Yin, K.,Yuan, X.,Yu, C.,He, Y.,He, B.,Cao, Y.,Dong, H.,Li, J.,Zhao, Q.,Liu, Q.,Lu, G.; Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.; Plos Pathog., 19:e1011694-e1011694, 2023; PubMed: 37831643; DOI: 10.1371/journal.ppat.1011694

Experimental method

X-RAY DIFFRACTION (2.005 Å)