5C0S
Crystal structure of a generation 4 influenza hemagglutinin stabilized stem in complex with the broadly neutralizing antibody CR6261
Summary for 5C0S
Entry DOI | 10.2210/pdb5c0s/pdb |
Related | 3GBM 3GBN 4EVN 5C0R |
Descriptor | Hemagglutinin, Envelope glycoprotein, Fibritin fusion protein, CR6261 antibody heavy chain, CR6261 antibody light chain (3 entities in total) |
Functional Keywords | hemagglutinin, immunogen, trimer, complex, viral protein-immune system complex, viral protein/immune system |
Biological source | Influenza A virus, Human immunodeficiency virus type 1 group M subtype B, Enterobacteria phage T4 More |
Total number of polymer chains | 3 |
Total formula weight | 81450.67 |
Authors | Boyington, J.C.,Kwong, P.D.,Nabel, G.J.,Mascola, J.R. (deposition date: 2015-06-12, release date: 2015-09-02, Last modification date: 2023-09-27) |
Primary citation | Yassine, H.M.,Boyington, J.C.,McTamney, P.M.,Wei, C.J.,Kanekiyo, M.,Kong, W.P.,Gallagher, J.R.,Wang, L.,Zhang, Y.,Joyce, M.G.,Lingwood, D.,Moin, S.M.,Andersen, H.,Okuno, Y.,Rao, S.S.,Harris, A.K.,Kwong, P.D.,Mascola, J.R.,Nabel, G.J.,Graham, B.S. Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection. Nat. Med., 21:1065-1070, 2015 Cited by PubMed: 26301691DOI: 10.1038/nm.3927 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.3 Å) |
Structure validation
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