1D60
 
 | | THE STRUCTURE OF THE B-DNA DECAMER C-C-A-A-C-I-T-T-G-G: TRIGONAL FORM | | 分子名称: | DNA (5'-D(*CP*CP*AP*AP*CP*IP*TP*TP*GP*G)-3'), MAGNESIUM ION | | 著者 | Lipanov, A, Kopka, M.L, Kaczor-Grzeskowiak, M, Quintana, J, Dickerson, R.E. | | 登録日 | 1992-02-26 | | 公開日 | 1993-04-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the B-DNA decamer C-C-A-A-C-I-T-T-G-G in two different space groups: conformational flexibility of B-DNA.
Biochemistry, 32, 1993
|
|
1GHK
 | | SOLUTION STRUCTURE OF THE LIPOYL DOMAIN OF THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX FROM AZOTOBACTER VINELAND II, NMR, 25 STRUCTURES | | 分子名称: | E2, THE DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX | | 著者 | Berg, A, Vervoort, J, De Kok, A. | | 登録日 | 1996-01-16 | | 公開日 | 1997-01-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the lipoyl domain of the 2-oxoglutarate dehydrogenase complex from Azotobacter vinelandii.
J.Mol.Biol., 261, 1996
|
|
4GUZ
 | | Structure of the arylamine N-acetyltransferase from Mycobacterium abscessus | | 分子名称: | Probable arylamine n-acetyl transferase | | 著者 | Kubiak, X, Li de la Sierra-Gallay, I, Haouz, A, Weber, P, Rodrigues-Lima, F. | | 登録日 | 2012-08-30 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and functional characterization of an arylamine N-acetyltransferase from the pathogen Mycobacterium abscessus: differences from other mycobacterial isoforms and implications for selective inhibition.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
6YXW
 | | Affimer K3 - KRAS protein complex | | 分子名称: | Affimer K3, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Trinh, C.H, Haza, K.Z, Rao, A, Martin, H.L, Tiede, C, Edwards, T.A, McPherson, M.J, Tomlinson, D.C. | | 登録日 | 2020-05-04 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site.
Nat Commun, 12, 2021
|
|
2X1Q
 | | Gelsolin Nanobody | | 分子名称: | GELSOLIN NANOBODY | | 著者 | Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J. | | 登録日 | 2010-01-03 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | | 主引用文献 | A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction.
Cell.Mol.Life Sci., 67, 2010
|
|
1CE7
 | | MISTLETOE LECTIN I FROM VISCUM ALBUM | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (RIBOSOME-INACTIVATING PROTEIN TYPE II) | | 著者 | Krauspenhaar, R, Eschenburg, S, Perbandt, M, Kornilov, V, Konareva, N, Mikailova, I, Stoeva, S, Wacker, R, Maier, T, Singh, T.P, Mikhailov, A, Voelter, W, Betzel, C. | | 登録日 | 1999-03-18 | | 公開日 | 2000-03-20 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of mistletoe lectin I from Viscum album.
Biochem.Biophys.Res.Commun., 257, 1999
|
|
2X18
 | | The crystal structure of the PH domain of human AKT3 protein kinase | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, RAC-GAMMA SERINE/THREONINE-PROTEIN KINASE | | 著者 | Vollmar, M, Wang, J, Zhang, Y, Elkins, J.M, Burgess-Brown, N, Chaikuad, A, Pike, A.C.W, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S. | | 登録日 | 2009-12-22 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | The Crystal Structure of the Ph Domain of Human Akt3 Protein Kinase
To be Published
|
|
2IN3
 | | Crystal structure of a putative protein disulfide isomerase from Nitrosomonas europaea | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Hypothetical protein, ... | | 著者 | Cuff, M.E, Skarina, T, Onopriyenko, O, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2006-10-05 | | 公開日 | 2006-11-21 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of a putative protein disulfide isomerase from Nitrosomonas europaea
To be Published
|
|
6O3C
 | | Crystal structure of active Smoothened bound to SAG21k, cholesterol, and NbSmo8 | | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-chloro-4,7-difluoro-N-{[2-methoxy-5-(pyridin-4-yl)phenyl]methyl}-N-[trans-4-(methylamino)cyclohexyl]-1-benzothiophene-2-carboxamide, ... | | 著者 | Deshpande, I.S, Liang, J, Hedeen, D, Roberts, K.J, Zhang, Y, Ha, B, Latorraca, N.R, Faust, B, Dror, R.O, Beachy, P.A, Myers, B.R, Manglik, A. | | 登録日 | 2019-02-26 | | 公開日 | 2019-07-03 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Smoothened stimulation by membrane sterols drives Hedgehog pathway activity.
Nature, 571, 2019
|
|
3O4X
 | |
4PW4
 | | Crystal structure of Aminopeptidase N in complex with phosphonic acid analogue of homophenylalanine L-(R)-hPheP | | 分子名称: | Aminopeptidase N, GLYCEROL, IMIDAZOLE, ... | | 著者 | Nocek, B, Mulligan, R, Vassiliou, S, Berlicki, L, Mucha, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-03-18 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of Aminopeptidase N in complex with phosphonic analogs of homophenylalanine
TO BE PUBLISHED
|
|
6O2B
 | | Crystal structure of 4493 Fab in complex with circumsporozoite protein DND and anti-kappa VHH domain | | 分子名称: | 1,2-ETHANEDIOL, 4493 Fab heavy chain, 4493 Kappa light chain, ... | | 著者 | Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P. | | 登録日 | 2019-02-22 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
|
|
1CLV
 | | YELLOW MEAL WORM ALPHA-AMYLASE IN COMPLEX WITH THE AMARANTH ALPHA-AMYLASE INHIBITOR | | 分子名称: | CALCIUM ION, CHLORIDE ION, PROTEIN (ALPHA-AMYLASE INHIBITOR), ... | | 著者 | Pereira, P.J.B, Lozanov, V, Patthy, A, Huber, R, Bode, W, Pongor, S, Strobl, S. | | 登録日 | 1999-05-04 | | 公開日 | 2000-05-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Specific inhibition of insect alpha-amylases: yellow meal worm alpha-amylase in complex with the amaranth alpha-amylase inhibitor at 2.0 A resolution.
Structure Fold.Des., 7, 1999
|
|
8AMZ
 | | Spinach 19S proteasome | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1 homolog, 26S proteasome non-ATPase regulatory subunit 2 homolog, 26S proteasome regulatory subunit 7, ... | | 著者 | Kandolf, S, Grishkovskaya, I, Meinhart, A, Haselbach, D. | | 登録日 | 2022-08-04 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structure of the plant 26S proteasome
Plant Communications, 3, 2022
|
|
1TQP
 | |
8POL
 | | Crystal structure of Plasmodium falciparum Sub1 protease | | 分子名称: | CALCIUM ION, PHOSPHATE ION, Subtilisin-like protease 1 | | 著者 | Martinez, M, Bouillon, A, Haouz, A, Barale, J.C, Alzari, P.M. | | 登録日 | 2023-07-05 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls Plasmodium Sub1 activity before merozoite egress.
Mbio, 15, 2024
|
|
1CLF
 | | CLOSTRIDIUM PASTEURIANUM FERREDOXIN | | 分子名称: | FERREDOXIN, IRON/SULFUR CLUSTER | | 著者 | Bertini, I, Donaire, A, Feinberg, B.A, Luchinat, C, Piccioli, M, Yuan, H. | | 登録日 | 1995-06-21 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the oxidized 2[4Fe-4S] ferredoxin from Clostridium pasteurianum.
Eur.J.Biochem., 232, 1995
|
|
6NHY
 | | Structure of the transmembrane domain of the Death Receptor 5 mutant (G217Y) - Trimer Only | | 分子名称: | Tumor necrosis factor receptor superfamily member 10B | | 著者 | Chou, J.J, Pan, L, Zhao, L, Chen, W, Piai, A, Fu, T, Wu, H, Liu, Z. | | 登録日 | 2018-12-24 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
|
|
4XRW
 | | Crystal structure of the di-domain ARO/CYC BexL from the BE-7585A biosynthetic pathway | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BexL | | 著者 | Tsai, S.C, Caldara-Festin, G.M, Jackson, D.R, Aguilar, S, Patel, A, Nguyen, M, Sasaki, E, Valentic, T.R, Barajas, J.F, Vo, M, Khanna, A, Liu, H.-W. | | 登録日 | 2015-01-21 | | 公開日 | 2015-12-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
6NHW
 | | Structure of the transmembrane domain of the Death Receptor 5 - Dimer of Trimer | | 分子名称: | Tumor necrosis factor receptor superfamily member 10B | | 著者 | Chou, J.J, Pan, L, Fu, Q, Zhao, L, Chen, W, Piai, A, Fu, T, Wu, H. | | 登録日 | 2018-12-24 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
|
|
6NUG
 | | hGRNA4-28_3s | | 分子名称: | Granulin-4 | | 著者 | Dastpeyman, M, Bansal, P, Wilson, D, Loukas, A, Smout, M, Daly, N. | | 登録日 | 2019-02-01 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | hGRN4-28_3s
to be published
|
|
6ROT
 | | Thrombin in complex with MI2105 | | 分子名称: | (2~{S})-~{N}-[[5-chloranyl-2-(hydroxymethyl)phenyl]methyl]-1-[2-[(phenylmethyl)sulfonylamino]ethanoyl]pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | | 著者 | Sandner, A, Heine, A, Klebe, G. | | 登録日 | 2019-05-13 | | 公開日 | 2019-11-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.339 Å) | | 主引用文献 | Strategies for Late-Stage Optimization: Profiling Thermodynamics by Preorganization and Salt Bridge Shielding.
J.Med.Chem., 62, 2019
|
|
5YBF
 | | Crystal structure of the GluA2o LBD in complex with glutamate and HBT1 | | 分子名称: | 2-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanoylamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, ACETATE ION, GLUTAMIC ACID, ... | | 著者 | Sogabe, S, Igaki, S, Hirokawa, A, Zama, Y, Lane, W, Snell, G. | | 登録日 | 2017-09-04 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | HBT1, a Novel AMPA Receptor Potentiator with Lower Agonistic Effect, Avoided Bell-Shaped Response in In Vitro BDNF Production.
J. Pharmacol. Exp. Ther., 364, 2018
|
|
6O6O
 | | Structure of the regulator FasR from Mycobacterium tuberculosis | | 分子名称: | MYRISTIC ACID, TetR family transcriptional regulator | | 著者 | Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. | | 登録日 | 2019-03-07 | | 公開日 | 2020-03-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine.
Nat Commun, 11, 2020
|
|
2WOJ
 | | ADP-AlF4 complex of S. cerevisiae GET3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPASE GET3, MAGNESIUM ION, ... | | 著者 | Mateja, A, Szlachcic, A, Downing, M.E, Dobosz, M, Mariappan, M, Hegde, R.S, Keenan, R.J. | | 登録日 | 2009-07-26 | | 公開日 | 2009-08-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.994 Å) | | 主引用文献 | The Structural Basis of Tail-Anchored Membrane Protein Recognition by Get3.
Nature, 461, 2009
|
|
