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2X18

The crystal structure of the PH domain of human AKT3 protein kinase

Summary for 2X18
Entry DOI10.2210/pdb2x18/pdb
DescriptorRAC-GAMMA SERINE/THREONINE-PROTEIN KINASE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total)
Functional Keywordskinase, membrane, transferase, atp-binding
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus : Q9Y243
Total number of polymer chains8
Total formula weight115259.08
Authors
Vollmar, M.,Wang, J.,Zhang, Y.,Elkins, J.M.,Burgess-Brown, N.,Chaikuad, A.,Pike, A.C.W.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Knapp, S. (deposition date: 2009-12-22, release date: 2010-03-16, Last modification date: 2023-12-20)
Primary citationVollmar, M.,Wang, J.,Zhang, Y.,Elkins, J.M.,Burgess-Brown, N.,Chaikuad, A.,Pike, A.C.W.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Knapp, S.
The Crystal Structure of the Ph Domain of Human Akt3 Protein Kinase
To be Published,
Experimental method
X-RAY DIFFRACTION (1.46 Å)
Structure validation

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