2X18
The crystal structure of the PH domain of human AKT3 protein kinase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0035556 | biological_process | intracellular signal transduction |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0035556 | biological_process | intracellular signal transduction |
| C | 0004674 | molecular_function | protein serine/threonine kinase activity |
| C | 0035556 | biological_process | intracellular signal transduction |
| D | 0004674 | molecular_function | protein serine/threonine kinase activity |
| D | 0035556 | biological_process | intracellular signal transduction |
| E | 0004674 | molecular_function | protein serine/threonine kinase activity |
| E | 0035556 | biological_process | intracellular signal transduction |
| F | 0004674 | molecular_function | protein serine/threonine kinase activity |
| F | 0035556 | biological_process | intracellular signal transduction |
| G | 0004674 | molecular_function | protein serine/threonine kinase activity |
| G | 0035556 | biological_process | intracellular signal transduction |
| H | 0004674 | molecular_function | protein serine/threonine kinase activity |
| H | 0035556 | biological_process | intracellular signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EPE A 500 |
| Chain | Residue |
| A | PHE54 |
| A | SER55 |
| A | GLN78 |
| A | TRP79 |
| A | HOH2222 |
| A | HOH2223 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EPE E 500 |
| Chain | Residue |
| E | TRP79 |
| E | HOH2189 |
| E | PHE54 |
| E | SER55 |
| E | GLN78 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EPE F 500 |
| Chain | Residue |
| F | PHE54 |
| F | SER55 |
| F | GLN78 |
| F | TRP79 |
| F | HOH2112 |
| F | HOH2191 |
| F | HOH2192 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EPE H 500 |
| Chain | Residue |
| D | ASP44 |
| H | ASN53 |
| H | PHE54 |
| H | SER55 |
| H | GLN78 |
| H | TRP79 |
| H | HOH2209 |
| H | HOH2210 |
| H | HOH2211 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine; by PKC/PRKCZ => ECO:0000269|PubMed:12162751 |
| Chain | Residue | Details |
| A | VAL7 | |
| B | VAL7 | |
| C | VAL7 | |
| D | VAL7 | |
| E | VAL7 | |
| F | VAL7 | |
| G | VAL7 | |
| H | VAL7 |
