7F5M
| |
7F51
| Crystal structure of Hst2 in complex with 2'-O-Benzoyl ADP Ribose | 分子名称: | NAD-dependent protein deacetylase HST2, ZINC ION, [(2R,3R,4R,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2,4-bis(oxidanyl)oxolan-3-yl] benzoate | 著者 | Wang, D, Yan, F, Chen, Y. | 登録日 | 2021-06-21 | 公開日 | 2022-03-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Global profiling of regulatory elements in the histone benzoylation pathway. Nat Commun, 13, 2022
|
|
7C5D
| |
7E1A
| |
7EHW
| BRD4-BD1 in complex with LT-642-602 | 分子名称: | 1-[4-ethyl-2-methyl-5-(6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4 | 著者 | Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y. | 登録日 | 2021-03-30 | 公開日 | 2022-03-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | BRD4-BD1 in complex with LT-642-602 To Be Published
|
|
7EHY
| BRD4-BD1 in complex with LT-448-138 | 分子名称: | 1-[2,4-dimethyl-5-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4 | 著者 | Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y. | 登録日 | 2021-03-30 | 公開日 | 2022-03-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | BRD4-BD1 in complex with LT-642-602 To Be Published
|
|
7EIG
| BRD4-BD1 in complex with LT-730-903 | 分子名称: | 1-[5-(5-azanyl-1H-benzimidazol-2-yl)-2-methyl-4-phenyl-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4 | 著者 | Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y. | 登録日 | 2021-03-31 | 公開日 | 2022-04-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | BRD4-BD1 in complex with LT-730-903 To Be Published
|
|
7EIK
| RD4-BD1 in complex with LT-872-297 | 分子名称: | 1-[2-methyl-5-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-4-(1-methylpyrazol-4-yl)-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4 | 著者 | Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y. | 登録日 | 2021-03-31 | 公開日 | 2022-04-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | RD4-BD1 in complex with LT-872-297 To Be Published
|
|
7D4O
| cyclic trinucleotide synthase CdnD in complex with ATP and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-AMP-GMP synthase, ... | 著者 | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | 登録日 | 2020-09-24 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
|
|
7D48
| apo-form cyclic trinucleotide synthase CdnD | 分子名称: | Cyclic AMP-AMP-GMP synthase, SODIUM ION | 著者 | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | 登録日 | 2020-09-23 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
|
|
7D4J
| ddATP complex of cyclic trinucleotide synthase CdnD | 分子名称: | 2',3'-dideoxyadenosine triphosphate, Cyclic AMP-AMP-GMP synthase, MAGNESIUM ION | 著者 | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | 登録日 | 2020-09-24 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
|
|
7D4U
| ATP complex with double mutant cyclic trinucleotide synthase CdnD | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-AMP-GMP synthase | 著者 | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | 登録日 | 2020-09-24 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
|
|
7D4S
| apo-form cyclic trinucleotide synthase CdnD | 分子名称: | Cyclic AMP-AMP-GMP synthase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION | 著者 | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | 登録日 | 2020-09-24 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
|
|
7DV5
| |
7DD0
| |
7CAM
| SARS-CoV-2 main protease (Mpro) apo structure (space group P212121) | 分子名称: | 3C-like proteinase | 著者 | Wang, Y.C, Yang, C.S, Hou, M.H, Tsai, C.L, Chou, Y.Z, Chen, Y. | 登録日 | 2020-06-09 | 公開日 | 2021-05-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug. Am J Cancer Res, 10, 2020
|
|
7CB7
| 1.7A resolution structure of SARS-CoV-2 main protease (Mpro) in complex with broad-spectrum coronavirus protease inhibitor GC376 | 分子名称: | (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ... | 著者 | Wang, Y.C, Yang, C.S, Hou, M.H, Tsai, C.L, Chou, Y.Z, Chen, Y, Hung, M.C. | 登録日 | 2020-06-10 | 公開日 | 2021-05-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug. Am J Cancer Res, 10, 2020
|
|
7F8E
| |
7FBI
| Cryo-EM structure of EBV gB in complex with nAbs 3A3 and 3A5 | 分子名称: | 3A3 heavy chain, 3A3 light chain, 3A5 heavy chain, ... | 著者 | Zheng, Q, Li, S, Zha, Z, Hong, J, Chen, Y, Zhang, X. | 登録日 | 2021-07-10 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of EBV gB in complex with nAbs 3A3 and 3A5 To Be Published
|
|
1Q57
| The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7 | 分子名称: | DNA primase/helicase | 著者 | Toth, E.A, Li, Y, Sawaya, M.R, Cheng, Y, Ellenberger, T. | 登録日 | 2003-08-06 | 公開日 | 2003-11-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7 Mol.Cell, 12, 2003
|
|
7M71
| SARS-CoV-2 Spike:5A6 Fab complex I focused refinement | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 5A6 Fab heavy chain, Antibody 5A6 Fab light chain, ... | 著者 | Asarnow, D, Cheng, Y. | 登録日 | 2021-03-26 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia. Cell, 184, 2021
|
|
7M7B
| SARS-CoV-2 Spike:Fab 3D11 complex focused refinement | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 3D11 heavy chain, Antibody Fab 3D11 light chain, ... | 著者 | Asarnow, D, Cheng, Y. | 登録日 | 2021-03-27 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia. Cell, 184, 2021
|
|
8CXB
| Human PA28-20S (PA28-4a3b) | 分子名称: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | 著者 | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | 登録日 | 2022-05-20 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7NAQ
| Human PA200-20S proteasome complex | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Proteasome activator complex subunit 4, Proteasome subunit alpha type-1, ... | 著者 | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | 登録日 | 2021-06-22 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7NAP
| Human PA28-20S-PA28 proteasome complex | 分子名称: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | 著者 | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | 登録日 | 2021-06-22 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|