8XUU
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8XUS
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![BU of 8xus by Molmil](/molmil-images/mine/8xus) | JN.1 Spike Trimer in complex with heparan sulfate | 分子名称: | 2-O-sulfo-beta-L-altropyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yue, C, Liu, P. | 登録日 | 2024-01-14 | 公開日 | 2024-07-03 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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6QFF
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![BU of 6qff by Molmil](/molmil-images/mine/6qff) | Crystal Structure of Human Kallikrein 6 in complex with GSK144 | 分子名称: | 4-[(5-phenyl-1~{H}-imidazol-2-yl)methylamino]-2-(pyridin-3-ylmethoxy)benzenecarboximidamide, GLYCEROL, Kallikrein-6 | 著者 | Thorpe, J.H. | 登録日 | 2019-01-10 | 公開日 | 2019-05-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome. Acta Crystallogr.,Sect.F, 75, 2019
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6QFS
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![BU of 6qfs by Molmil](/molmil-images/mine/6qfs) | Chargeless variant of the Cellulose-binding domain from Cellulomonas fimi | 分子名称: | 1,2-ETHANEDIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ... | 著者 | Young, D.R, Hoejgaard, C, Messens, J, Winther, J.R. | 登録日 | 2019-01-10 | 公開日 | 2019-12-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Charge Interactions in a Highly Charge-depleted Protein J.Am.Chem.Soc., 2021
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6QHB
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![BU of 6qhb by Molmil](/molmil-images/mine/6qhb) | Crystal Structure of Human Kallikrein 6 in complex with GSK578724A | 分子名称: | GLYCEROL, Kallikrein-6, ~{N}-(4-carbamimidoylphenyl)-3-methoxy-2-oxidanyl-benzamide | 著者 | Thorpe, J.H. | 登録日 | 2019-01-16 | 公開日 | 2019-02-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome. Bioorg. Med. Chem. Lett., 29, 2019
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5WP3
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![BU of 5wp3 by Molmil](/molmil-images/mine/5wp3) | Crystal Structure of EED in complex with EB22 | 分子名称: | EB22, Polycomb protein EED, UNKNOWN ATOM OR ION | 著者 | Dong, C, Tempel, W, Zhu, L, Moody, J.D, Baker, D, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-08-03 | 公開日 | 2017-09-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5KZP
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8SAI
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![BU of 8sai by Molmil](/molmil-images/mine/8sai) | Cryo-EM structure of GPR34-Gi complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Yong, X.H, Zhao, C, Yan, W, Shao, Z.H. | 登録日 | 2023-04-01 | 公開日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Cryo-EM structures of human GPR34 enable the identification of selective antagonists. Proc.Natl.Acad.Sci.USA, 120, 2023
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8Y7Y
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![BU of 8y7y by Molmil](/molmil-images/mine/8y7y) | Local structure of HCoV-HKU1A spike in complex with TMPRSS2 and glycan | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Wang, H.F, Zhang, X, Lu, Y, Liu, X, Sun, L, Yang, H.T. | 登録日 | 2024-02-05 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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6WXL
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8Y88
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![BU of 8y88 by Molmil](/molmil-images/mine/8y88) | Structure of HCoV-HKU1C spike in the functionally anchored-2up conformation with 2TMPRSS2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y7X
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![BU of 8y7x by Molmil](/molmil-images/mine/8y7x) | Structure of HCoV-HKU1A spike in the functionally anchored-3up conformation with 3TMPRSS2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-05 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8C
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![BU of 8y8c by Molmil](/molmil-images/mine/8y8c) | Structure of HCoV-HKU1C spike in the inactive-closed conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8D
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![BU of 8y8d by Molmil](/molmil-images/mine/8y8d) | Structure of HCoV-HKU1C spike in the inactive-1up conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8I
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![BU of 8y8i by Molmil](/molmil-images/mine/8y8i) | Structure of HCoV-HKU1C spike in the glycan-activated-3up conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8G
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![BU of 8y8g by Molmil](/molmil-images/mine/8y8g) | Structure of HCoV-HKU1C spike in the glycan-activated-1up conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y87
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![BU of 8y87 by Molmil](/molmil-images/mine/8y87) | Structure of HCoV-HKU1C spike in the functionally anchored-1up conformation with 1TMPRSS2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y89
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![BU of 8y89 by Molmil](/molmil-images/mine/8y89) | Structure of HCoV-HKU1C spike in the functionally anchored-3up conformation with 2TMPRSS2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Wang, H.F, Zhang, X, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8E
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![BU of 8y8e by Molmil](/molmil-images/mine/8y8e) | Structure of HCoV-HKU1C spike in the inactive-2up conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8B
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![BU of 8y8b by Molmil](/molmil-images/mine/8y8b) | Local structure of HCoV-HKU1C spike in complex with TMPRSS2 and glycan | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Wang, H.F, Zhang, X, Lu, Y.C, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8H
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![BU of 8y8h by Molmil](/molmil-images/mine/8y8h) | Structure of HCoV-HKU1C spike in the glycan-activated-2up conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8A
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![BU of 8y8a by Molmil](/molmil-images/mine/8y8a) | Structure of HCoV-HKU1C spike in the functionally anchored-3up conformation with 3TMPRSS2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8J
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![BU of 8y8j by Molmil](/molmil-images/mine/8y8j) | Local structure of HCoV-HKU1C spike in complex with glycan | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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8Y8F
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![BU of 8y8f by Molmil](/molmil-images/mine/8y8f) | Structure of HCoV-HKU1C spike in the glycan-activated-closed conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | 登録日 | 2024-02-06 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
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3LYI
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![BU of 3lyi by Molmil](/molmil-images/mine/3lyi) | PWWP Domain of Human Bromodomain-Containing Protein 1 | 分子名称: | Bromodomain-containing protein 1, CYSTEINESULFONIC ACID | 著者 | Lam, R, Zeng, H, Ni, S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2010-02-26 | 公開日 | 2010-03-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and histone binding ability characterizations of human PWWP domains. Plos One, 6, 2011
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