4TV8
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![BU of 4tv8 by Molmil](/molmil-images/mine/4tv8) | Tubulin-Maytansine complex | 分子名称: | (3beta,4beta,5beta,10beta,11E,13E)-maytansine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Prota, A.E, Bargsten, K, Diaz, J.F, Marsh, M, Cuevas, C, Liniger, M, Neuhaus, C, Andreu, J.M, Altmann, K.H, Steinmetz, M.O. | 登録日 | 2014-06-26 | 公開日 | 2014-08-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | 主引用文献 | A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs. Proc.Natl.Acad.Sci.USA, 111, 2014
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4TY0
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![BU of 4ty0 by Molmil](/molmil-images/mine/4ty0) | Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with linear intermediate 5' pppA(3',5')pG | 分子名称: | ACETATE ION, Cyclic AMP-GMP synthase, MAGNESIUM ION, ... | 著者 | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | 登録日 | 2014-07-07 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity. Cell, 158, 2014
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4TXZ
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![BU of 4txz by Molmil](/molmil-images/mine/4txz) | Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with nonhydrolyzable GTP | 分子名称: | Cyclic AMP-GMP synthase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | 著者 | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | 登録日 | 2014-07-07 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity. Cell, 158, 2014
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4UAP
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![BU of 4uap by Molmil](/molmil-images/mine/4uap) | X-ray structure of GH31 CBM32-2 bound to GalNAc | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, CALCIUM ION, GLYCEROL, ... | 著者 | Grondin, J.M, Abe, K, Boraston, A.B, Smith, S.P. | 登録日 | 2014-08-11 | 公開日 | 2015-10-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens. PLoS ONE, 12, 2017
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4UCK
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![BU of 4uck by Molmil](/molmil-images/mine/4uck) | X-ray structure and activities of an essential Mononegavirales L- protein domain | 分子名称: | RNA-DIRECTED RNA POLYMERASE L, S-ADENOSYLMETHIONINE, ZINC ION | 著者 | Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. | 登録日 | 2014-12-03 | 公開日 | 2015-11-18 | 最終更新日 | 2019-04-24 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
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4UCZ
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![BU of 4ucz by Molmil](/molmil-images/mine/4ucz) | X-ray structure and activities of an essential Mononegavirales L- protein domain | 分子名称: | GUANOSINE, GUANOSINE-5'-TRIPHOSPHATE, RNA-DIRECTED RNA POLYMERASE L, ... | 著者 | Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. | 登録日 | 2014-12-05 | 公開日 | 2015-11-18 | 最終更新日 | 2019-04-24 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
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4U2V
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![BU of 4u2v by Molmil](/molmil-images/mine/4u2v) | Bak BH3-in-Groove dimer (GFP) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Green fluorescent protein,Bcl-2 homologous antagonist/killer | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2014-07-18 | 公開日 | 2014-09-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers. Mol.Cell, 55, 2014
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4TWS
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![BU of 4tws by Molmil](/molmil-images/mine/4tws) | Gadolinium Derivative of Tetragonal Hen Egg-White Lysozyme at 1.45 A Resolution | 分子名称: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, CHLORIDE ION, GADOLINIUM ATOM, ... | 著者 | Holton, J.M, Classen, S, Frankel, K.A, Tainer, J.A. | 登録日 | 2014-07-01 | 公開日 | 2014-08-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The R-factor gap in macromolecular crystallography: an untapped potential for insights on accurate structures. Febs J., 281, 2014
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4U2U
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4UIO
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![BU of 4uio by Molmil](/molmil-images/mine/4uio) | Structure of the Salmonella typhi Type I Dehydroquinase covalently inhibited by a 3-dehydroquinic acid derivative | 分子名称: | (1~{R},3~{R},4~{S},5~{R})-3-methyl-1,3,4,5-tetrakis(oxidanyl)cyclohexane-1-carboxylic acid, 3-DEHYDROQUINATE DEHYDRATASE, CHLORIDE ION, ... | 著者 | Otero, J.M, Llamas-Saiz, A.L, Tizon, L, Lence, E, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | 登録日 | 2015-03-30 | 公開日 | 2015-07-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct. J.Am.Chem.Soc., 137, 2015
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4UD0
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![BU of 4ud0 by Molmil](/molmil-images/mine/4ud0) | X-ray structure and activities of an essential Mononegavirales L- protein domain | 分子名称: | RNA-DIRECTED RNA POLYMERASE L, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | 著者 | Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. | 登録日 | 2014-12-05 | 公開日 | 2015-11-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
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4UCL
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![BU of 4ucl by Molmil](/molmil-images/mine/4ucl) | X-ray structure and activities of an essential Mononegavirales L- protein domain | 分子名称: | RNA-DIRECTED RNA POLYMERASE L, SULFATE ION, ZINC ION | 著者 | Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. | 登録日 | 2014-12-03 | 公開日 | 2015-11-18 | 最終更新日 | 2019-04-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
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4UCY
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![BU of 4ucy by Molmil](/molmil-images/mine/4ucy) | X-ray structure and activities of an essential Mononegavirales L- protein domain | 分子名称: | RNA-DIRECTED RNA POLYMERASE L, SULFATE ION, ZINC ION | 著者 | Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. | 登録日 | 2014-12-05 | 公開日 | 2015-11-18 | 最終更新日 | 2019-04-24 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
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4UC4
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4ULX
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![BU of 4ulx by Molmil](/molmil-images/mine/4ulx) | Crystal structure of ancestral thioredoxin, relative to the last common ancestor of the Cyanobacterial, Deinococcus and Thermus groups, LPBCA-L89K mutant. | 分子名称: | CHLORIDE ION, LPBCA-L89K THIOREDOXIN | 著者 | Gavira, J.A, Risso, V.A, Ibarra-Molero, B, Sanchez-Ruiz, J.M. | 登録日 | 2014-05-14 | 公開日 | 2014-11-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Mutational Studies on Resurrected Ancestral Proteins Reveal Conservation of Site-Specific Amino Acid Preferences Throughout Evolutionary History. Mol.Biol.Evol., 32, 2015
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4UEK
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![BU of 4uek by Molmil](/molmil-images/mine/4uek) | Galactitol-1-phosphate 5-dehydrogenase from E. coli with Tris within the active site. | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GALACTITOL-1-PHOSPHATE 5-DEHYDROGENASE, ZINC ION | 著者 | Benavente, R, Esteban-Torres, M, Kohring, G.W, Cortes-Cabrera, A, Gago, F, Acebron, I, de las Rivas, B, Munoz, R, Mancheno, J.M. | 登録日 | 2014-12-18 | 公開日 | 2015-07-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Enantioselective Oxidation of Galactitol 1-Phosphate by Galactitol-1-Phosphate 5-Dehydrogenase from Escherichia Coli Acta Crystallogr.,Sect.D, 71, 2015
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7MGQ
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![BU of 7mgq by Molmil](/molmil-images/mine/7mgq) | AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans | 分子名称: | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase, MAGNESIUM ION | 著者 | Wizrah, M.S, Chua, S.M.H, Luo, Z, Manik, M.K, Pan, M, Whyte, J.M, Robertson, A.B, Kappler, U, Kobe, B, Fraser, J.A. | 登録日 | 2021-04-13 | 公開日 | 2022-04-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans. J.Biol.Chem., 298, 2022
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3CCP
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![BU of 3ccp by Molmil](/molmil-images/mine/3ccp) | X-RAY STRUCTURES OF RECOMBINANT YEAST CYTOCHROME C PEROXIDASE AND THREE HEME-CLEFT MUTANTS PREPARED BY SITE-DIRECTED MUTAGENESIS | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, YEAST CYTOCHROME C PEROXIDASE | 著者 | Wang, J, Mauro, J.M, Edwards, S.L, Oatley, S.J, Fishel, L.A, Ashford, V.A, Xuong, N.-H, Kraut, J. | 登録日 | 1990-02-28 | 公開日 | 1991-07-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | X-ray structures of recombinant yeast cytochrome c peroxidase and three heme-cleft mutants prepared by site-directed mutagenesis. Biochemistry, 29, 1990
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1ZEI
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![BU of 1zei by Molmil](/molmil-images/mine/1zei) | CROSS-LINKED B28 ASP INSULIN | 分子名称: | CHLORIDE ION, INSULIN, M-CRESOL, ... | 著者 | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | 登録日 | 1998-07-14 | 公開日 | 1999-02-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues. Biochemistry, 37, 1998
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1VBE
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![BU of 1vbe by Molmil](/molmil-images/mine/1vbe) | POLIOVIRUS (TYPE 3, SABIN STRAIN, MUTANT 242-H2) COMPLEXED WITH R78206 | 分子名称: | (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3 | 著者 | Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M. | 登録日 | 1996-01-02 | 公開日 | 1996-07-11 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design. Curr.Biol., 4, 1994
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1ZEG
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![BU of 1zeg by Molmil](/molmil-images/mine/1zeg) | STRUCTURE OF B28 ASP INSULIN IN COMPLEX WITH PHENOL | 分子名称: | CHLORIDE ION, INSULIN, PHENOL, ... | 著者 | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | 登録日 | 1998-05-01 | 公開日 | 1998-07-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues. Biochemistry, 37, 1998
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1VBA
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![BU of 1vba by Molmil](/molmil-images/mine/1vba) | POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R78206 | 分子名称: | (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3 | 著者 | Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M. | 登録日 | 1996-01-02 | 公開日 | 1996-07-11 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design. Curr.Biol., 4, 1994
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1VBB
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![BU of 1vbb by Molmil](/molmil-images/mine/1vbb) | POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R80633 | 分子名称: | (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3 | 著者 | Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M. | 登録日 | 1996-01-02 | 公開日 | 1996-07-11 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design. Curr.Biol., 4, 1994
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1VBC
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![BU of 1vbc by Molmil](/molmil-images/mine/1vbc) | POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R77975 | 分子名称: | (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3 | 著者 | Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M. | 登録日 | 1996-01-02 | 公開日 | 1996-07-11 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design. Curr.Biol., 4, 1994
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3E4C
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![BU of 3e4c by Molmil](/molmil-images/mine/3e4c) | Procaspase-1 zymogen domain crystal structure | 分子名称: | Caspase-1, MAGNESIUM ION | 著者 | Elliott, J.M, Rouge, L, Wiesmann, C, Scheer, J.M. | 登録日 | 2008-08-11 | 公開日 | 2008-12-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of procaspase-1 zymogen domain reveals insight into inflammatory caspase autoactivation J.Biol.Chem., 284, 2009
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