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4ULX

Crystal structure of ancestral thioredoxin, relative to the last common ancestor of the Cyanobacterial, Deinococcus and Thermus groups, LPBCA-L89K mutant.

Summary for 4ULX
Entry DOI10.2210/pdb4ulx/pdb
Related4D27
DescriptorLPBCA-L89K THIOREDOXIN, CHLORIDE ION (3 entities in total)
Functional Keywordsoxidoreductase, ancestral
Biological sourceSYNTHETIC CONSTRUCT
Total number of polymer chains1
Total formula weight12057.36
Authors
Gavira, J.A.,Risso, V.A.,Ibarra-Molero, B.,Sanchez-Ruiz, J.M. (deposition date: 2014-05-14, release date: 2014-11-26, Last modification date: 2024-01-10)
Primary citationRisso, V.A.,Manssour-Triedo, F.,Delgado-Delgado, A.,Arco, R.,Barroso-Deljesus, A.,Ingles-Prieto, A.,Godoy-Ruiz, R.,Gavira, J.A.,Gaucher, E.A.,Ibarra-Molero, B.,Sanchez-Ruiz, J.M.
Mutational Studies on Resurrected Ancestral Proteins Reveal Conservation of Site-Specific Amino Acid Preferences Throughout Evolutionary History.
Mol.Biol.Evol., 32:440-, 2015
Cited by
PubMed: 25392342
DOI: 10.1093/MOLBEV/MSU312
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.35 Å)
Structure validation

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