8CX9
| Structure of the SARS-COV2 PLpro (C111S) in complex with a dimeric Ubv that inhibits activity by an unusual allosteric mechanism | 分子名称: | BROMIDE ION, CHLORIDE ION, Papain-like protease nsp3, ... | 著者 | Singer, A.U, Slater, C.L, Patel, A, Russel, R, Mark, B.L, Sidhu, S.S. | 登録日 | 2022-05-20 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site. Plos Pathog., 18, 2022
|
|
6Q0N
| Structure of the Erbin PDB domain in complex with a high-affinity peptide | 分子名称: | Erbin, peptide | 著者 | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | 登録日 | 2019-08-02 | 公開日 | 2019-11-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
|
|
6Q0U
| Structure of the Erbin PDZ variant E-6a with a high-affinity C-terminal peptide | 分子名称: | 1,2-ETHANEDIOL, Erbin, peptide | 著者 | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | 登録日 | 2019-08-02 | 公開日 | 2019-11-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
|
|
6Q0M
| Structure of Erbin PDZ derivative E-14 with a high-affinity peptide | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | 登録日 | 2019-08-02 | 公開日 | 2019-11-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
|
|
3M16
| Structure of a Transaldolase from Oleispira antarctica | 分子名称: | Transaldolase | 著者 | Singer, A.U, Kagan, O, Zhang, R, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-03-04 | 公開日 | 2010-06-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. Nat Commun, 4, 2013
|
|
2QH1
| Structure of TA289, a CBS-rubredoxin-like protein, in its Fe+2-bound state | 分子名称: | FE (II) ION, Hypothetical protein Ta0289 | 著者 | Singer, A.U, Proudfoot, M, Brown, G, Xu, L, Savchenko, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2007-06-29 | 公開日 | 2008-02-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain. J.Mol.Biol., 375, 2008
|
|
2PYU
| Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with IMP | 分子名称: | 1,2-ETHANEDIOL, INOSINIC ACID, Inosine Triphosphate Pyrophosphatase RdgB | 著者 | Singer, A.U, Proudfoot, M, Skarina, T, Savchenko, A, Yakunin, A.F. | 登録日 | 2007-05-16 | 公開日 | 2008-03-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli. J.Mol.Biol., 374, 2007
|
|
2Q16
| Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with ITP | 分子名称: | CALCIUM ION, HAM1 protein homolog, INOSINE 5'-TRIPHOSPHATE, ... | 著者 | Singer, A.U, Lam, R, Proudfoot, M, Skarina, T, Savchenko, A, Yakunin, A.F. | 登録日 | 2007-05-23 | 公開日 | 2008-02-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli. J.Mol.Biol., 374, 2007
|
|
3QVM
| The structure of olei00960, a hydrolase from Oleispira antarctica | 分子名称: | CALCIUM ION, CHLORIDE ION, Olei00960, ... | 著者 | Singer, A.U, Kagan, O, Kim, Y, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2011-02-25 | 公開日 | 2011-04-13 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. Nat Commun, 4, 2013
|
|
3OI7
| Structure of the structure of the H13A mutant of Ykr043C in complex with sedoheptulose-1,7-bisphosphate | 分子名称: | 1,2-ETHANEDIOL, 1,7-di-O-phosphono-beta-D-altro-hept-2-ulofuranose, GLYCEROL, ... | 著者 | Singer, A.U, Xu, X, Dong, A, Cui, H, Clasquin, M.F, Caudy, A.A, Edwards, A.M, Savchenko, A, Joachimiak, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-08-18 | 公開日 | 2010-11-17 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Riboneogenesis in yeast. Cell(Cambridge,Mass.), 145, 2011
|
|
3BRM
| Crystal structure of the covalent complex between the Bacillus subtilis glutaminase YbgJ and 5-oxo-L-norleucine formed by reaction of the protein with 6-diazo-5-oxo-L-norleucine | 分子名称: | 5-OXO-L-NORLEUCINE, Glutaminase 1 | 著者 | Singer, A.U, Kim, Y, Dementieva, I, Vinokour, E, Joachimiak, A, Savchenko, A, Yakunin, A. | 登録日 | 2007-12-21 | 公開日 | 2008-05-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis. Biochemistry, 47, 2008
|
|
3DRW
| Crystal Structure of a Phosphofructokinase from Pyrococcus horikoshii OT3 with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, ADP-specific phosphofructokinase, SODIUM ION | 著者 | Singer, A.U, Skarina, T, Kochinyan, S, Brown, G, Cuff, M.E, Edwards, A.M, Joachimiak, A, Savchenko, A, Yakunin, A.F, Jia, Z, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-07-11 | 公開日 | 2008-12-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | ADP-dependent 6-phosphofructokinase from Pyrococcus horikoshii OT3: structure determination and biochemical characterization of PH1645. J.Biol.Chem., 284, 2009
|
|
3G1Z
| Structure of IDP01693/yjeA, a potential t-RNA synthetase from Salmonella typhimurium | 分子名称: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, PHOSPHATE ION, ... | 著者 | Singer, A.U, Evdokimova, E, Kudritska, M, Cuff, M.E, Edwards, A.M, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-01-30 | 公開日 | 2009-03-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | PoxA, yjeK, and elongation factor P coordinately modulate virulence and drug resistance in Salmonella enterica. Mol.Cell, 39, 2010
|
|
3I4Q
| Structure of a putative inorganic pyrophosphatase from the oil-degrading bacterium Oleispira antarctica | 分子名称: | APC40078, SODIUM ION | 著者 | Singer, A.U, Evdokimova, E, Kagan, O, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2009-07-02 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. Nat Commun, 4, 2013
|
|
2KKX
| Solution Structure of C-terminal domain of reduced NleG2-3 (residues 90-191) from Pathogenic E. coli O157:H7. Northeast Structural Genomics Consortium and Midwest Center for Structural Genomics target ET109A | 分子名称: | Uncharacterized protein ECs2156 | 著者 | Wu, B, Yee, A, Fares, C, Lemak, A, Semest, A, Claude, M, Singer, A, Edwards, A, Savchenko, A, Montelione, G.T, Joachimiak, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2009-06-29 | 公開日 | 2009-08-25 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases. Plos Pathog., 6, 2010
|
|
2KKY
| Solution Structure of C-terminal domain of oxidized NleG2-3 (residue 90-191) from Pathogenic E. coli O157:H7. Northeast Structural Genomics Consortium and Midwest Center for Structural Genomics target ET109A | 分子名称: | Uncharacterized protein ECs2156 | 著者 | Wu, B, Yee, A, Fares, C, Lemak, A, Semest, A, Claude, M, Singer, A, Edwards, A, Savchenko, A, Montelione, G.T, Joachimiak, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG), Ontario Centre for Structural Proteomics (OCSP) | 登録日 | 2009-06-29 | 公開日 | 2009-08-25 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases. Plos Pathog., 6, 2010
|
|
2AZS
| NMR structure of the N-terminal SH3 domain of Drk (calculated without NOE restraints) | 分子名称: | SH2-SH3 adapter protein drk | 著者 | Bezsonova, I, Singer, A.U, Choy, W.-Y, Tollinger, M, Forman-Kay, J.D. | 登録日 | 2005-09-12 | 公開日 | 2005-12-13 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Comparison of the Unstable drkN SH3 Domain and a Stable Mutant Biochemistry, 44, 2005
|
|
2AZV
| Solution structure of the T22G mutant of N-terminal SH3 domain of DRK (calculated without NOEs) | 分子名称: | SH2-SH3 adapter protein drk | 著者 | Bezsonova, I, Singer, A.U, Choy, W.-Y, Tollinger, M, Forman-Kay, J.D. | 登録日 | 2005-09-12 | 公開日 | 2005-12-13 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Comparison of the Unstable drkN SH3 Domain and a Stable Mutant Biochemistry, 44, 2005
|
|
1TCE
| SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | PHOSPHOPEPTIDE OF THE ZETA CHAIN OF T CELL RECEPTOR, SHC | 著者 | Zhou, M.-M, Meadows, R.P, Logan, T.M, Yoon, H.S, Wade, W.R, Ravichandran, K.S, Burakoff, S.J, Feisk, S.W. | 登録日 | 1996-03-27 | 公開日 | 1997-05-15 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor. Proc.Natl.Acad.Sci.USA, 92, 1995
|
|
3S8Y
| Bromide soaked structure of an esterase from the oil-degrading bacterium Oleispira antarctica | 分子名称: | BROMIDE ION, Esterase APC40077 | 著者 | Petit, P, Dong, A, Kagan, O, Savchenko, A, Yakunin, A.F. | 登録日 | 2011-05-31 | 公開日 | 2011-06-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and activity of the cold-active and anion-activated carboxyl esterase OLEI01171 from the oil-degrading marine bacterium Oleispira antarctica. Biochem.J., 445, 2012
|
|
3Q3C
| Crystal structure of a serine dehydrogenase from Pseudomonas aeruginosa pao1 in complex with NAD | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Probable 3-hydroxyisobutyrate dehydrogenase | 著者 | Tan, K, Singer, A.U, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-12-21 | 公開日 | 2011-02-23 | 最終更新日 | 2012-02-01 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Biochemical and Structural Studies of Uncharacterized Protein PA0743 from Pseudomonas aeruginosa Revealed NAD+-dependent L-Serine Dehydrogenase. J.Biol.Chem., 287, 2012
|
|
3OBB
| Crystal structure of a possible 3-hydroxyisobutyrate Dehydrogenase from pseudomonas aeruginosa pao1 | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ... | 著者 | Tan, K, Singer, A.U, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Yakunin, A.F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-08-06 | 公開日 | 2010-08-18 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Biochemical and Structural Studies of Uncharacterized Protein PA0743 from Pseudomonas aeruginosa Revealed NAD+-dependent L-Serine Dehydrogenase. J.Biol.Chem., 287, 2012
|
|
8T6I
| Structure of VHH-Fab complex with engineered Crystal Kappa region | 分子名称: | Fab heavy chain, Fab light chain, GLYCEROL, ... | 著者 | Filippova, E.V, Thompson, I, Kossiakoff, A.A. | 登録日 | 2023-06-16 | 公開日 | 2023-11-29 | 最終更新日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
|
|
8T9Y
| Structure of VHH-Fab complex with engineered Elbow FNQIKG and Crystal Kappa regions | 分子名称: | DI(HYDROXYETHYL)ETHER, Fab heavy chain, Fab light chain, ... | 著者 | Filippova, E.V, Thompson, I, Kossiakoff, A.A. | 登録日 | 2023-06-26 | 公開日 | 2023-11-29 | 最終更新日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
|
|
8T58
| |