6Q0U

Structure of the Erbin PDZ variant E-6a with a high-affinity C-terminal peptide

Summary for 6Q0U

Entry DOI	10.2210/pdb6q0u/pdb
Related	1N7T 6Q0N
Descriptor	Erbin, peptide, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	peptide-phage display, protein engineering, pdz domains, c-terminal peptide, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	22505.40
Authors	Singer, A.U.,Teyra, J.,Ernst, A.,Sicheri, F.,Sidhu, S.S. (deposition date: 2019-08-02, release date: 2019-11-13, Last modification date: 2024-04-03)
Primary citation	Teyra, J.,Ernst, A.,Singer, A.,Sicheri, F.,Sidhu, S.S. Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29:433-442, 2020 Cited by PubMed: 31654425 DOI: 10.1002/pro.3759 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation