6Q0U

Structure of the Erbin PDZ variant E-6a with a high-affinity C-terminal peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Erbin	polymer	94	10273.7	2	UniProt (Q96RT1) Pfam (PF00595) In PDB	Homo sapiens (Human)	Densin-180-like protein,Erbb2-interacting protein,Protein LAP2
2	C, D	peptide	polymer	7	917.0	2		synthetic construct
3	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4		water	water		18.0	134	Chemie (HOH)

Sequence modifications

A, B: 3 - 92 (UniProt: Q96RT1)

PDB	External Database	Details
Ser -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag
Met 2	-	expression tag
Arg 17	Ser 1294	engineered mutation
Ala 19	Ser 1296	engineered mutation
Ile 74	Val 1351	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	22381.3
Non-Polymers*	Number of molecules	2
	Total formula weight	124.1
All*	Total formula weight	22505.4

*Water molecules are not included.