6Q0U
Structure of the Erbin PDZ variant E-6a with a high-affinity C-terminal peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Erbin | polymer | 94 | 10273.7 | 2 | UniProt (Q96RT1) Pfam (PF00595) | Homo sapiens (Human) | Densin-180-like protein,Erbb2-interacting protein,Protein LAP2 |
| 2 | C, D (C, D) | peptide | polymer | 7 | 917.0 | 2 | synthetic construct | ||
| 3 | E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 92 (UniProt: Q96RT1)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Met 2 | - | expression tag |
| Arg 17 | Ser 1294 | engineered mutation |
| Ala 19 | Ser 1296 | engineered mutation |
| Ile 74 | Val 1351 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 22381.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 124.1 | |
| All* | Total formula weight | 22505.4 |
