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7N6P
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BU of 7n6p by Molmil
Crystal structure of the anti-EBOV and SUDV monoclonal antibody 1C3 Fab
分子名称: 1C3 Fab heavy chain, 1C3 Fab light chain
著者Milligan, J.C, Yu, X, Buck, T, Saphire, E.O.
登録日2021-06-08
公開日2022-04-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses.
Cell, 185, 2022
7K7J
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BU of 7k7j by Molmil
EphB6 receptor ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 6
著者Goldgur, Y, Himanen, J.
登録日2020-09-22
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献Structure of the EphB6 receptor ectodomain.
Plos One, 16, 2021
7KFB
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BU of 7kfb by Molmil
Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-442
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab EBOV-442 heavy chain, ...
著者Murin, C.D, Ward, A.B.
登録日2020-10-13
公開日2021-04-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
7KEW
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BU of 7kew by Molmil
Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-43
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BDBV-43 Fab heavy chain, ...
著者Murin, C.D, Ward, A.B.
登録日2020-10-13
公開日2021-04-28
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
7KFG
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BU of 7kfg by Molmil
Antibody Fab BDBV-289
分子名称: Antibody Fab BDBV-289 heavy chain, Antibody Fab BDBV-289 light chain, DI(HYDROXYETHYL)ETHER
著者Murin, C.D, Bruhn, J.F, Ward, A.B.
登録日2020-10-13
公開日2021-04-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.002 Å)
主引用文献Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
7KEX
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BU of 7kex by Molmil
Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-293
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab EBOV-293 heavy chain, Antibody Fab EBOV-293 light chain, ...
著者Murin, C.D, Ward, A.B.
登録日2020-10-13
公開日2021-04-28
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
7KFE
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BU of 7kfe by Molmil
Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-329
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody BDBV-329 heavy chain, ...
著者Murin, C.D, Ward, A.B.
登録日2020-10-13
公開日2021-04-28
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
7KF9
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BU of 7kf9 by Molmil
Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-296 and EBOV-515
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab EBOV-296 heavy chain, Antibody Fab EBOV-296 light chain, ...
著者Murin, C.D, Ward, A.B.
登録日2020-10-13
公開日2021-04-28
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
7KEJ
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BU of 7kej by Molmil
BDBV-289 bound to EBOV GPdMuc Makona
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain (HC) BDBV-289, Antibody Fab light chain (LC) BDBV-289, ...
著者Murin, C.D, Ward, A.B.
登録日2020-10-11
公開日2021-06-23
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
7KFH
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BU of 7kfh by Molmil
Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-437
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab EBOV-437 heavy chain, ...
著者Murin, C.D, Ward, A.B.
登録日2020-10-13
公開日2021-04-28
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
2QCL
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BU of 2qcl by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP
分子名称: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCC
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BU of 2qcc by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase, apo form
分子名称: GLYCEROL, Orotidine 5'- phosphate decarboxylase (OMPdecase), SULFATE ION
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCM
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BU of 2qcm by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 6-hydroxymethyl-UMP
分子名称: 6-(HYDROXYMETHYL)URIDINE 5'-(DIHYDROGEN PHOSPHATE), Uridine 5'-monophosphate synthase (UMP synthase)
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCG
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BU of 2qcg by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-bromo-UMP
分子名称: 5-BROMO-URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCH
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BU of 2qch by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-iodo-UMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, IODIDE ION, ...
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCN
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BU of 2qcn by Molmil
Covalent complex of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase with 6-iodo-UMP
分子名称: GLYCEROL, SULFATE ION, URIDINE-5'-MONOPHOSPHATE, ...
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCD
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BU of 2qcd by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to UMP
分子名称: URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCF
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BU of 2qcf by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP
分子名称: 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, Uridine 5'-monophosphate synthase (UMP synthase)
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCE
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BU of 2qce by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to sulfate, glycerol, and chloride
分子名称: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
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