7KF9

Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-296 and EBOV-515

Summary for 7KF9

• Entry DOI: 10.2210/pdb7kf9/pdb
• EMDB information: 22847
• Descriptor: Antibody Fab EBOV-296 heavy chain, Virion spike glycoprotein 1, Virion spike glycoprotein 2, ... (6 entities in total)
• Functional Keywords: ebolavirus, antibody, broadly neutralizing, glycan cap, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 332300.83

Authors

Murin, C.D.,Ward, A.B. (deposition date: 2020-10-13, release date: 2021-04-28)

• Primary citation: Murin, C.D.,Gilchuk, P.,Ilinykh, P.A.,Huang, K.,Kuzmina, N.,Shen, X.,Bruhn, J.F.,Bryan, A.L.,Davidson, E.,Doranz, B.J.,Williamson, L.E.,Copps, J.,Alkutkar, T.,Flyak, A.I.,Bukreyev, A.,Crowe Jr., J.E.,Ward, A.B.; Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.; Cell Rep, 35:108984-108984, 2021; PubMed: 33852862; DOI: 10.1016/j.celrep.2021.108984

Experimental method

ELECTRON MICROSCOPY (4.4 Å)