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7KF9

Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-296 and EBOV-515

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1G, I, HAntibody Fab EBOV-296 heavy chainpolymer25427260.93Homo sapiens (human)
2A, C, BVirion spike glycoprotein 1polymer31334978.63UniProt (A0A1C4HDV6)
Pfam (PF01611)
UniProt (by SIFTS) (Q05320)
In PDB
Ebola virus
3D, F, EVirion spike glycoprotein 2polymer20322158.63UniProt (A0A0E3XK95)
Pfam (PF22307)
UniProt (by SIFTS) (Q05320)
In PDB
Ebola virus
4J, L, KAntibody Fab EBOV-296 light chainpolymer23424794.43Homo sapiens (human)
5M, N, Oalpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.83In PDB
GlyTouCan (G22768VO)
6A, C, B2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.29Chemie (NAG)
Sequence modifications
A, C, B: 32 - 309 (UniProt: A0A1C4HDV6)
PDBExternal DatabaseDetails
Met -3-expression tag
Asp -2-expression tag
Ala -1-expression tag
Met 0-expression tag
Lys 1-expression tag
Arg 2-expression tag
Gly 3-expression tag
Leu 4-expression tag
Cys 5-expression tag
Cys 6-expression tag
Val 7-expression tag
Leu 8-expression tag
Leu 9-expression tag
Leu 10-expression tag
Cys 11-expression tag
Gly 12-expression tag
Ala 13-expression tag
Val 14-expression tag
Phe 15-expression tag
Val 16-expression tag
Ser 17-expression tag
Pro 18-expression tag
Ser 19-expression tag
Gln 20-expression tag
Glu 21-expression tag
Ile 22-expression tag
His 23-expression tag
Ala 24-expression tag
Arg 25-expression tag
Phe 26-expression tag
Arg 27-expression tag
Arg 28-expression tag
Gly 29-expression tag
Ala 30-expression tag
Arg 31-expression tag
D, F, E: 461 - 629 (UniProt: A0A0E3XK95)
PDBExternal DatabaseDetails
Asp 630-expression tag
Asp 631-expression tag
Asp 632-expression tag
Lys 633-expression tag
Ala 634-expression tag
Gly 635-expression tag
Trp 636-expression tag
Ser 637-expression tag
His 638-expression tag
Pro 639-expression tag
Gln 640-expression tag
Phe 641-expression tag
Glu 642-expression tag
Lys 643-expression tag
Gly 644-expression tag
Gly 645-expression tag
Gly 646-expression tag
Ser 647-expression tag
Gly 648-expression tag
Gly 649-expression tag
Gly 650-expression tag
Ser 651-expression tag
Gly 652-expression tag
Gly 653-expression tag
Gly 654-expression tag
Ser 655-expression tag
Trp 656-expression tag
Ser 657-expression tag
His 658-expression tag
Pro 659-expression tag
Gln 660-expression tag
Phe 661-expression tag
Glu 662-expression tag
Lys 663-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight327577.5
BranchedNumber of molecules3
Total formula weight2732.5
Non-Polymers*Number of molecules9
Total formula weight1990.9
All*Total formula weight332300.8
*Water molecules are not included.

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PDB entries from 2024-07-17

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