7KF9
Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-296 and EBOV-515
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (G, I, H) | Antibody Fab EBOV-296 heavy chain | polymer | 254 | 27260.9 | 3 | Homo sapiens (human) | ||
| 2 | B, F, J (A, C, B) | Virion spike glycoprotein 1 | polymer | 313 | 34978.6 | 3 | UniProt (A0A1C4HDV6) Pfam (PF01611) UniProt (by SIFTS) (Q05320) | Ebola virus | |
| 3 | C, G, K (D, F, E) | Virion spike glycoprotein 2 | polymer | 203 | 22158.6 | 3 | UniProt (A0A0E3XK95) Pfam (PF22307) UniProt (by SIFTS) (Q05320) | Ebola virus | |
| 4 | D, H, L (J, L, K) | Antibody Fab EBOV-296 light chain | polymer | 234 | 24794.4 | 3 | Homo sapiens (human) | ||
| 5 | M, N, O (M, N, O) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 6 | P, Q, R, S, T... (A, C, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) |
Sequence modifications
A, C, B: 32 - 309 (UniProt: A0A1C4HDV6)
D, F, E: 461 - 629 (UniProt: A0A0E3XK95)
| PDB | External Database | Details |
|---|---|---|
| Met -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Met 0 | - | expression tag |
| Lys 1 | - | expression tag |
| Arg 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Cys 5 | - | expression tag |
| Cys 6 | - | expression tag |
| Val 7 | - | expression tag |
| Leu 8 | - | expression tag |
| Leu 9 | - | expression tag |
| Leu 10 | - | expression tag |
| Cys 11 | - | expression tag |
| Gly 12 | - | expression tag |
| Ala 13 | - | expression tag |
| Val 14 | - | expression tag |
| Phe 15 | - | expression tag |
| Val 16 | - | expression tag |
| Ser 17 | - | expression tag |
| Pro 18 | - | expression tag |
| Ser 19 | - | expression tag |
| Gln 20 | - | expression tag |
| Glu 21 | - | expression tag |
| Ile 22 | - | expression tag |
| His 23 | - | expression tag |
| Ala 24 | - | expression tag |
| Arg 25 | - | expression tag |
| Phe 26 | - | expression tag |
| Arg 27 | - | expression tag |
| Arg 28 | - | expression tag |
| Gly 29 | - | expression tag |
| Ala 30 | - | expression tag |
| Arg 31 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp 630 | - | expression tag |
| Asp 631 | - | expression tag |
| Asp 632 | - | expression tag |
| Lys 633 | - | expression tag |
| Ala 634 | - | expression tag |
| Gly 635 | - | expression tag |
| Trp 636 | - | expression tag |
| Ser 637 | - | expression tag |
| His 638 | - | expression tag |
| Pro 639 | - | expression tag |
| Gln 640 | - | expression tag |
| Phe 641 | - | expression tag |
| Glu 642 | - | expression tag |
| Lys 643 | - | expression tag |
| Gly 644 | - | expression tag |
| Gly 645 | - | expression tag |
| Gly 646 | - | expression tag |
| Ser 647 | - | expression tag |
| Gly 648 | - | expression tag |
| Gly 649 | - | expression tag |
| Gly 650 | - | expression tag |
| Ser 651 | - | expression tag |
| Gly 652 | - | expression tag |
| Gly 653 | - | expression tag |
| Gly 654 | - | expression tag |
| Ser 655 | - | expression tag |
| Trp 656 | - | expression tag |
| Ser 657 | - | expression tag |
| His 658 | - | expression tag |
| Pro 659 | - | expression tag |
| Gln 660 | - | expression tag |
| Phe 661 | - | expression tag |
| Glu 662 | - | expression tag |
| Lys 663 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 327577.5 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2732.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1990.9 | |
| All* | Total formula weight | 332300.8 |
