5M3O
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2ODY
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![BU of 2ody by Molmil](/molmil-images/mine/2ody) | Thrombin-bound boophilin displays a functional and accessible reactive-site loop | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Boophilin, PHOSPHATE ION, ... | 著者 | Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. | 登録日 | 2006-12-27 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick. Plos One, 3, 2008
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4WZY
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![BU of 4wzy by Molmil](/molmil-images/mine/4wzy) | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway (ATP complex) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltokinase | 著者 | Fraga, J, Empadinhas, N, Pereira, P.J.B, Macedo-Ribeiro, S. | 登録日 | 2014-11-20 | 公開日 | 2015-02-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway. Sci Rep, 5, 2015
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3QNE
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![BU of 3qne by Molmil](/molmil-images/mine/3qne) | Candida albicans seryl-tRNA synthetase | 分子名称: | Seryl-tRNA synthetase, cytoplasmic | 著者 | Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S. | 登録日 | 2011-02-08 | 公開日 | 2011-08-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen. Proc.Natl.Acad.Sci.USA, 108, 2011
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3QO5
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![BU of 3qo5 by Molmil](/molmil-images/mine/3qo5) | Crystal Structure of the seryl-tRNA synthetase from Candida albicans | 分子名称: | Seryl-tRNA synthetase, cytoplasmic | 著者 | Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S. | 登録日 | 2011-02-09 | 公開日 | 2011-08-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen. Proc.Natl.Acad.Sci.USA, 108, 2011
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3QO7
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![BU of 3qo7 by Molmil](/molmil-images/mine/3qo7) | Crystal structure of the seryl-tRNA synthetase from Candida albicans | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Seryl-tRNA synthetase, cytoplasmic | 著者 | Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S. | 登録日 | 2011-02-09 | 公開日 | 2011-08-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen. Proc.Natl.Acad.Sci.USA, 108, 2011
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3QO8
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![BU of 3qo8 by Molmil](/molmil-images/mine/3qo8) | Crystal Structure of seryl-tRNA synthetase from Candida albicans | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Seryl-tRNA synthetase, ... | 著者 | Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S. | 登録日 | 2011-02-09 | 公開日 | 2011-08-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen. Proc.Natl.Acad.Sci.USA, 108, 2011
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1X7T
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![BU of 1x7t by Molmil](/molmil-images/mine/1x7t) | Structure of TTR R104H: a non-amyloidogenic variant with protective clinical effects | 分子名称: | Transthyretin | 著者 | Neto-Silva, R.M, Macedo-Ribeiro, S, Pereira, P.J.B, Coll, M, Saraiva, M.J, Damas, A.M. | 登録日 | 2004-08-16 | 公開日 | 2005-03-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis. Acta Crystallogr.,Sect.D, 61, 2005
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1X7S
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![BU of 1x7s by Molmil](/molmil-images/mine/1x7s) | The X-ray crystallographic structure of the amyloidogenic variant TTR Tyr78Phe | 分子名称: | Transthyretin | 著者 | Neto-Silva, R.M, Macedo-Ribeiro, S, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | 登録日 | 2004-08-16 | 公開日 | 2005-03-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis. Acta Crystallogr.,Sect.D, 61, 2005
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4U98
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![BU of 4u98 by Molmil](/molmil-images/mine/4u98) | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway (AppCp complex) | 分子名称: | MAGNESIUM ION, Maltokinase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Fraga, J, Empadinhas, N, Pereira, P.J.B, Macedo-Ribeiro, S. | 登録日 | 2014-08-05 | 公開日 | 2015-02-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway. Sci Rep, 5, 2015
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4U94
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![BU of 4u94 by Molmil](/molmil-images/mine/4u94) | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway | 分子名称: | MAGNESIUM ION, Maltokinase | 著者 | Fraga, J, Empadinhas, N, Pereira, P.J.B, Macedo-Ribeiro, S. | 登録日 | 2014-08-05 | 公開日 | 2015-02-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.473 Å) | 主引用文献 | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway. Sci Rep, 5, 2015
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4E05
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![BU of 4e05 by Molmil](/molmil-images/mine/4e05) | Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Salivary anti-thrombin peptide anophelin, ... | 著者 | Figueiredo, A.C, de Sanctis, D, Gutierrez-Gallego, R, Cereija, T.B, Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. | 登録日 | 2012-03-02 | 公開日 | 2012-12-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.304 Å) | 主引用文献 | Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector. Proc.Natl.Acad.Sci.USA, 109, 2012
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4E06
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![BU of 4e06 by Molmil](/molmil-images/mine/4e06) | Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Salivary anti-thrombin peptide anophelin, ... | 著者 | Figueiredo, A.C, de Sanctis, D, Gutierrez-Gallego, R, Cereija, T.B, Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. | 登録日 | 2012-03-02 | 公開日 | 2012-12-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.196 Å) | 主引用文献 | Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector. Proc.Natl.Acad.Sci.USA, 109, 2012
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1T31
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![BU of 1t31 by Molmil](/molmil-images/mine/1t31) | A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E, Pereira, P.J.B, Wang, Z.M, Rubin, H, Huber, R, Bode, W, Schechter, N.M, Strobl, S. | 登録日 | 2004-04-23 | 公開日 | 2005-03-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J.Biol.Chem., 280, 2005
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5TO1
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![BU of 5to1 by Molmil](/molmil-images/mine/5to1) | HtrA2 exposed (L266R, F303A) mutant | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Serine protease HTRA2, ... | 著者 | Merski, M, Barbosa Pereira, P.J, Macedo-Ribeiro, S. | 登録日 | 2016-10-15 | 公開日 | 2017-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2. Cell Death Dis, 8, 2017
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5TNY
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![BU of 5tny by Molmil](/molmil-images/mine/5tny) | HTRA2 G399S mutant | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Serine protease HTRA2, mitochondrial | 著者 | Merski, M, Barbosa Pereira, P.J, Macedo-Ribeiro, S. | 登録日 | 2016-10-15 | 公開日 | 2017-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2. Cell Death Dis, 8, 2017
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5TO0
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![BU of 5to0 by Molmil](/molmil-images/mine/5to0) | HTRA2 S276C mutant | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Serine protease HTRA2, mitochondrial | 著者 | Merski, M, Barbosa Pereira, P.J, Macedo-Ribeiro, S. | 登録日 | 2016-10-15 | 公開日 | 2017-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2. Cell Death Dis, 8, 2017
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3U8T
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![BU of 3u8t by Molmil](/molmil-images/mine/3u8t) | Human thrombin complexed with D-Phe-Pro-D-Arg-Cys | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Figueiredo, A.C, Clement, C.C, Philipp, M, Pereira, P.J.B. | 登録日 | 2011-10-17 | 公開日 | 2012-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.861 Å) | 主引用文献 | Rational design and characterization of d-phe-pro-d-arg-derived direct thrombin inhibitors. Plos One, 7, 2012
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3U8O
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![BU of 3u8o by Molmil](/molmil-images/mine/3u8o) | Human thrombin complexed with D-Phe-Pro-D-Arg-D-Thr | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Figueiredo, A.C, Clement, C.C, Philipp, M, Pereira, P.J.B. | 登録日 | 2011-10-17 | 公開日 | 2012-05-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors. Plos One, 7, 2012
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3U8R
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![BU of 3u8r by Molmil](/molmil-images/mine/3u8r) | Human thrombin complexed with D-Phe-Pro-D-Arg-Ile | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Figueiredo, A.C, Clement, C.C, Philipp, M, Pereira, P.J.B. | 登録日 | 2011-10-17 | 公開日 | 2012-05-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors. Plos One, 7, 2012
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4BOH
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![BU of 4boh by Molmil](/molmil-images/mine/4boh) | Madanins (MEROPS I53) are cleaved by thrombin and factor Xa | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, SULFATE ION, ... | 著者 | Figueiredo, A.C, deSanctis, D, Pereira, P.J.B. | 登録日 | 2013-05-20 | 公開日 | 2013-09-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | 主引用文献 | The Tick-Derived Anticoagulant Madanin is Processed by Thrombin and Factor Xa. Plos One, 8, 2013
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